Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Genomic sequencing.

1984 • 8,343 citations

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

1961 • 3,860 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Suppression of arthritis by an inhibitor of nitric oxide synthase.

1993 • 662 citations

The Biosynthesis of Collagen and Its Disorders

1979 • 573 citations

Heritable Diseases of Collagen

1984 • 572 citations

Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide.

1991 • 448 citations

[10] Posttranslational enzymes in the biosynthesis of collagen: Intracellular enzymes

1982 • 406 citations

Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes.

1988 • 391 citations

Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides.

1995 • 389 citations

Nitric-Oxide Mediates Suppression of Cartilage Proteoglycan Synthesis by Interleukin-1

1994 • 374 citations

Behavior of Articular Chondrocytes in Cell Culture

1971 • 319 citations

Modulation of adjuvant arthritis by endogenous nitric oxide

1993 • 316 citations

Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte.

1993 • 302 citations

Nitric oxide and arthritis

1993 • 299 citations

Induction of Nitric Oxide Synthase in Human Chondrocytes

1993 • 286 citations

Nitric Oxide–Generating Compounds Inhibit Total Protein and Collagen Synthesis in Cultured Vascular Smooth Muscle Cells

1995 • 273 citations

The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up-regulated neuronal nitric oxide synthase.

1995 • 256 citations

Modulation by interleukin 1 and tumor necrosis factor α of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes

1990 • 247 citations

Nitric oxide and nitric oxide‐generating compounds inhibit hepatocyte protein synthesis

1991 • 227 citations

Biochemistry of articular cartilage in health and disease

1992 • 217 citations

N‐Monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats

1994 • 213 citations

Post‐Translational Processing of Procollagens

1985 • 200 citations

Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture

1994 • 156 citations

Nitric Oxide Modulates the Synthesis of Extracellular Matrix Proteins in Cultured Rat Mesangial Cells

1995 • 142 citations

Nitric oxide: A signal for ADP-ribosylation of proteins

1994 • 132 citations

The superficial layer of human articular cartilage is more susceptible to interleukin‐1–induced damage than the deeper layers

1996 • 127 citations

Vascular Gene Transfer of the Human Inducible Nitric Oxide Synthase: Characterization of Activity and Effects on Myointimal Hyperplasia

1996 • 103 citations

Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis.

1992 • 94 citations

Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression

1994 • 89 citations

The inducible production of nitric oxide by articular cell types

1994 • 77 citations

[8] Nitric oxide and cartilage metabolism

1996 • 64 citations

Oxygen and Lung Fibrosis

1975 • 51 citations

Inhibition of prolyl hydroxylase by poly(ADP-ribose) and phosphoribosyl-AMP

1989 • 51 citations

Interleukin-1 -induced suppression of type II collagen gene transcription involves DNA regulatory elements

1990 • 32 citations

Poly(ADP-ribose) synthetase activity during bleomycin-induced lung fibrosis in hamsters

1985 • 24 citations

Control of collagen synthesis in human chondrocyte cultures by immune interferon and interleukin-1.

1987 • 21 citations