In vivo "photofootprint" changes at sequences between the yeast GAL1 upstream activating sequence and "TATA" element require activated GAL4 protein but not a functional TATA element.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

A new class of yeast transcriptional activators

1987 • 706 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Saccharomyces cerevisiae GAL1-GAL10 Divergent Promoter Region: Location and Function of the Upstream Activating Sequence UAS_G

1984 • 395 citations

The organization and transcription of the galactose gene cluster of Saccharomyces

1981 • 350 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae.

1985 • 342 citations

Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 310 citations

Multiple DNA-pRotein Interactions Governing High-Precision DNA Transactions

1986 • 302 citations

Transformation of yeast spheroplasts without cell fusion

1987 • 266 citations

The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiae.

1985 • 265 citations

A fast and simple method for sequencing DNA cloned in the single-stranded bacteriophage M13

1979 • 257 citations

Specific protein binding to far upstream activating sequences in polymerase II promoters.

1985 • 246 citations

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1987 • 226 citations

Use of light for footprinting DNA in vivo

1984 • 181 citations

Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms.

1986 • 181 citations

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.

1987 • 161 citations

Transcription initiation of the Saccharomyces cerevisiae iso-1-cytochrome c gene

1986 • 121 citations

Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxes

1987 • 117 citations

DNA translocation by the restriction enzyme from E. coli K

1980 • 116 citations

In vivo DNA-binding properties of a yeast transcription activator protein.

1987 • 112 citations

The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection.

1987 • 108 citations

Use of lacZ Fusions to Delimit Regulatory Elements of the Inducible Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 90 citations

The DNA restriction endonuclease of Escherichia coli B. I. Studies of the DNA translocation and the ATPase activities.

1985 • 58 citations

Colony probing as an alternative to standard sequencing as a means of direct analysis of chromosomal DNA to determine the spectrum of single-base changes in regions of known sequence.

1986 • 55 citations

Constitutive and Inducible Saccharomyces cerevisiae Promoters: Evidence for Two Distinct Molecular Mechanisms

1986 • 52 citations

In Vivo DNA-Binding Properties of a Yeast Transcription Activator Protein

1987 • 38 citations

Interaction of GAL4 and GAL80 Gene Regulatory Proteins In Vitro

1987 • 31 citations

Oligodeoxynucleotide-Directed Mutagenesis ofEscherichia coliand Yeast by Simple Cotransformation of the Primer and Template

1986 • 29 citations