In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome.

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

Chromosome Studies on Normal and Leukemic Human Leukocytes

1960 • 1,051 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

The Chronic Myelogenous Leukemia-Specific P210 Protein Is the Product of the bcr / abl Hybrid Gene

1986 • 820 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

Evidence for a multistep pathogenesis of chronic myelogenous leukemia

1981 • 331 citations

Antigens displayed on murine B lymphocyte precursors.

1981 • 299 citations

Alternative 5′ exons in c-abl mRNA

1986 • 290 citations

The arrangement and rearrangement of antibody genes

1978 • 277 citations

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule

1987 • 254 citations

Chronic myelogenous leukemia: recent advances

1985 • 247 citations

Murine B cell lymphopoiesis in long term culture

1984 • 222 citations

A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

1987 • 207 citations

The CML-Specific P210bcr/ablProtein, Unlike v-abl, Does Not Transform NIH/3T3 Fibroblasts

1987 • 181 citations

Nonrandom chromosomal abnormalities in hematologic disorders of man.

1975 • 144 citations

Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.

1986 • 138 citations

Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

1984 • 119 citations

Differentiation of cloned populations of immature B cells after transformation with abelson murine leukemia virus

1983 • 108 citations

B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing.

1987 • 105 citations

In Vitro Analysis of Murine B-Cell Development

1985 • 80 citations

Synergism of v-myc and v-Ha-ras in the in Vitro Neoplastic Progression of Murine Lymphoid Cells

1986 • 78 citations

Abelson virus-infected cells can exhibit restricted in vitro growth and low oncogenic potential

1981 • 76 citations

Progression of the transformed phenotype in clonal lines of Abelson virus-infected lymphocytes.

1983 • 71 citations

BALB- and Harvey-murine sarcoma virus transformation of a novel lymphoid progenitor cell.

1982 • 68 citations

Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus.

1984 • 43 citations

Biosynthesis of murine terminal deoxynucleotidyltransferase.

1980 • 42 citations

Lymphoid bone marrow cultures can reconstitute heterogeneous B and T cell-dependent responses in severe combined immunodeficient mice.

1986 • 41 citations

The Complexity of Virus-Cell Interactions in Abelson Virus Infection of Lymphoid and Other Hematopoietic Cells

1985 • 39 citations

Long-term cultured B lymphocytes and their precursors reconstitute the B-lymphocyte lineage in vivo.

1984 • 32 citations

Leukemogenicity of Clonal Isolates of Murine Leukemia Viruses 2

1978 • 32 citations

Progression of the Transformed Phenotype in Clonal Lines of Abelson Virus-Infected Lymphocytes

1983 • 31 citations