Detection of the molecular abnormality in chronic myeloid leukemia by use of the polymerase chain reaction

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification

1987 • 426 citations

The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia.

1987 • 179 citations

Genomic diversity correlates with clinical variation in Ph′-negative chronic myeloid leukaemia

1986 • 145 citations

Establishment of a Ph ¹ chromosome‐positive cell line from chronic myelogenous leukemia in blast crisis

1983 • 104 citations

CML patients in blast crisis have breakpoints localized to a specific region of the BCR

1987 • 100 citations

The correlation of breakpoint cluster region rearrangement and p210 phl/abl expression with morphological analysis of Ph-negative chronic myeloid leukemia and other myeloproliferative diseases

1988 • 91 citations

Identification of molecular variants of p210bcr-abl in chronic myelogenous leukemia

1987 • 59 citations