A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C

Histological grading and staging of chronic hepatitis

1995 • 4,862 citations

Chronic hepatitis B

2007 • 3,079 citations

Hepatitis C Virus Infection

2001 • 2,979 citations

Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection

2002 • 1,981 citations

Intraobserver and Interobserver Variations in Liver Biopsy Interpretation in Patients with Chronic Hepatitis C

1994 • 1,968 citations

Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study

2001 • 1,432 citations

Identification of chronic hepatitis C patients without hepatic fibrosis by a simple predictive model

2002 • 1,078 citations

Practices of Liver Biopsy in France: Results of a Prospective Nationwide Survey

2000 • 986 citations

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

2002 • 894 citations

Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia.

1966 • 823 citations

UK guidelines on the management of variceal haemorrhage in cirrhotic patients

2015 • 709 citations

Chronic hepatitis B

2001 • 694 citations

The long-term pathological evolution of chronic hepatitis C

1996 • 594 citations

AST/ALT Ratio Predicts Cirrhosis in Patients With Chronic Hepatitis C Virus Infection

1998 • 516 citations

Ratio of Serum Aspartate to Alanine Aminotransferase in Chronic Hepatitis Relationship to Cirrhosis

1988 • 497 citations

The role of liver biopsy in chronic hepatitis C

2002 • 354 citations

Prevention of spread of hepatitis C

2002 • 331 citations

Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection

2001 • 277 citations

The role of liver biopsy in chronic hepatitis C

2001 • 273 citations

Age and platelet count: a simple index for predicting the presence of histological lesions in patients with antibodies to hepatitis C virus

1997 • 267 citations

Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.

1997 • 256 citations

Diagnostic accuracy of hyaluronan and type III procollagen amino-terminal peptide serum assays as markers of liver fibrosis in chronic viral hepatitis C evaluated by ROC curve analysis

1996 • 242 citations

Measurement of serum hyaluronic acid in patients with chronic hepatitis C and its relationship to liver histology

2000 • 234 citations

Role of liver biopsy in management of chronic hepatitis C: A systematic review

2002 • 210 citations

Interobserver study of liver histopathology using the Ishak score in patients with chronic hepatitis C virus infection

1999 • 208 citations

Noninvasive monitoring of patients with chronic hepatitis C

2002 • 203 citations

UK guidelines on the management of variceal haemorrhage in cirrhotic patients

2000 • 201 citations

Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis

2001 • 200 citations

Plasma clearance of intravenously injected aspartate aminotransferase isozymes: Evidence for preferential uptake by sinusoidal liver cells

1985 • 177 citations

Aspartate aminotransferase : alanine aminotransferase ratio in chronic hepatitis C infection: Is it a useful predictor of cirrhosis?

2000 • 173 citations

Serum Thrombopoietin Levels in Patients With Chronic Hepatitis and Liver Cirrhosis

1999 • 144 citations

Serum Activity of Mitochondrial Aspartate Aminotransferase: A Sensitive Marker of Alcoholism With or Without Alcoholic Hepatitis

1984 • 139 citations

Need for validation of clinical decision aids: use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C

2000 • 111 citations

Combination of interferon and ribavirin in chronic hepatitis C: Re-treatment of nonresponders to interferon

2001 • 105 citations

AST/ALT ratio > or = 1 is not diagnostic of cirrhosis in patients with chronic hepatitis C.

1998 • 83 citations

Development and validation of a model to diagnose cirrhosis in patients with hepatitis C

2002 • 56 citations

Randomized, placebo‐controlled, double‐blind trial with interferon‐α with and without amantadine sulphate in primary interferon‐α nonresponders with chronic hepatitis C

2001 • 36 citations

Importance of age in chronic hepatitis C virus infection

1997 • 33 citations

Daily or three times per week interferon α-2b in combination with ribavirin or interferon alone for the treatment of patients with chronic hepatitis C not responding to previous interferon alone

2002 • 19 citations

Hepatology highlights

2002 • 8 citations