Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Monoclonal Antibodies Defining Distinctive Human T Cell Surface Antigens

1979 • 1,480 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

Commentary: “The Role of T3 Surface Molecules in the Activation of Human Cells: A Two-Stimulus Requirement for IL-2 Production Reflects Events Occurring at a Pretranslational Level”

2015 • 572 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line.

1984 • 504 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.

1984 • 455 citations

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.

1984 • 452 citations

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

1984 • 380 citations

Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit

1985 • 303 citations

The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

1984 • 290 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex

1984 • 232 citations

Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.

1985 • 225 citations

The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium.

1985 • 223 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

1983 • 209 citations

The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans

1984 • 204 citations

Tolerance of T-cell clones is associated with membrane antigen changes

1983 • 187 citations

Rearrangements of T-cell receptor gene YT35 in human DNA from thymic leukaemia T-cell lines and functional T-cell clones

1984 • 124 citations

Identification of a diversity segment of human T-cell receptor β-chain, and comparison with the analogous murine element

1984 • 121 citations

The δ- and ε-chains of the human T3/T-cell receptor complex are distinct polypeptides

1984 • 113 citations

Biosynthesis and molecular nature of the T3 antigen of human T lymphocytes.

1983 • 110 citations

Complete nucleotide sequence of an infectious clone of Friend spleen focus-forming provirus: gp55 is an envelope fusion glycoprotein.

1983 • 109 citations

Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes.

1984 • 107 citations

Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen.

1983 • 101 citations

The T3 complex on human thymus‐derived lymphocytes contains two different subunits of 20 kDa

1983 • 99 citations

Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production

1983 • 78 citations

T cell receptor alpha chain genes are located on chromosome 14 at 14q11-14q12 in humans.

1985 • 77 citations

Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex.

1984 • 49 citations

Nucleotide sequences of the murine retrovirus Friend SFFVp long terminal repeats: identification of a structure with extensive dyad symmetry 5′ to the TATA box

1982 • 36 citations

Genes Encoding the Human T Cell Antigen Receptor

1984 • 34 citations

Stereospecificity of the Escherichia coli valyl-RNA synthetase in the ATP-32PPi exchange reaction

1968 • 20 citations