“Tissue” transglutaminase and apoptosis

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues

1991 • 999 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Transglutaminases

1980 • 818 citations

The ɛ-(γ-Glutamyl)Lysine Crosslink and the Catalytic Role of Transglutaminases

1977 • 813 citations

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

1994 • 617 citations

Premature p34 ^cdc2 Activation Required for Apoptosis

1994 • 568 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

G _h : a GTP-Binding Protein with Transglutaminase Activity and Receptor Signaling Function

1994 • 550 citations

Apoptotic cell death and tissue remodelling during mouse mammary gland involution

1992 • 536 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Inhibition of protein kinase C by calphostin C is light-dependent

1991 • 374 citations

Polyamines as physiological substrates for transglutaminases.

1980 • 310 citations

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.

1996 • 298 citations

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

1995 • 294 citations

Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action

1989 • 254 citations

Tissue Transglutaminase and Apoptosis: Sense and Antisense Transfection Studies with Human Neuroblastoma Cells

1994 • 253 citations

Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.

1996 • 247 citations

Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion.

1992 • 234 citations

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway.

1996 • 228 citations

Differential expression of tissue transglutaminase in human cells

1989 • 226 citations

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

1996 • 207 citations

The clearance of apoptotic cells in the liver is mediated by the asialoglycoprotein receptor

1992 • 185 citations

The expression of "tissue" transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis).

1991 • 183 citations

Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells.

1994 • 183 citations

Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes.

1993 • 179 citations

The ICE family of cysteine proteases as effectors of cell death.

1996 • 158 citations

?Tissue? transglutaminase is specifically expressed in neonatal rat liver cells undergoing apoptosis upon epidermal growth factor-stimulation

1991 • 138 citations

Tissue Transglutaminase-Dependent Posttranslational Modification of the Retinoblastoma Gene Product in Promonocytic Cells Undergoing Apoptosis

1997 • 129 citations

Apoptosis II: The Molecular Basis of Apoptosis in Disease

1994 • 126 citations

Core Histones Are Glutaminyl Substrates for Tissue Transglutaminase

1996 • 124 citations

Identification and Characterization of a Versatile Retinoid Response Element (Retinoic Acid Receptor Response Element-Retinoid X Receptor Response Element) in the Mouse Tissue Transglutaminase Gene Promoter

1996 • 124 citations

Identification of Cytoplasmic Actin as an Abundant Glutaminyl Substrate for Tissue Transglutaminase in HL-60 and U937 Cells Undergoing Apoptosis

1997 • 106 citations

Apoptosis: a potential role for cytosolic transglutaminase and its importance in tumour progression

1991 • 96 citations

Free and protein-conjugated polyamines in mouse epidermal cells. Effect of high calcium and retinoic acid.

1988 • 94 citations

Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins.

1995 • 83 citations

Lack of ‘tissue’ transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLlpr/lpr mice

1997 • 81 citations

Hydrolysis of γ:ϵ Isopeptides by Cytosolic Transglutaminases and by Coagulation Factor XIIIa

1997 • 77 citations

Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein.

1994 • 59 citations

Tissue Transglutaminase: A Candidate Effector Element of Physiological Cell Death

1995 • 56 citations

Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells.

1985 • 52 citations

Molecular changes associated with induction of cell death in a human T-cell leukaemia line: Putative nucleases identified as histones

1989 • 46 citations

Post-translational modification of neuronal proteins: evidence for transglutaminase activity in R2, the giant cholinergic neuron of Aplysia.

1982 • 40 citations

Troponin T cross-linking in human apoptotic cardiomyocytes.

1997 • 35 citations

Identification of promoter region of guinea pig liver transglutaminase gene

1993 • 13 citations