Estrogen-Related Abnormalities in Glomerulosclerosis-Prone Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

2000 • 3,871 citations

Mechanisms of Estrogen Action

2001 • 1,945 citations

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.

1986 • 1,282 citations

Activation mechanisms of matrix metalloproteinases.

1997 • 1,134 citations

Quantitative Zymography: Detection of Picogram Quantities of Gelatinases

1994 • 866 citations

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways

1999 • 785 citations

Intracellular Receptor Concentration Limits Glucocorticoid-Dependent Enhancer Activity*

1987 • 363 citations

Novel Ligands that Function as Selective Estrogens or Antiestrogens for Estrogen Receptor-α or Estrogen Receptor-β*

1999 • 312 citations

Zymography: A Single-Step Staining Method for Quantitation of Proteolytic Activity on Substrate Gels

1997 • 301 citations

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology

2000 • 292 citations

Genetic Variation in Susceptibility to Endocrine Disruption by Estrogen in Mice

1999 • 263 citations

Matrix Metalloproteinases in Renal Development and Disease

2000 • 249 citations

Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat

1996 • 247 citations

Detection of Estrogen Receptor α and β Messenger Ribonucleic Acids in Adult Gonadotropin-Releasing Hormone Neurons1

1999 • 222 citations

Estrogen Directly Represses Gonadotropin-Releasing Hormone (GnRH) Gene Expression in Estrogen Receptor-α (ERα)- and ERβ-Expressing GT1–7 GnRH Neurons1

1999 • 167 citations

Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility

1997 • 166 citations

The limits of the cellular capacity to mediate an estrogen response.

1992 • 131 citations

Expression and Regulation of Estrogen Receptors in Mesangial Cells

2001 • 127 citations

Studies on Binding and Mitogenic Effect of Insulin and Insulin-Like Growth Factor I in Glomerular Mesangial Cells*

1988 • 125 citations

The oestrogen receptor regulates NFκB and AP-1 activity in a cell-specific manner

1998 • 122 citations

Strain differences rather than hyperglycemia determine the severity of glomerulosclerosis in mice

1998 • 90 citations

Dissociation of glomerular hypertrophy, cell proliferation, and glomerulosclerosis in mouse strains heterozygous for a mutation (Os) which induces a 50% reduction in nephron number.

1996 • 86 citations

Estradiol suppresses mesangial cell type I collagen synthesis via activation of the MAP kinase cascade

1999 • 79 citations

Estradiol suppresses type I collagen synthesis in mesangial cells via activation of activator protein-1

1999 • 74 citations

Protein kinase CK2 mediates TGF-β;1-stimulated type IV collagen gene transcription and its reversal by estradiol1

2001 • 72 citations

Mesangial cells from transgenic mice with progressive glomerulosclerosis exhibit stable, phenotypic changes including undetectable MMP-9 and increased type IV collagen.

1996 • 61 citations

Serum-stimulated α₁type IV collagen gene transcription is mediated by TGF-β and inhibited by estradiol

1998 • 60 citations

Murine Matrix Metalloproteinase 9 Gene

1999 • 53 citations

Transcriptional Inhibition of Matrix Metal loproteinase 9 (MMP-9) Activity by a c-fos/Estrogen Receptor Fusion Protein is Mediated by the Proximal AP-1 Site of the MMP-9 Promoter and Correlates with Reduced Tumor Cell Invasion

1999 • 52 citations

Jun N-Terminal Kinase 1 Mediates Transcriptional Induction of Matrix Metal loproteinase 9 Expression

2001 • 52 citations

Genetic susceptibility to nephropathy in insulin‐dependent diabetes: From epidemiology to molecular genetics

1995 • 50 citations

Interacting Quantitative Trait Loci Control Phenotypic Variation in Murine Estradiol-Regulated Responses*

1999 • 49 citations

Age-related changes in alpha 1- and alpha 2-chain type IV collagen mRNAs in adult mouse glomeruli: competitive PCR

1992 • 47 citations

The kidney disease of diabetes mellitus (KDDM): A cell and molecular biology approach

1993 • 44 citations

Glomerular endothelial cells synthesize collagens but little gelatinase A and B.

1998 • 36 citations

The inheritance of glomerulosclerosis in mice is controlled by multiple quantitative trait loci

1998 • 32 citations

Analysis of ligand dependence and hormone response element synergy in transcription by estrogen receptor

1997 • 29 citations

MATRIX ACCUMULATION IN MESANGIAL CELLS EXPOSED TO CYCLOSPORINE A REQUIRES A PERMISSIVE GENETIC BACKGROUND

2000 • 28 citations

Suppression of estrogen-dependent MMP-9 expression by Edpm5, a genetic locus for pituitary tumor growth in rat

2001 • 9 citations