1,25-Dihydroxyvitamin D-Responsive Element and Glucocorticoid Repression in the Osteocalcin Gene

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells

1988 • 1,246 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells

1988 • 836 citations

Characterization of a gamma-carboxyglutamic acid-containing protein from bone.

1976 • 782 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease.

1980 • 658 citations

Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties.

1987 • 578 citations

1,25-DIHYDROXYVITAMIN D₃AND MALIGNANT MELANOMA: THE PRESENCE OF RECEPTORS AND INHIBITION OF CELL GROWTH IN CULTURE

1981 • 560 citations

1,25-Dihydroxyvitamin D ₃ : a Novel Immunoregulatory Hormone

1984 • 536 citations

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

1989 • 507 citations

1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells.

1980 • 503 citations

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

1983 • 500 citations

1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells.

1984 • 493 citations

Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

1983 • 424 citations

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1989 • 409 citations

A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells

1986 • 408 citations

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

1986 • 398 citations

Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression.

1989 • 372 citations

Oestrogen and glucocorticoid responsive elements are closely related but distinct

1987 • 353 citations

Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus

1988 • 347 citations

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

1987 • 347 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

Inhibition of human cancer cell growth by 1,25-dihydroxyvitamin D3 metabolites.

1983 • 264 citations

1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells.

1983 • 257 citations

Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3

1988 • 189 citations

Low Serum Osteocalcin Levels in Glucocorticoid-Treated Asthmatics*

1986 • 188 citations

1,25-Dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein

1981 • 158 citations

1,25-DIHYDROXYVITAMIN-D RECEPTOR IN BREAST CANCER CELLS

1979 • 158 citations

Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

1989 • 147 citations

The effects of 1,25-dihydroxyvitamin D3 on human T lymphocyte activation and proliferation: a cell cycle analysis.

1985 • 137 citations

Thyroid Hormone Stimulates Alkaline Phosphatase Activity in Cultured Rat Osteoblastic Cells (ROS 17/2.8) through 3,5,3′-Triiodo-L-Thyronine Nuclear Receptors*

1987 • 121 citations

Age and Menopause-Related Changes in Indices of Bone Turnover*

1989 • 119 citations

Calcitonin and 1,25-dihydroxyvitamin D3 receptors in human breast cancer cell lines.

1980 • 115 citations

1,25-dihydroxyvitamin D3 specifically binds to a human breast cancer cell line (T47D) and stimulates growth

1981 • 99 citations

Regions of the rat osteocalcin gene which mediate the effect of 1,25-dihydroxyvitamin D3 on gene transcription

1989 • 90 citations

Intestinal 1,25-dihydroxyvitamin D3 binding protein: Specificity of binding

1977 • 87 citations

Effects of 1,25‐dihydroxyvitamin D₃ on cell‐cycle kinetics of T 47D human breast cancer cells

1989 • 59 citations

Cell cycle sensitivity of HL-60 cells to the differentiation-inducing effects of 1-alpha,25-dihydroxyvitamin D3.

1985 • 58 citations

Glucocorticoid receptor in clonal osteosarcoma cell lines: A novel system for investigating bone active hormones

1980 • 38 citations