Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

[57] Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria

1975 • 839 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1984 • 567 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

1981 • 449 citations

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

1984 • 443 citations

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

1983 • 423 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Structural analysis of the major immediate early gene of human cytomegalovirus

1984 • 342 citations

Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.

1983 • 318 citations

Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes

1982 • 315 citations

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1982 • 311 citations

The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements

1983 • 299 citations

Promoter-regulatory region of the major immediate early gene of human cytomegalovirus.

1984 • 296 citations

Organization and expression of the immediate early genes of human cytomegalovirus

1983 • 288 citations

Plaque Assay of Cytomegalovirus Strains of Human Origin

1970 • 280 citations

Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptides

1978 • 271 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169

1983 • 199 citations

Synthesis of Proteins and Glycoproteins in Cells Infected with Human Cytomegalovirus

1977 • 184 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

Human cytomegalovirus DNA: Restriction enzyme cleavage maps and map locations for immediate-early, early, and late RNAs

1981 • 171 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Structure and function of the adenovirus origin of replication

1984 • 163 citations

Temporal regulation of human cytomegalovirus transcription at immediate early and early times after infection

1981 • 159 citations

Differentiation between alpha promoter and regulator regions of herpes simplex virus 1: the functional domains and sequence of a movable alpha regulator.

1982 • 148 citations

Growth Characteristics of Cytomegalovirus in Human Fibroblasts with Demonstration of Protein Synthesis Early in Viral Replication

1973 • 142 citations

Analysis of DNA sequences which regulate the transcription of a herpes simplex virus immediate early gene

1984 • 113 citations

Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance

1981 • 102 citations

Expression of recombinant genes containing herpes simplex virus delayed-early and immediate-early regulatory regions and trans activation by herpesvirus infection

1984 • 99 citations

Cloning of the human cytomegalovirus genome as endonuclease XbaI fragments

1981 • 99 citations

Short and long range activation by the SV40 enhancer

1984 • 95 citations

DNA sequences required for the in vitro replication of adenovirus DNA.

1984 • 88 citations

[9] Methods for the preparation of enzyme-antibody conjugates for use in enzyme immunoassay

1981 • 83 citations

Transcriptional regulation of a herpes simplex virus immediate early gene is mediated through an enhancer-type sequence.

1984 • 76 citations

Immediate early antigens in human cytomegalovirus infected cells

1977 • 76 citations

Immunoprecipitation of virus-specific immediate-early and early polypeptides from cells lytically infected with human cytomegalovirus strain AD 169

1981 • 72 citations

Regulation of α Genes of Herpes Simplex Virus: The α 27 Gene Promoter-Thymidine Kinase Chimera Is Positively Regulated in Converted L Cells

1982 • 70 citations

Deoxyribonucleic Acid Synthesis in Synchronized Mammalian KB Cells Infected with Herpes Simplex Virus

1971 • 58 citations

Selective assay for herpes simplex viruses expressing thymidine kinase

1979 • 54 citations

Immediate-early proteins of human cytomegalovirus strains AD169, Davis, and towne differ in electrophoretic mobility

1981 • 52 citations

The α promoter regulator-ovalbumin chimeric gene resident in human cells is regulated like the authentic α 4 gene after infection with herpes simplex virus 1 mutants in α 4 gene

1983 • 29 citations

Induction of Pre‐Early Nuclear Antigen(s) in HEL Cells Infected with Human Cytomegalovirus

1979 • 26 citations

Chicken ovalbumin gene fused to a herpes simplex virus alpha promoter and linked to a thymidine kinase gene is regulated like a viral gene.

1982 • 24 citations

Chicken Ovalbumin Gene Fused to a Herpes Simplex Virus α Promoter and Linked to a Thymidine Kinase Gene Is Regulated Like a Viral Gene

1982 • 17 citations