Insulin-Like Growth Factors

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

Role of insulin-like growth factors in embryonic and postnatal growth

1993 • 2,349 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor

1995 • 1,361 citations

Insulin Resistance — Mechanisms, Syndromes, and Implications

1991 • 788 citations

Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta.

1985 • 436 citations

Dietary components that regulate serum somatomedin-C concentrations in humans.

1983 • 433 citations

The Molecular Mechanism of Insulin Action

1985 • 424 citations

Synthesis and Secretion of Insulin-like Growth Factor II by a Leiomyosarcoma with Associated Hypoglycemia

1988 • 346 citations

Insulin-like Growth Factors and Cancer

1995 • 321 citations

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors.

1990 • 242 citations

Effects of insulin-like growth factor on linear growth, head circumference, and body fat in patients with Laron-type dwarfism

1992 • 206 citations

Insulin-like Growth Factors in Health and Disease

1992 • 164 citations

Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus.

1992 • 146 citations

Clinical Uses of Insulin-like Growth Factor I

1994 • 138 citations

Recombinant human insulin-like growth factor I (rhIGF I) reduces hyperglycaemia in patients with extreme insulin resistance

1991 • 115 citations

Insulinlike growth factors and their receptors as growth regulators in normal physiology and pathologic states

1991 • 109 citations

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

1992 • 107 citations

Impaired Formation of the Ternary Insulin-Like Growth Factor-Binding Protein Complex in Patients with Hypoglycemia due to Nonislet Cell Tumors*

1991 • 105 citations

Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes

1996 • 69 citations

Glucose utilization in a patient with hepatoma and hypoglycemia. Assessment by a positron emission tomography.

1992 • 69 citations

Insulin-Like Growth Factor-1 Therapy in Diabetes: Physiologic Basis, Clinical Benefits, and Risks

1994 • 62 citations

Insulin-Like Growth Factor-II in Nonislet Cell Tumors Associated with Hypoglycemia: Increased Levels of Messenger Ribonucleic Acid*

1989 • 55 citations

Trial of insulinlike growth factor I therapy for patients with extreme insulin resistance syndromes

1993 • 52 citations

Serum levels of insulin‐like growth factor (IGF) I, II and IGF binding protein in diabetic adolescents treated with continuous subcutaneous insulin infusion

1989 • 51 citations

Prolonged treatment with recombinant insulin-like growth factor-I in children with growth hormone insensitivity syndrome--a clinical research center study. GHIS Collaborative Group

1996 • 49 citations

IGFs: function and clinical importance 3 Role of insulin‐like growth factor (IGF) II and IGF binding proteins in extrapancreatic tumour hypoglycaemia

1993 • 48 citations

Treatment with recombinant human insulin-like growth factor I of children with growth hormone receptor deficiency (Laron syndrome). Kabi Pharmacia Study Group on Insulin-like Growth Factor I Treatment in Growth Hormone Insensitivity Syndromes.

1992 • 45 citations

Insulin-like growth factor I (rhIGF-I) as a therapeutic agent for hyperinsulinemic insulin-resistant diabetes mellitus

1995 • 40 citations

Adverse effects of recombinant human insulin-like growth factor I in obese insulin-resistant type II diabetic patients

1994 • 32 citations

Insulin-like growth factors (IGFs) and IGF-I treatment in the adolescent with insulin-dependent diabetes mellitus

1995 • 30 citations

Clinical review 59: Uses of human insulin-like growth factor-I in clinical conditions

1994 • 22 citations

The effects of subcutaneous insulin-like growth factor-I infusion in insulin-dependent diabetes mellitus

1994 • 21 citations

Disorders of growth hormone resistance in childhood

1993 • 15 citations

Growth hormone therapy for adult growth hormone deficiency

1996 • 14 citations

High dose intravenous, but not low dose subcutaneous, insulin-like growth factor-I therapy induces sustained insulin sensitivity in severely resistant type I diabetes mellitus

1994 • 8 citations

[Insulin-like growth factors and their receptors].

1990 • 4 citations