Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

DNA Modification Mechanisms and Gene Activity During Development

1975 • 1,859 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

X inactivation, differentiation, and DNA methylation

1975 • 1,283 citations

Effects of methylation on a synthetic polynucleotide: the B--Z transition in poly(dG-m5dC).poly(dG-m5dC).

1981 • 873 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation

1981 • 711 citations

The Role of X-Chromosome Inactivation during Spermatogenesis

1972 • 508 citations

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

1983 • 404 citations

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

1982 • 295 citations

Selective Silencing of Eukaryotic DNA

1975 • 224 citations

Unusual methylation pattern of the α2(I) collagen gene

1982 • 177 citations

Studies of X chromosome DNA methylation in normal human cells

1982 • 157 citations

Regional assignment of the steroid sulfatase—X-linked ichthyosis locus: Implications for a noninactivated region on the short arm of human X chromosome

1979 • 150 citations

Transformation with DNA from 5-azacytidine-reactivated X chromosomes.

1982 • 149 citations

Direct identification of sickle cell anemia by blot hybridization.

1981 • 148 citations

Differences in the DNA of the inactive X chromosomes of fetal and extraembryonic tissues of mice

1983 • 123 citations

The effect of sequence specific DNA methylation on restriction endonuclease cleavage

1981 • 120 citations

Overlap hybridization screening: Isolation and characterization of overlapping DNA fragments surrounding the leu2 gene on yeast chromosome III

1979 • 113 citations

Derepression of genes on the human inactive X chromosome: Evidence for differences in locus-specific rates of derepression and rates of transfer of active and inactive genes after DNA-mediated transformation

1982 • 110 citations

Inactive X chromosome DNA does not function in DNA-mediated cell transformation for the hypoxanthine phosphoribosyltransferase gene.

1980 • 106 citations

Isolation and Properties of Deoxyribonucleic Acid from Mammalian Sperm

1961 • 101 citations

Mammalian X-Chromosome Inactivation

1976 • 97 citations

Expression of an X-linked gene from an inactive human X chromosome in mouse-human hybrid cells: further evidence for the noninactivation of the steroid sulfatase locus in man.

1980 • 95 citations

Identification of a sequence responsible for periodic synthesis of yeast histone 2A mRNA.

1982 • 83 citations

Mammalian Gonadal Determination and Gametogenesis

1981 • 62 citations

Quantitation of mRNAs during mouse spermatogenesis: protamine-like histone and phosphoglycerate kinase-2 mRNAs increase after meiosis.

1980 • 61 citations

Evidence for DNA modification in the maintenance of X-chromosome inactivation of adult mouse tissues.

1982 • 54 citations

Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome.

1982 • 48 citations

Is DNA methylation responsible for mammalian X chromosome inactivation?

1982 • 28 citations

Transformation ofHprt gene with sperm DNA

1983 • 12 citations