The Biosynthesis of Collagen and Its Disorders

Aviat space environ med

1992 • 7,493 citations

The Pathogenesis of Atherosclerosis

1976 • 2,000 citations

Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLAST

1974 • 545 citations

Platelet Physiology and Abnormalities of Platelet Function

1975 • 444 citations

Patients with Ehlers-Danlos syndrome type IV lack type III collagen.

1975 • 421 citations

A Heritable Disorder of Connective Tissue

1972 • 412 citations

Changes in type of collagen synthesized as clones of chick chondrocytes grow and eventually lose division capacity.

1976 • 355 citations

Vitamin A-containing lipocytes and formation of type III collagen in liver injury.

1976 • 346 citations

Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts.

1977 • 309 citations

Characterization of the collagen of human hypertrophic and normal scars

1975 • 296 citations

Collagen polymorphism in idiopathic chronic pulmonary fibrosis.

1976 • 264 citations

Urinary Excretion of Hydroxyproline in Health and Disease

1970 • 246 citations

Procollagen Peptidase: An Enzyme Excising the Coordination Peptides of Procollagen

1971 • 232 citations

Simultaneous synthesis of types I and III collagen by fibroblasts in culture.

1976 • 219 citations

Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta.

1975 • 189 citations

Effects of colchicine on collagenase in cultures of rheumatoid synovium

1971 • 189 citations

Differences in Collagen Metabolism between Normal and Osteoarthritic Human Articular Cartilage

1973 • 168 citations

A Collagen Defect in Homocystinuria

1973 • 163 citations

Lysyl-Protocollagen Hydroxylase Deficiency in Fibroblasts from Siblings with Hydroxylysine-Deficient Collagen

1972 • 157 citations

Synthesis of types I and III procollagen and collagen by monkey aortic smooth muscle cells in vitro

1977 • 152 citations

Altered Relation of Two Collagen Types in Osteogenesis Imperfecta

1977 • 143 citations

A hereditary dysplasia of collagen tissues in sheep

1974 • 143 citations

Urinary excretion of hydroxylysine and its glycosides as an index of collagen degradation.

1977 • 133 citations

BIOSYNTHESIS AND MATURATION OF SKIN COLLAGEN IN SCLERODERMA, AND EFFECT OF D-PENICILLAMINE

1974 • 130 citations

Evidence that fibronectin is the collagen receptor on platelet membranes.

1978 • 129 citations

Increase in type I and type III collagens in human alcoholic liver cirrhosis.

1976 • 125 citations

Lysyl Oxidase Deficiency in Ehlers–Danlos Syndrome Type V

1975 • 122 citations

Collagen heterogeneity within different growth regions of long bones of rachitic and nonrachitic chicks

1972 • 118 citations

Decreased lysyl oxidase activity in the aneurysm-prone, mottled mouse.

1977 • 98 citations

Biochemistry of the Renal Glomerular Basement Membrane and Its Alterations in Diabetes Mellitus

1973 • 98 citations

Effect of colchicine on collagen, albumin and transferrin synthesis by cirrhotic rat liver slices

1975 • 95 citations

Age-related variations in hydroxylation of lysine and proline in collagen

1974 • 92 citations

Reducible Crosslinks in Hydroxylysine-Deficient Collagens of a Heritable Disorder of Connective Tissue

1972 • 88 citations

Hydroxylysine-Deficient Skin Collagen in a Patient with a Form of the Ehlers-Danlos Syndrome

1974 • 86 citations

Protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of α-ketoglutarate

1972 • 83 citations

Intracellular enzymes of collagen biosynthesis in rat liver as a function of age and in hepatic injury induced by dimethylnitrosamine. Changes in prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase activities

1976 • 79 citations

Connective tissue synthesis by cultured scleroderma fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts

1976 • 75 citations

Pharmacology of fibrosis: Definitions, limits and perspectives

1975 • 72 citations

Synthesis of collagens Types I and III by pig medial smooth muscle cells in culture

1976 • 71 citations

Characterization of Collagen and Its Precursors Synthesized by Rabbit‐Articular‐Cartilage Cells in Various Culture Systems

1976 • 70 citations

Collagen of Marfan Syndrome is Abnormally Soluble

1973 • 68 citations

Ocular Ehlers-Danlos Syndrome With Normal Lysyl Hydroxylase Activity

1976 • 66 citations

Collagen biosynthesis enzymes in serum and hepatic tissue in liver disease

1979 • 66 citations

Bone collagen metabolism in vitamin D deficiency (Short Communication)

1973 • 64 citations

Radioimmunoassay of Procollagen in Serum of Patients with Paget's Disease of Bone

1976 • 64 citations

Failure of cultured chick embryo fibroblasts to incorporate collagen into their extracellular matrix when transformed by Rous sarcoma virus. An effect of transformation but not of virus production.

1977 • 62 citations

The synthesis of underhydroxylated collagen by 3T6 mouse fibroblasts in culture

1972 • 60 citations

Assay of protocollagen lysyl hydroxylase activity in the skin of human subjects and changes in the activity with age

1973 • 60 citations

Prolyl hydroxylase and an immunologically related protein in mammalian tissues

1974 • 60 citations

Increased collagen synthesis in Kirsten sarcoma virus-transformed BALB 3T3 cells grown in the presence of dibutyryl cyclic AMP

1974 • 58 citations

Abnormal properties of collagen lysyl hydroxylase from skin fibroblasts of siblings with hydroxylysine-deficient collagen.

1976 • 57 citations

Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies

1974 • 56 citations

Effect of cortisol acetate on collagen biosynthesis and on the activities of prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in chick-embryo tendon cells

1977 • 55 citations

Hepatic collagen proline hydroxylase activity in alcoholic liver disease

1976 • 54 citations

Presence of type III collagen in bone from a patient with osteogenesis imperfecta

1977 • 52 citations

Synthesis of collagen by chondrocytes in suspension culture: Modulation by calcium, 3′:5′-cyclic AMP, and prostaglandins

1977 • 51 citations

Immunoreactive prolyl hydroxylase in human skin, serum and synovial fluid: changes in the content and components with age

1977 • 49 citations

Biosynthesis of type I and III collagens by cultured smooth muscle cells from human aorta.

1977 • 49 citations

Prolyl Hydroxylase Activity in Normal and Diseased Human Liver

1976 • 47 citations

Age-related changes in human skin collagen galactosyltransferase and collagen glucosyltransferase activities

1977 • 44 citations

Collagen glucosyltransferase activity in human serum

1977 • 42 citations

Effects of lysosomal enzymes on the type of collagen synthesized by bovine articular cartilage

1973 • 40 citations

Experimental Esophageal Lye Burns

1973 • 40 citations

Effect of prednisolone on the activities of the intracellular enzymes of collagen biosynthesis in rat liver and skin

1977 • 39 citations

Serum immunoreactive prolyl hydroxylase in liver disease

1977 • 37 citations

Native collagen is not a substrate for the collagen glucosyltransferase of platelets

1976 • 34 citations

Comparison of the cyanogen bromide peptides of insoluble guinea-pig skin and scar collagen

1975 • 34 citations

Hydroxyproline contents and prolyl hydroxylase activities in lungs of rats exposed to low levels of ozone

1976 • 30 citations

Increased collagen synthesis and the kinetic characteristics of prolyl hydroxylase in tissues of rabbits with experimental arteriosclerosis

1976 • 29 citations

Age-related variations in glycosylation of hydroxylysine in human and rat skin collagens

1975 • 29 citations

Prolyl hydroxylase activity in L-929 fibroblasts incubated with and without ascorbate

1976 • 28 citations

Tetramers and Monomers of Prolyl Hydroxylase in Isolated Chick-Embryo Tendon Cells. The Association of Inactive Monomers to Active Tetramers and a Preliminary Characterization of the Intracellular Monomer-Size Protein

1977 • 27 citations

Radioimmunoassay for aminoterminal procollagen peptides in liver disease

1978 • 25 citations

Intracellular enzymes of collagen biosynthesis in rat kidney in streptozotocin diabetes

1976 • 25 citations

Intracellular enzymes of collagen biosynthesis in human platelets

1977 • 22 citations

Comparative studies on collagen glycosylation in chick skin and bone

1977 • 20 citations

Effect of cis-hydroxyproline on collagen and other proteins in skin wounds, granuloma tissue, and liver of mice and rats

1974 • 19 citations

Reduction of collagen biosynthesis in blood vessels and other tissues by reserpine and hypophysectomy

1977 • 18 citations

Collagen and Elastin in Scleroderma

1974 • 10 citations

Colchicine: Effects upon urinary hydroxyproline excretion in patients with scleroderma

1975 • 7 citations