Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

A direct link between core histone acetylation and transcriptionally active chromatin.

1988 • 905 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae

1987 • 676 citations

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

1994 • 539 citations

Nucleosome loss activates yeast downstream promoters in vivo

1988 • 456 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Genomic Sequencing and Methylation Analysis by Ligation Mediated PCR

1989 • 408 citations

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

1987 • 394 citations

The organization and transcription of the galactose gene cluster of Saccharomyces

1981 • 350 citations

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.

1990 • 350 citations

Genetic Analysis of Histone H4: Essential Role of Lysines Subject to Reversible Acetylation

1990 • 346 citations

The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro

1986 • 339 citations

Histone acetylation and control of gene expression

1991 • 331 citations

Yeast histone H4 N-terminal sequence is required for promoter activation in vivo

1991 • 330 citations

Saccharomyces telomeres assume a non-nucleosomal chromatin structure.

1992 • 275 citations

Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo.

1992 • 227 citations

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast

1994 • 227 citations

Chromatin and Chromosome Structure

1977 • 191 citations

Active genes in budding yeast display enhanced in vivo accessibility to foreign DNA methylases: a novel in vivo probe for chromatin structure of yeast.

1992 • 188 citations

Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.

1992 • 186 citations

Notes: Point Mutations in the Yeast Histone H4 Gene Prevent Silencing of the Silent Mating Type Locus HML

1990 • 168 citations

Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4.

1992 • 160 citations

A functional role for nucleosomes in the repression of a yeast promoter.

1991 • 156 citations

Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci.

1992 • 120 citations

GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo.

1993 • 109 citations

Organization of theGAL1–GAL10intergeaic control region chromatin

1984 • 80 citations

Upstream Activation Sequence-Dependent Alteration of Chromatin Structure and Transcription Activation of the Yeast GAL1-GAL10 Genes

1989 • 76 citations

A transcriptionally regulated expression vector for the fission yeast Schizosaccharomyces pombe

1989 • 75 citations

Nucleosome loss activates CUP1 and HIS3 promoters to fully induced levels in the yeast Saccharomyces cerevisiae.

1992 • 75 citations

Positioned nucleosomes inhibit Dam methylation invivo.

1994 • 75 citations

A simpler and better method to cleave chromatin with DNase1 for hypersensitive site analyses

1991 • 46 citations

Expression of the Escherichia coli dam methylase in Saccharomyces cerevisiae: effect of in vivo adenine methylation on genetic recombination and mutation.

1985 • 40 citations

In vivo "photofootprint" changes at sequences between the yeast GAL1 upstream activating sequence and "TATA" element require activated GAL4 protein but not a functional TATA element.

1988 • 25 citations

Nucleosome Loss Activates CUP1 and HIS3 Promoters to Fully Induced Levels in the Yeast Saccharomyces cerevisiae

1992 • 19 citations

Expression of the Escherichia coli dam Methylase in Saccharomyces cerevisiae: Effect of In Vivo Adenine Methylation on Genetic Recombination and Mutation

1985 • 11 citations