Structure and function of epidermal growth factor‐like regions in proteins

Epidermal Growth Factor

1979 • 2,964 citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 • 1,241 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Complete nucleotide sequences of the gene for human factor IX (antihemophilic factor B)

1985 • 683 citations

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding

1987 • 677 citations

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

1987 • 625 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

Characterization of a cDNA coding for human factor VII.

1986 • 450 citations

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.

1987 • 381 citations

lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor

1985 • 369 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

The nucleotide sequence of the gene for human protein C.

1985 • 360 citations

Deletion in Cysteine-Rich Region of LDL Receptor Impedes Transport to Cell Surface in WHHL Rabbit

1986 • 335 citations

The solution structure of human epidermal growth factor

1987 • 322 citations

Human epidermal growth factor precursor: cDNA sequence, expressionin vitroand gene organization

1986 • 321 citations

The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain

1982 • 312 citations

Epidermal Growth Factor

1973 • 233 citations

Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor).

1985 • 232 citations

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C

1986 • 204 citations

Biologically active synthetic fragments of epidermal growth factor: localization of a major receptor-binding region.

1984 • 133 citations

Complete Nucleotide Sequences of Two Adjacent Early Vaccinia Virus Genes Located Within the Inverted Terminal Repetition

1982 • 133 citations

Primary structure of bovine vitamin K-dependent protein S.

1986 • 126 citations

Laminin — a multifunctional protein of basement membranes

1983 • 125 citations

A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule.

1986 • 91 citations

Amino acid sequence of bovine protein Z: a vitamin K‐dependent serine protease homolog

1985 • 83 citations

The purification of fully active recombinant transforming growth factor alpha produced in Escherichia coli.

1986 • 68 citations

The LDL Receptor in Familial Hypercholesterolemia: Use of Human Mutations to Dissect a Membrane Protein

1986 • 56 citations

Identification of a factor IX/IXa binding protein on the endothelial cell surface.

1987 • 28 citations