Prophylactic Cranial Irradiation in Extensive-stage Small Cell Lung Cancer

NCT04947774

NULLOBSERVATIONAL

Chinese Academy of Medical Sciences

100 participants

Started 2020-11-01 · Completed 2022-10

Status: Unknown (as of 12-23-2025)

Conditions

Extensive-stage Small-cell Lung Cancer

Interventions

RADIATION: Prophylactic Cranial Irradiation

Linked Papers (from SciSciNet-V2)

Total Papers16

Background

5

Result

0

Derived

0

Unknown

11

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

The prognosis of extensive-stage small cell lung cancer is still very poor, even for those who received chemotherapy and immunotherapy. This experimental study is a real-world research design to evaluate the effectiveness and safety of prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer who with first-line chemotherapy combined with immunotherapy.

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Background Papers10

Phase III Trial of Irinotecan/Cisplatin Compared With Etoposide/Cisplatin in Extensive-Stage Small-Cell Lung Cancer: Clinical and Pharmacogenomic Results From SWOG S0124

Phase III Trial of Irinotecan/Cisplatin Compared With Etoposide/Cisplatin in Extensive-Stage Small-Cell Lung Cancer: Clinical and Pharmacogenomic Results From SWOG S0124

Cancer incidence and mortality in China in 2013: an analysis based on urbanization level

Cancer incidence and mortality in China in 2013: an analysis based on urbanization level

Rates of Overall Survival and Intracranial Control in the Magnetic Resonance Imaging Era for Patients With Limited-Stage Small Cell Lung Cancer With and Without Prophylactic Cranial Irradiation

Rates of Overall Survival and Intracranial Control in the Magnetic Resonance Imaging Era for Patients With Limited-Stage Small Cell Lung Cancer With and Without Prophylactic Cranial Irradiation

The effects of prophylactic cranial irradiation versus control on survival of patients with extensive-stage small-cell lung cancer: a meta-analysis of 14 trials

The effects of prophylactic cranial irradiation versus control on survival of patients with extensive-stage small-cell lung cancer: a meta-analysis of 14 trials

Prophylactic cranial irradiation for extensive-stage small cell lung cancer: Analysis based on active brain MRI surveillance

Prophylactic cranial irradiation for extensive-stage small cell lung cancer: Analysis based on active brain MRI surveillance

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers11

Global cancer statistics, 2012

26,048 citations

Changing Epidemiology of Small-Cell Lung Cancer in the United States Over the Last 30 Years: Analysis of the Surveillance, Epidemiologic, and End Results Database

1,745 citations

Phase III Study of Concurrent Versus Sequential Thoracic Radiotherapy in Combination With Cisplatin and Etoposide for Limited-Stage Small-Cell Lung Cancer: Results of the Japan Clinical Oncology Group Study 9104

Phase III Study of Pemetrexed Plus Carboplatin Compared With Etoposide Plus Carboplatin in Chemotherapy-Naive Patients With Extensive-Stage Small-Cell Lung Cancer

Twenty‐five years of clinical research for patients with limited‐stage small cell lung carcinoma in North America

Prophylactic Cranial Irradiation for Small-Cell Lung Cancer: Time for a Reassessment

Prophylactic Cranial Irradiation for Resectable Small-Cell Lung Cancer

Is prophylactic cranial irradiation (PCI) needed in patients with extensive-stage small cell lung cancer showing complete response to first-line chemotherapy?

Meta-analysis of prophylactic cranial irradiation or not in treatment of extensive-stage small-cell lung cancer: The dilemma remains

Amrubicin and carboplatin with pegfilgrastim in patients with extensive stage small cell lung cancer: A phase II trial of the Sarah Cannon Oncology Research Consortium