Prediction of Significant Hepatic Fibrosis in HCV Carriers With PNALT by SAPI- A Validation Study

NCT00466271

NULLOBSERVATIONAL

National Taiwan University Hospital

102 participants

Started 2007-04 · Completed 2008-12

Status: Completed (as of 12-23-2025)

Conditions

Chronic Hepatitis CHepatic Fibrosis

Interventions

Linked Papers (from SciSciNet-V2)

Total Papers29

Background

0

Result

0

Derived

0

Unknown

29

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

The purpose of the study is to validate the diagnostic accuracy and reproducibility of SAPI to predict significant hepatic fibrosis in HCV patients with PNALT who are scheduled to receive combination therapy with pegylated interferon plus ribavirin and percutaneous liver biopsies.

Sort by:

Background Papers0

No background papers linked

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers29

A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C

4,023 citations

Hepatitis C Virus Infection

2,979 citations

Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C

2,424 citations

Sampling variability of liver fibrosis in chronic hepatitis C

2,191 citations

Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study

1,432 citations

Complications following percutaneous liver biopsy

1,184 citations

Practices of Liver Biopsy in France: Results of a Prospective Nationwide Survey

Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease

A 21-year experience with major hemorrhage after percutaneous liver biopsy

Routes of Infection, Viremia, and Liver Disease in Blood Donors Found to Have Hepatitis C Virus Infection

SAMPLING VARIABILITY AND ITS INFLUENCE ON THE DIAGNOSTIC YIELD OF PERCUTANEOUS NEEDLE BIOPSY OF THE LIVER

Validity and Clinical Utility of the Aspartate Aminotransferase–Alanine Aminotransferase Ratio in Assessing Disease Severity and Prognosis in Patients With Hepatitis C Virus–Related Chronic Liver Disease

Slow progression rate of fibrosis in hepatitis C virus patients with persistently normal alanine transaminase activity

Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C

Age and platelet count: a simple index for predicting the presence of histological lesions in patients with antibodies to hepatitis C virus

Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels

Natural history of hepatitis C virus carriers with persistently normal aminotransferase levels

Clinical, histological, and virological features of hepatitis C virus carriers with persistently normal or abnormal alanine transaminase levels

Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases

Predictive value of ALT levels for histologic findings in chronic hepatitis C: A European collaborative study

Prevalence of Liver Disease in a Population of Asymptomatic Persons with Hepatitis C Virus Infection

Prospective study on anti-hepatitis C virus–positive patients with persistently normal serum alanine transaminase with or without detectable serum hepatitis C virus RNA

Treatment of patients with hepatitis C and normal serum aminotransferase levels

Clinical features of hepatitis C-infected patients with persistently normal alanine transaminase levels in the southwestern United States

A follow-up study to determine the value of liver biopsy and need for antiviral therapy for hepatitis C virus carriers with persistently normal serum aminotransferase

Clinical management of HCV carriers with normal aminotransferase levels

Assessment of liver fibrosis progression in patients with chronic hepatitis C and normal alanine aminotransferase values: The role of AST to the platelet ratio index

Chronic hepatitis C with normal aminotransferase levels