Validity and Clinical Utility of the Aspartate Aminotransferase–Alanine Aminotransferase Ratio in Assessing Disease Severity and Prognosis in Patients With Hepatitis C Virus–Related Chronic Liver Disease

Transection of the oesophagus for bleeding oesophageal varices

1973 • 7,698 citations

A model to predict survival in patients with end-stage liver disease

2001 • 4,580 citations

Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis

1999 • 1,610 citations

Classification of chronic viral hepatitis: a need for reassessment

1991 • 1,526 citations

Estimating future hepatitis C morbidity, mortality, and costs in the United States

2000 • 582 citations

Variability of hepatitis C virus

1995 • 561 citations

AST/ALT Ratio Predicts Cirrhosis in Patients With Chronic Hepatitis C Virus Infection

1998 • 516 citations

Ratio of Serum Aspartate to Alanine Aminotransferase in Chronic Hepatitis Relationship to Cirrhosis

1988 • 497 citations

The SGOT/SGPT ratio?An indicator of alcoholic liver disease

1979 • 446 citations

The Ratio of Aspartate Aminotransferase to Alanine Aminotransferase: Potential Value in Differentiating Nonalcoholic Steatohepatitis From Alcoholic Liver Disease

1999 • 438 citations

Diagnosis and Monitoring of Hepatic Injury. II. Recommendations for Use of Laboratory Tests in Screening, Diagnosis, and Monitoring

2000 • 429 citations

The role of liver biopsy in chronic hepatitis C

2002 • 354 citations

Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study

1994 • 305 citations

Factors associated with serum alanine transaminase activity in healthy subjects: Consequences for the definition of normal values, for selection of blood donors, and for patients with chronic hepatitis C

1998 • 298 citations

Clinical use of serum enzymes in liver disease

1988 • 277 citations

The role of liver biopsy in chronic hepatitis C

2001 • 273 citations

Utility of a discriminant score for diagnosing advanced fibrosis or cirrhosis in patients with chronic hepatitis C virus infection.

1997 • 256 citations

A peek at the child-turcotte classification

1981 • 248 citations

Natural history of hepatitis C

1999 • 243 citations

Progressive liver functional impairment is associated with an increase in AST/ALT ratio.

1999 • 205 citations

Risk Factors for the Presence of Varices in Cirrhotic Patients Without a History of Variceal Hemorrhage

2001 • 179 citations

Plasma clearance of intravenously injected aspartate aminotransferase isozymes: Evidence for preferential uptake by sinusoidal liver cells

1985 • 177 citations

Aspartate aminotransferase : alanine aminotransferase ratio in chronic hepatitis C infection: Is it a useful predictor of cirrhosis?

2000 • 173 citations

Relationship of aminotransferases to liver histological status in chronic hepatitis C.

1995 • 158 citations

Need for validation of clinical decision aids: use of the AST/ALT ratio in predicting cirrhosis in chronic hepatitis C

2000 • 111 citations

Costs of Hepatitis C

2001 • 109 citations

An assessment of the clinical utility of serum ALT and AST in chronic hepatitis C

2000 • 99 citations

AST/ALT ratio > or = 1 is not diagnostic of cirrhosis in patients with chronic hepatitis C.

1998 • 83 citations

The significance of baseline serum alanine aminotransferase on pretreatment disease characteristics and response to antiviral therapy in chronic hepatitis C

2000 • 75 citations

Serum aspartate but not alanine aminotransferase levels help to predict the histological features of chronic hepatitis c viral infections in adults

2000 • 66 citations

Monoethylglycinexylidide formation measurement as a hepatic function test to assess severity of chronic liver disease.

1997 • 45 citations

Elevated SGOT/SGPT ratio in alcoholic patients with acetaminophen hepatotoxicity.

1984 • 40 citations

The serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase ratio as a prognostic index in severe acute viral hepatitis.

1982 • 38 citations

Thrombocytopenia associated with liver cirrhosis and hepatitis C viral infection: role of thrombopoietin.

2000 • 31 citations

Transportability and reproducibility of the AST/ALT ratio in chronic hepatitis C patients

2001 • 21 citations

Validation of a discriminant score for the diagnosis of cirrhosis in patients with chronic hepatitis

2000 • 8 citations