Deletions in immunoglobulin mu chains.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

Speculations on RNA splicing

1981 • 639 citations

A complete immunoglobulin gene is created by somatic recombination.

1978 • 610 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

1978 • 495 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes

1981 • 260 citations

5′ Flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains

1980 • 238 citations

The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.

1981 • 236 citations

Evidence that murine pre-B cells synthesise μ heavy chains but no light chains

1979 • 208 citations

Somatic mutation of immunoglobulin light-chain variable-region genes

1981 • 184 citations

Effect of Tunicamycin on IgM, IgA, and IgG Secretion by Mouse Plasmacytoma Cells

1978 • 180 citations

Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences

1981 • 173 citations

A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events

1980 • 158 citations

Heavy Chain Diseases: Current Findings and Concepts

1979 • 150 citations

The immunoglobulin μ chains of membrane-bound and secreted IgM molecules differ in their C-terminal segments

1980 • 148 citations

Amino acid sequence of a mouse immunoglobulin mu chain.

1979 • 134 citations

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse.

1978 • 134 citations

The complete amino acid sequence of a mouse ϰ light chain

1972 • 124 citations

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing

1980 • 121 citations

Immunoglobulin production by lymphocyte hybridomas

1978 • 111 citations

Complete nucleotide sequence of mouse imunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes

1980 • 108 citations

Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class.

1980 • 101 citations

B lymphocyte differentiation and the control of IgM μ chain expression

1981 • 98 citations

RNA splicing generates a variant light chain from an aberrantly rearranged κ gene

1980 • 95 citations

Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing

1981 • 90 citations

Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line.

1981 • 78 citations

Structural Variants of Human and Murine Immunoglobulins

1975 • 71 citations

Murine heavy chain disease

1978 • 63 citations

Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.

1980 • 59 citations

Roles of protein and carbohydrate in glycoprotein processing and secretion. Studies using mutants expressing altered IgM mu chains.

1981 • 42 citations

An unusual translocation of immunoglobulin gene segments in variants of the mouse myeloma MPC11

1980 • 40 citations

Sequentially Derived Mutants of the Constant Region of the Heavy Chain of Murine Immunoglobulins

1979 • 39 citations

DNA sequence of the constant gene region of the mouse immunoglobulin kappa chain

1981 • 36 citations