Insulin-like growth factors (IGFs) and IGF-I treatment in the adolescent with insulin-dependent diabetes mellitus

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

Impaired Insulin Action in Puberty

1986 • 938 citations

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

1981 • 829 citations

Insulin‐Like Growth Factors I and II: Some Biological Actions and Receptor Binding Characteristics of Two Purified Constituents of Nonsuppressible Insulin‐Like Activity of Human Serum

1978 • 384 citations

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes.

1994 • 328 citations

Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects.

1989 • 320 citations

Insulin-like Growth Factors

1983 • 278 citations

INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-1 MODULATES BLOOD GLUCOSE LEVELS

1991 • 262 citations

Insulin-Like Growth Factors in Vitreous: Studies in Control and Diabetic Subjects with Neovascularization

1986 • 255 citations

Somatogenic Receptors of Rat Liver: Regulation by Insulin*

1980 • 230 citations

Pathogenesis of the Dawn Phenomenon in Patients with Insulin-Dependent Diabetes Mellitus

1985 • 213 citations

Effect of Diabetes and its Control on Insulin-like Growth Factors in the Young Subject with Type I Diabetes

1984 • 189 citations

ORCADIAN VARIATION OF GH‐INDEPENDENT IGF‐BINDING PROTEIN IN DIABETES MELLITUS AND ITS RELATIONSHIP TO INSULIN. A NEW ROLE FOR INSULIN?

1988 • 185 citations

IGF binding proteins: regulation of cellular actions.

1992 • 176 citations

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin- dependent diabetes

1994 • 143 citations

The Growth Hormone (GH)-Releasing Hormone (GHRH)- GH-Somatomedin Axis: Evidence for Rapid Inhibition of GHRH-Elicited GH Release by Insulin-Like Growth Factors I and II*

1987 • 138 citations

Insulinlike growth factor I regulation of growth hormone gene transcription in primary rat pituitary cells.

1987 • 138 citations

THE GROWTH HORMONE INDEPENDENT INSULIN‐LIKE GROWTH FACTOR‐I BINDING PROTEIN BP‐28 IS ASSOCIATED WITH SERUM INSULIN‐LIKE GROWTH FACTOR‐I INHIBITORY BIOACTIVITY IN ADOLESCENT INSULIN‐DEPENDENT DIABETICS

1990 • 133 citations

Increased Overnight Growth Hormone Concentrations in Diabetic Compared with Normal Adolescents

1990 • 128 citations

Growth During Childhood and Final Height in Type 1 Diabetes

1994 • 113 citations

Abnormal Regulation of Insulin-Like Growth Factor Binding Proteins in Adolescents with Insulin-Dependent Diabetes*

1991 • 112 citations

Characterization of the insulin-antagonistic effect of growth hormone in man

1991 • 97 citations

Nocturnal spikes of growth hormone secretion cause the dawn phenomenon in Type 1 (insulin-dependent) diabetes mellitus by decreasing hepatic (and extrahepatic) sensitivity to insulin in the absence of insulin waning

1990 • 89 citations

The role of growth hormone in diabetes mellitus

1988 • 86 citations

Association of Elevated IGF-I Levels With Increased Retinopathy in Late-Onset Diabetes

1991 • 84 citations

Loss of the normal relationships between growth hormone, growth hormone‐binding protein and insulin‐like growth factor‐I in adolescents with insulin‐dependent diabetes mellitus

1994 • 81 citations

Insulin-like growth factors in vitreous. Studies in control and diabetic subjects with neovascularization

1986 • 78 citations

The effects of recombinant insulin-like growth factor I administration on growth hormone levels and insulin requirements in adolescents with Type 1 (insulin-dependent) diabetes mellitus

1993 • 78 citations

Diabetes in puberty.

1992 • 75 citations

The Dawn Phenomenon Is Related To Overnight Growth Hormone Release In Adolescent Diabetics

1990 • 74 citations

Diminished growth hormone-binding protein in children with insulin-dependent diabetes mellitus

1992 • 74 citations

Biochemical and hormonal changes induced by one week of administration of rIGF‐I to patients with Laron type dwarfism

1991 • 72 citations

Report On The Nomenclature Of The IGF Binding Proteins

1990 • 70 citations

The growth hormone insulin-like growth factor axis in kidney revisited

1993 • 60 citations

Diurnal Growth Hormone and Glucose Abnormalities in Unstable Diabetics: Studies of Ambulatory-Fed Subjects during Continuous Blood Glucose Analysis

1972 • 60 citations

Comparison of Peripheral and Portal (Via the Umbilical Vein) Routes of Insulin Infusion in IDDM Patients

1992 • 59 citations

The Role of Growth Hormone in the Development of Diabetic Retinopathy

1994 • 59 citations

Somatomedin-C/IGF-I measured by radioimmunoassay and somatomedin bioactivity in adolescents with insulin dependent diabetes compared with puberty matched controls.

1988 • 56 citations

Effect of diabetes and its control on insulin-like growth factors in the young subject with type I diabetes

1984 • 55 citations

Relationships Between Growth Factors (Somatomedin-C and Growth Hormone) and Body Development, Metabolic Control, and Retinal Changes in Children and Adolescents With IDDM

1986 • 49 citations

Diminished growth hormone-binding protein in children with insulin- dependent diabetes mellitus

1992 • 47 citations

Serum levels of growth hormone-binding protein and insulin-like growth factor I in children and adolescents with Type 1 (insulin-dependent) diabetes mellitus

1993 • 47 citations

Is Insulinlike Growth Factor I Associated With Diabetic Retinopathy?

1990 • 44 citations

Serum IGF‐1 Concentration in Diabetic Retinopathy

1988 • 43 citations

The serum growth hormone-binding protein is reduced in young patients with insulin-dependent diabetes mellitus.

1993 • 40 citations

Pituitary Response to Growth Hormone–Releasing Hormone in IDDM: Abnormal Responses to Insulin and Hyperglycemia

1992 • 36 citations

Association of elevated IGF-I levels with increased retinopathy in late-onset diabetes

1991 • 33 citations

Growth hormone and insulin-like growth factor I in human and experimental diabetes

1993 • 33 citations

Evidence for a Role for Insulin and Growth Hormone in Overnight Regulation of 3-Hydroxybutyrate in Normal and Diabetic Adolescents

1993 • 33 citations

Circulating insulin-like growth factor I in Type 1 (insulin-dependent) diabetic patients with retinopathy

1989 • 33 citations

Growth hormone and insulin-like growth factor I in human and experimental diabetes

1994 • 33 citations

The effects of recombinant human insulin‐like growth factor I on growth hormone secretion in adolescents with insulin dependent diabetes mellitus

1994 • 32 citations

Relationships between growth factors (somatomedin-C and growth hormone) and body development, metabolic control, and retinal changes in children and adolescents with IDDM

1986 • 28 citations

Dawn phenomenon in Type 1 (insulin-dependent) diabetic adolescents: influence of nocturnal growth hormone secretion

1988 • 28 citations

Is insulinlike growth factor I associated with diabetic retinopathy?

1990 • 26 citations

The frequency and amplitude of growth hormone secretory episodes as determined by deconvolution analysis are increased in adolescents with insulin dependent diabetes mellitus and are unaffected by short‐term euglycaemia

1993 • 26 citations

Insulin Therapy Increases Low Plasma Growth Hormone Binding Protein in Children with New‐onset Type 1 Diabetes

1993 • 26 citations

Contrasting metabolic effects of continuous and pulsatile growth hormone administration in young adults with Type 1 (insulin-dependent) diabetes mellitus

1992 • 26 citations

The serum growth hormone-binding protein is reduced in young patients with insulin-dependent diabetes mellitus

1993 • 24 citations

Failure of current insulin regimes to meet the overnight requirements of adolescents with insulin-dependent diabetes.

1990 • 21 citations

Report on the nomenclature of the IGF binding proteins

1992 • 20 citations

Abnormal growth hormone levels in insulin-dependent diabetic patients under continuous subcutaneous insulin infusion and intensified conventional treatment

1984 • 20 citations

Comparison of peripheral and portal (via the umbilical vein) routes of insulin infusion in IDDM patients

1992 • 19 citations

Half‐life of exogenous growth hormone following suppression of endogenous growth hormone secretion with somatostatin in type I (insulin‐dependent) diabetes mellitus

1992 • 19 citations

Diurnal plasma profiles of metabolite and hormone concentration in insulin-dependent diabetic patients during conventional insulin treatment and continuous subcutaneous insulin infusion

1987 • 19 citations

The Dawn Phenomenon: Comparison between Normal and Insulin-Dependent Diabetic Adolescents

1992 • 15 citations