The Use of Cell Markers in The Study of Human Hematopoietic Neoplasia
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Abstract
References (211)
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Immunoglobulin-Gene Rearrangements as Unique Clonal Markers in Human Lymphoid Neoplasms
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Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.
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Lineage promiscuity in hemopoietic differentiation and leukemia
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Clonal origin of chronic myelocytic leukemia in man.
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A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes
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Agnogenic myeloid metaplasia: a clonal proliferation of hematopoietic stem cells with secondary myelofibrosis
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The Epstein-Barr Virus
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Restriction Endonucleases in the Analysis and Restructuring of DNA Molecules
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Polymorphic diffuse B-cell hyperplasias and lymphomas in renal transplant recipients.
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Glucose-6-Phosphate Dehydrogenase Mosaicism: Utilization as a Cell Marker in the Study of Leiomyomas
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Immunoglobulins on the Surface of Neoplastic Lymphocytes
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Use of Restriction Fragment Length Polymorphisms to Determine the Clonal Origin of Human Tumors
1985 • 387 citations
Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell
1981 • 385 citations
Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.
1983 • 385 citations
Rearrangements of Genes for the Antigen Receptor on T Cells as Markers of Lineage and Clonality in Human Lymphoid Neoplasms
1985 • 367 citations
Hairy Cell Leukemia
1978 • 350 citations
Clonal Rearrangements of T-Cell Receptor Genes in Mycosis Fungoides and Dermatopathic Lymphadenopathy
1985 • 349 citations
REARRANGEMENT OF THE T-CELL-RECEPTOR $beta;-CHAIN GENE IN THE DIAGNOSIS OF LYMPHOPROLIFERATIVE DISORDERS
1985 • 333 citations
Chronic Myelocytic Leukemia
1978 • 332 citations
Evidence for a multistep pathogenesis of chronic myelogenous leukemia
1981 • 331 citations
Monoclonality of Lymphoproliferative Lesions in Cardiac-Transplant Recipients
1984 • 305 citations
Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.
1984 • 305 citations
Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture, 1982)
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Karnofsky Memorial Lecture. Marrow transplantation for malignant diseases.
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1981 • 259 citations
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1985 • 257 citations
Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man
1982 • 255 citations
Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.
1979 • 255 citations
Age and Sleep
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When to Eat
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T-cell receptor gene rearrangements as markers of lineage and clonality in T-cell neoplasms.
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Involvement of the B-lymphoid system in chronic myelogenous leukaemia
1980 • 240 citations
CYTOGENETIC STUDIES IN CHRONIC MYELOID LEUKÆMIA AND ACUTE LEUKAÆMIA ASSOCIATED WITH MONGOLISM
1961 • 229 citations
Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.
1984 • 226 citations
Lymphoid Blast Crises of Chronic Myelogenous Leukemia Represent Stages in the Development of B-Cell Precursors
1983 • 215 citations
Acute nonlymphocytic leukemia: heterogeneity of stem cell origin
1981 • 215 citations
Biclonal B-Cell Lymphoma
1984 • 212 citations
Primordial cell pool size and lineage relationships of five human cell types*
1973 • 210 citations
Hemizygous Expression of Glucose-6-Phosphate Dehydrogenase in Erythrocytes of Heterozygotes for the Lesch-Nyhan Syndrome
1970 • 209 citations
LYMPHOPROLIFERATIVE DISORDERS IN CARDIAC TRANSPLANT RECIPIENTS ARE MULTICLONAL LYMPHOMAS
1984 • 209 citations
The Origin and Development of Human Tumors Studied with Cell Markers
1974 • 208 citations
T gamma-lymphoproliferative disease and related disorders in humans and experimental animals: a review of the clinical, cellular, and functional characteristics
1984 • 200 citations
Rearrangement of the Gene for the Beta Chain of the T-Cell Receptor in T-Cell Chronic Lymphocytic Leukemia and Related Disorders
1985 • 200 citations
Epstein–Barr Virus–Associated B-Cell Proliferations of Diverse Clonal Origins after Bone Marrow Transplantation in a 12-Year-Old Patient with Severe Combined Immunodeficiency
1985 • 198 citations
Membrane Markers in “Histiocytic” Lymphomas (Reticulum Cell Sarcomas) 2
1976 • 196 citations
Expression of the Gene Defect in X-Linked Agammaglobulinemia
1986 • 177 citations
Monoclonal lymphocyte population in human plasma cell myeloma.
1974 • 173 citations
IMMUNOGLOBULIN AND GLUCOSE-6-PHOSPHATE DEHYDROGENASE AS MARKERS OF CELLULAR ORIGIN IN BURKITT LYMPHOMA
1973 • 167 citations
T-cell surface antigens in a patient with blast crisis of chronic myeloid leukemia
1983 • 167 citations
Acute Nonlymphocytic Leukemia
1979 • 161 citations
The Epstein-Barr virus in the pathogenesis of posttransplant lymphoproliferative disorders. Clinical, pathologic, and virologic correlation.
1981 • 160 citations
T-Cell Lymphoproliferative Syndrome Associated with Human T-Cell Leukemia/Lymphoma Virus
1984 • 160 citations
Growth characteristics of leukemic and normal hematopoietic cells in Ph' + chronic myelogenous leukemia and effects of intensive treatment
1982 • 159 citations
Polycythemia vera. The in vitro response of normal and abnormal stem cell lines to erythropoietin.
1978 • 154 citations
T gamma-lymphoproliferative disease and related disorders in humans and experimental animals: a review of the clinical, cellular, and functional characteristics
1984 • 153 citations
The Human T-Cell Receptor
1985 • 152 citations
Immunoglobulins on the Surface of Lymphoid Cells in Waldenström's Macroglobulinemia
1972 • 147 citations
Pathogenesis of B cell lymphoma in a patient with AIDS
1986 • 146 citations
DISORDERS OF THE CHEST
1947 • 145 citations
Genomic diversity correlates with clinical variation in Ph′-negative chronic myeloid leukaemia
1986 • 145 citations
Nonrandom chromosomal abnormalities in hematologic disorders of man.
1975 • 144 citations
Rearrangement of the T-Cell Receptor β-Chain Gene in Non-T-Cell, Non-B-Cell Acute Lymphoblastic Leukemia of Childhood
1985 • 144 citations
Chromosomes and causation of human cancer and leukemiaXVI. Banding studies of chronic myelocytic leukemia, including five unusual Ph1translocations
1975 • 142 citations
LEUKÆMIC TRANSFORMATION OF ENGRAFTED HUMAN MARROW CELLS IN VIVO
1972 • 139 citations
The phenotype of the neoplastic cells of hairy cell leukemia studied with monoclonal antibodies
1982 • 136 citations
Restriction fragment length polymorphisms as markers of engraftment in allogeneic marrow transplantation
1985 • 135 citations
Characteristics of blast crisis in chronic granulocytic leukemia
1977 • 128 citations
Same Idiotypc of B‐Lymphocyte Membrane IgD and IgM. Formal Evidence for Monoclonality of Chronic Lymphocytic Leukemia Cells
1974 • 127 citations
Origin of Human Bone Marrow Fibroblasts
1980 • 124 citations
Normal human B cells display ordered light chain gene rearrangements and deletions.
1982 • 124 citations
A monoclonal immunoblastic sarcoma in donor cells bearing Epstein-Barr virus genomes following allogeneic marrow grafting for acute lymphoblastic leukemia
1982 • 119 citations
Origin of Chronic Myelocytic Leukemia in a Precursor of Pre-B Lymphocytes
1979 • 113 citations
T cell receptor beta chain gene rearrangements in lymphoproliferative disorders of large granular lymphocytes/natural killer cells.
1985 • 113 citations
The Monoclonal Nature of Lymphocytes in Multiple Myeloma
1975 • 107 citations
Cytogenetics of preleukemia
1982 • 105 citations
Use Of Genetic Markers To Study Cellular Origin And Development Of Tumors In Human Females
1972 • 103 citations
The incidence of recurrence of leukemia in donor cells after allogeneic bone marrow transplantation
1982 • 102 citations
Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.
1980 • 101 citations
Membrane marker and cell separation studies in Ph1-positive leukemia
1978 • 101 citations
CLASS, SUBCLASS, AND ALLELIC EXCLUSION OF MEMBRANE-BOUND Ig OF HUMAN B LYMPHOCYTES
1972 • 100 citations
Cytogenetic evidence for recurrence of acute myelogenous leukemia after allogeneic bone marrow transplantation in donor hematopoietic cells
1978 • 97 citations
Richter's syndrome with different immunoglobulin light chains and different heavy chain gene rearrangements
1984 • 96 citations
Wiskott-Aldrich syndrome: cellular impairments and their implication for carrier detection
1980 • 96 citations
Evidence for the involvement of B lymphoid cells in polycythemia vera and essential thrombocythemia.
1985 • 96 citations
Biologic and prognostic significance of the presence of more than two mu heavy-chain genes in childhood acute lymphoblastic leukemia of B precursor cell origin
1986 • 95 citations
ALLELIC EXCLUSION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN PLATELETS AND T LYMPHOCYTES FROM A WISKOTT-ALDRICH SYNDROME CARRIER
1980 • 95 citations
Circulating Monoclonal B Lymphocytes in Non-Hodgkin's Lymphoma
1984 • 91 citations
Incidence of involvement of the B and T lymphocyte lineages in chronic myelogenous leukemia
1985 • 88 citations
Immunoblastic Sarcoma in Donor Cells after Bone-Marrow Transplantation
1979 • 85 citations
Recurrence of Ph′-Positive Leukemia in Donor Cells after Marrow Transplantation for Chronic Granulocytic Leukemia
1984 • 85 citations
A Clonal Complete Remission in a Patient with Acute Nonlymphocytic Leukemia Originating in a Multipotent Stem Cell
1984 • 82 citations
Spontaneous Alteration of Idiotype in a Monoclonal B-Cell Lymphoma
1985 • 81 citations
Immunoglobulin gene rearrangements in remission bone marrow specimens from patients with acute lymphoblastic leukemia
1986 • 81 citations
Molecular Genetic Analysis of Human Lymphoid Neoplasms
1985 • 80 citations
T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia
1986 • 79 citations
In vivo leukemic transformation: Cytogenetic evidence of in vivo leukemic transformation of engrafted marrow cells
1977 • 78 citations
Leukemia Relapse in Donor Cells after Allogeneic Bone-Marrow Transplantation
1981 • 73 citations
Donor cell leukemia developing six years after marrow grafting for acute leukemia
1985 • 73 citations
An immunoglobulin heavy-chain gene is altered in two T-cell clones
1980 • 72 citations
Detection of clonal excess in lymphoproliferative disease by kappa/lambda analysis: correlation with immunoglobulin gene DNA rearrangement
1986 • 71 citations
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosome
1980 • 70 citations
Different stages of B cell differentiation in non-T acute lymphoblastic leukemia.
1984 • 70 citations
CHRONIC LYMPHOCYTIC LEUKÆMIA: CLONAL ORIGIN IN A COMMITTED B-LYMPHOCYTE PROGENITOR
1978 • 69 citations
Philadelphia chromosome positive blood B lymphocytes in chronic myelocytic leukemia
1981 • 69 citations
Late-appearing Philadelphia chromosome in two patients with chronic myelogenous leukemia
1980 • 69 citations
Analysis of T-cell receptor beta chain (T beta) gene rearrangements demonstrates the monoclonal nature of T-cell chronic lymphoproliferative disorders.
1986 • 68 citations
Cytogenetic studies of early myeloid progenitor compartments in Ph1- positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients
1984 • 67 citations
The heterogeneity of leukemic reticuloendotheliosis, “hairy cell leukemia”. Evidence for its monocytic origin
1976 • 67 citations
Chromosome Pattern of Bone Marrow Fibroblasts in Patients with Chronic Granulocytic Leukaemia
1969 • 64 citations
Cytogentics of fibroblastic colonies in Ph1-positive chronic myelogenous leukemia
1978 • 63 citations
Probable clonal origin of acute myeloblastic leukemia following radiation and chemotherapy of colon cancer.
1978 • 62 citations
Heterogeneity of morphological, cytochemical, and cytogenetic features in the blastic phase of chronic granulocytic leukemia
1975 • 62 citations
Human erythroid colony formation in vitro: Evidence for clonal origin
1976 • 62 citations
Evidence for a stem cell common to hematopoiesis and its in vitro microenvironment: Studies of patients with clonal hematopoietic neoplasia
1984 • 61 citations
Direct evidence for presence of Ph-1 chromosome in erythroid cells.
1968 • 60 citations
Epstein-Barr virus in a malignant lymphoproliferative disorder of B-cells occurring after thymic epithelial transplantation for combined immunodeficiency.
1981 • 59 citations
Clonal Origin of the Philadelphia Chromosome and Chronic Myeloid Leukaemia: Evidence from a Sex Chromosome Mosaic
1971 • 59 citations
Chronic myelocytic leukemia (CML): failure to detect residual normal committed stem cells in vitro
1979 • 59 citations
Cytogentics of fibroblastic colonies in Ph1-positive chronic myelogenous leukemia
1978 • 59 citations
T cells and probably B cells arise from the malignant clone in chronic myelogenous leukemia.
1985 • 59 citations
Cytogenetic studies of early myeloid progenitor compartments in Ph1‐positive chronic myeloid leukaemia (CML) I. PERSISTENCE OF Ph1‐NEGATIVE COMMITTED PROGENITORS THAT ARE SUPPRESSED FROM DIFFERENTIATING IN VIVO
1984 • 58 citations
Evidence for clonal development of childhood acute lymphoblastic leukemia
1985 • 58 citations
Regulation of the Immune Response by Idiotypic-Antiidiotypic Interactions
1981 • 58 citations
The immunoglobulin μ constant region gene is expressed in mouse thymocytes
1980 • 58 citations
Variable breakpoints on the Philadelphia chromosome in chronic myelogenous leukemia
1985 • 58 citations
IDIOTYPIC UNIFORMITY OF CELL SURFACE IMMUNOGLOBULIN IN CHRONIC LYMPHOCYTIC LEUKEMIA
1974 • 57 citations
Involvement of the Erythroid Series in Blastic Crisis of Chronic Myeloid Leukaemia. FURTHER EVIDENCE FOR THE PRESENCE OF PHILADELPHIA CHROMOSOME IN ERYTHROBLASTS
1966 • 57 citations
Cell surface localized IgM-kappa immunoglobulin reactivity in a case of chronic lymphocytic leukaemia.
1970 • 55 citations
B-lymphoid cell involvement in chronic myelogenous leukemia: Implications for the pathogenesis of the disease
1982 • 55 citations
Absence of mosaicism in the lymphocyte in X-linked congenital hyperuricosuria
1968 • 54 citations
Chronic myeloid leukemia with permanent disappearance of the Ph1 chromosome and development of new clonal subpopulations
1979 • 54 citations
Pancytopenia as a clonal disorder of a multipotent hematopoietic stem cell.
1984 • 52 citations
Primary thrombocythemia: clonal origin of platelets, erythrocytes, and granulocytes in a GdB/GdMediterranean subject
1982 • 51 citations
Immunoglobulin synthesis and glucose-6-phosphate dehydrogenase as cell markers in human lymphoblastoid cell lines*1
1974 • 51 citations
ALPHA-CHAIN DISEASE: EVIDENCE FOR COMMON CLONAL ORIGIN OF INTESTINAL IMMUNOBLASTIC LYMPHOMA AND PLASMACYTIC PROLIFERATION
1977 • 49 citations
Clonal rearrangement and expression of the T cell receptor beta gene and involvement of the breakpoint cluster region in blast crisis of CGL
1986 • 48 citations
Leukaemic transformation of engrafted bone marrow cells
1985 • 48 citations
Nonclonal hemopoietic progenitor cells detected in long-term marrow cultures from a Turner syndrome mosaic with chronic myeloid leukemia
1984 • 46 citations
Unicellular or multicellular origin of human granulocyte-macrophage colonies in vitro
1979 • 45 citations
Cytogenetic studies of early myeloid progenitor compartments in Ph1- positive chronic myeloid leukemia. II. Long-term culture reveals the persistence of Ph1-negative progenitors in treated as well as newly diagnosed patients
1984 • 45 citations
HYBRIDIZATION OF TWO BIOCHEMICALLY MARKED HUMAN CELL LINES
1969 • 43 citations
Circulating pluripotent haemopoietic cells in patients with myeloproliferative disorders
1983 • 42 citations
In vitro Hybridization of Normal and Variant Human Glucose-6-phosphate Dehydrogenase
1967 • 41 citations
Gd(-) Abrami a deficient G-6PD variant with hemizygous expression in blood cells of a woman with primary myelofibrosis
1975 • 40 citations
Non-random chromosome gains in human lymphoblastoid cell lines
1977 • 40 citations
Philadelphia chromosome (Ph1)-negative chronic myelogenous leukemia (CML): a clonal disease with origin in a multipotent stem cell
1980 • 39 citations
T cell lineage involvement in lymphoid blast crisis of chronic myeloid leukemia
1985 • 38 citations
Recent advances in hematology
1966 • 37 citations
Clonal Origin of the Philadelphia Chromosome From Either the Paternal or the Maternal Chromosome Number 22
1974 • 37 citations
The mutual clonal origin of the lymphoplasmocytic and lymphoma cell in alpha-heavy chain disease.
1977 • 37 citations
Chronic myelogenous leukemia in the monosomic cell line of a fertile turner syndrome mosaic (45,X/46,XX)
1982 • 37 citations
Chronic myelocytic leukemia: eosinophils involved in the malignant clone
1980 • 37 citations
Ph1-positive T lymphoblastic transformation
1984 • 36 citations
Viral “Tumorigenesis” in man: Cell markers in condylomata acuminata
1976 • 35 citations
The human c-abl oncogene in the philadelphia translocation
1984 • 35 citations
Heterogeneity of B cell involvement in acute nonlymphocytic leukemia
1985 • 33 citations
SECOND MALIGNANT CLONE UNDERLYING A BURKITT-TUMOUR EXACERBATION
1972 • 33 citations
The Origin of Bone Marrow Fibroblasts
1973 • 33 citations
6-Phosphogluconate Dehydrogenase: Hemizygous Manifestation in a Patient with Leukemia
1969 • 32 citations
The Philadelphia (Ph) chromosome in leukemia. II. Variant Ph translocations in acute lymphoblastic leukemia
1985 • 31 citations
Cellular events in the differentiation of antibody-secreting cells.
1984 • 30 citations
Additional c-abl/bcr rearrangements in a CML patient exhibiting two Ph1 chromosomes during blast crisis
1986 • 30 citations
Contemporary Hematology/Oncology
1980 • 29 citations
Detection of two distinct malignant B cell clones in a single patient using anti-idiotype monoclonal antibodies and immunoglobulin gene rearrangement
1985 • 26 citations
Preleukemias
1981 • 26 citations
Single or multicellular origin of human T lymphocyte colonies in vitro: modification by 12-o-tetradecanoylphorbol 13-acetate (TPA).
1981 • 25 citations
Ph1 positive blast crisis of chronic myeloid leukaemia exhibiting features characteristic of early T blasts
1984 • 25 citations
Reexpression of normal stem cells in erythroleukemia during remission
1983 • 24 citations
Chronic myelogenous leukemia: Prolonged survival with spontaneous decline in the frequency of Ph1-positive cells and subsequent development of mixed Ph1-positive and Ph1-negative blast crisis
1983 • 23 citations
Is there a precursive, relatively procoagulant-inactive form of normal antihemophilic factor (factor VIII)?
1979 • 22 citations
Patient with chronic myelogenous leukemia and late appearing Philadelphia chromosome
1982 • 21 citations
Lymphoid crisis with T‐cell phenotypes in a patient with Philadelphia chromosome negative chronic myeloid leukaemia
1985 • 20 citations
Clonal origin of cells restricted to monocytic differentiation in acute nonlymphocytic leukemia
1984 • 20 citations
G6PD isoenzyme analysis of myeloid and lymphoid cells in human multilineage colonies
1984 • 19 citations
On the Monoclonal Origin of Chronic Myelocytic Leukemia
1974 • 17 citations
Chronic myelogenous leukemia with a complex Ph1 translocation in an XYY male
1984 • 17 citations
ON " A KEY POINT OF MODERN BIOCHEMICAL GENETICS "
1963 • 17 citations
Human mixed cell colonies: unicellular or multicellular origin–analysis by G-6-PD
1984 • 16 citations
Additional chromosomal indication for the unicellular origin of chronic myelocytic leukemia
1975 • 13 citations
Monoclonal immunoglobulin-secreting lymphoma in a patient with severe combined immunodeficiency disease.
1982 • 12 citations
Clonal origin of the Philadelphia translocation in chronic myeloid leukemia demonstrated in somatic cell hybrids using an adenylate kinase-1 polymorphism
1982 • 12 citations
Detection of the blastic crisis cell clone in chronic myeloid leukaemia
1985 • 12 citations
Molecular evidence for the clonal origin of blast crisis in chronic myeloid leukaemia
1986 • 8 citations
Confirming evidence for the clonal development and stem cell origin of philadelphia chromosome‐negative chronic myelogenous leukemia
1984 • 7 citations
Human mixed cell colonies: unicellular or multicellular origin–analysis by G-6-PD
1984 • 7 citations
E rosette‐positive agar colonies containing the Philadelphia chromosome in chronic myeloid leukaemia
1985 • 6 citations
Clonal development from a progenitor with restricted differentiative expression in acute lymphoblastic leukemia
1985 • 6 citations
Deleted Work
1955 • 0 citations
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