Molecular requirements for the mu-induced light chain gene rearrangement in pre-B cells.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Immunoglobulin heavy chain binding protein

1983 • 849 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

CELLULAR LOCALIZATION OF IMMUNOGLOBULINS WITH DIFFERENT ALLOTYPIC SPECIFICITIES IN RABBIT LYMPHOID TISSUES

1965 • 444 citations

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1989 • 432 citations

Molecular components of the B-cell antigen receptor complex of the IgM class

1990 • 401 citations

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1987 • 346 citations

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.

1987 • 343 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes.

1987 • 306 citations

λ5, a new light-chain-related locus selectively expressed in pre-B lymphocytes

1986 • 302 citations

Allelic Exclusion in Transgenic Mice That Express the Membrane form of Immunoglobulin μ

1987 • 293 citations

B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties.

1988 • 283 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine

1990 • 245 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.

1981 • 236 citations

The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface.

1990 • 221 citations

A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells.

1988 • 209 citations

B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex.

1990 • 208 citations

Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.

1987 • 187 citations

Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice

1984 • 184 citations

Formation of disulphide-linked µ2ω2 tetramers in pre-B cells by the 18K ω-immunoglobulin light chain

1987 • 179 citations

A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes

1985 • 169 citations

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.

1988 • 138 citations

Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins.

1989 • 128 citations

Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM.

1990 • 126 citations

Effective radioiodination by lactoperoxidase and solubilisation of cell-surface proteins of cultured murine T lymphoma cells

1975 • 106 citations

Mu heavy chains can associate with a pseudo-light chain complex (ψL) in human pre-B cell lines

1989 • 105 citations

Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain

1984 • 105 citations

The sequence of the mu transmembrane segment determines the tissue specificity of the transport of immunoglobulin M to the cell surface.

1990 • 101 citations

Deletions in immunoglobulin mu chains.

1982 • 98 citations

Light-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virus.

1989 • 97 citations

Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis.

1985 • 79 citations

Two types of mu chain complexes are expressed during differentiation from pre-B to mature B cells.

1990 • 76 citations

Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice

1987 • 70 citations

The Omega and Iota Surrogate Immunoglobulin Light Chains

1988 • 56 citations

Cellular Stages and Molecular Steps of Murine B-cell Development

1989 • 44 citations

Allelic exclusion in transgenic mice carrying mutant human IgM genes.

1988 • 42 citations

Cloning and sequencing of mouse ribosomal protein S12 cDNA

1989 • 36 citations

A novel germ-line J_Ktranscript starting immediately upstream of J_K1

1989 • 34 citations

Association of Ig L chain-like protein lambda 5 with a 16-kilodalton protein in mouse pre-B cell lines is not dependent on the presence of Ig H chain protein.

1990 • 29 citations

The Effect of the scid Mutation on Mechanism and Control of Immunoglobulin Heavy and Light Chain Gene Rearrangement

1989 • 7 citations