Detection of Philadelphia chromosome-positive cells from glass slide smears using the polymerase chain reaction.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^bcr/abl Gene of the Philadelphia Chromosome

1990 • 2,207 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome.

1987 • 380 citations

Fluorodeoxyuridine synchronization of bone marrow cultures

1983 • 207 citations

Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia

1989 • 183 citations

POLYMERASE CHAIN REACTION FOR DETECTION OF RESIDUAL LEUKAEMIA

1989 • 152 citations

Molecular basis of human von Willebrand disease: analysis of platelet von Willebrand factor mRNA.

1989 • 135 citations

Detection of two alternative bcr/abl mRNA junctions and minimal residual disease in Philadelphia chromosome positive chronic myelogenous leukemia by polymerase chain reaction

1989 • 117 citations

Detection of minimal residual disease in chronic myeloid leukemia patients after bone marrow transplantation by polymerase chain reaction.

1990 • 99 citations

Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid leukemia.

1990 • 89 citations

Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activity.

1987 • 84 citations

Detection of the molecular abnormality in chronic myeloid leukemia by use of the polymerase chain reaction

1988 • 84 citations

Detection by enzymatic amplification of bcr-abl mRNA in peripheral blood and bone marrow cells of patients with chronic myelogenous leukemia

1989 • 72 citations

Cytogenetic and molecular analysis in Philadelphia negative CML

1989 • 65 citations

Utility of molecular genetic analysis of bcr rearrangement in the diagnosis of chronic myeloid leukemia

1987 • 33 citations