VEGF induces cardiovascular malformation and embryonic lethality.

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Monoclonal Antibody to 5-Bromo- and 5-Iododeoxyuridine: A New Reagent for Detection of DNA Replication

1982 • 2,648 citations

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.

1989 • 1,282 citations

Blood Vessel Formation: What Is Its Molecular Basis?

1996 • 1,242 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure

1997 • 831 citations

Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development

1995 • 546 citations

Vasculogenesis in the early quail blastodisc as studied with a monoclonal antibody recognizing endothelial cells

1987 • 533 citations

VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane

1997 • 501 citations

Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization.

1995 • 338 citations

A previously undescribed congenital malformation of the heart: almost total absence of the myocardium of the right ventricle.

1952 • 274 citations

Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor 2(flk-1) Are Expressed during Vasculogenesis and Vascular Differentiation in the Quail Embryo

1995 • 270 citations

Overexpression of Vascular Endothelial Growth Factor in the Avian Embryo Induces Hypervascularization and Increased Vascular Permeability without Alterations of Embryonic Pattern Formation

1995 • 222 citations

Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development

1993 • 209 citations

Microvascular Permeability of Albumin, Vascular Surface Area, and Vascular Volume Measured in Human Adenocarcinoma LS174T Using Dorsal Chamber in SCID Mice

1993 • 207 citations

Angiogenic potential of the avian somite

1995 • 170 citations

In vivo effects of vascular endothelial growth factor on the chicken chorioallantoic membrane

1993 • 148 citations

VEGF121Induces Proliferation of Vascular Endothelial Cells and Expression offlk-1without Affecting Lymphatic Vessels of the Chorioallantoic Membrane

1996 • 139 citations

Expression of the avian VEGF receptor homologues Quek1 and Quek2 in blood-vascular and lymphatic endothelial and non-endothelial cells during quail embryonic development

1997 • 114 citations

The effects of growth factors on the day 13 chorioallantoic membrane (CAM): a study of VEGF165 and PDGF-BB

1992 • 87 citations

Uhl's anomaly.

1979 • 67 citations

Parchment heart (Osler)

1950 • 66 citations

Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells

1993 • 66 citations

Molecular cloning of Quek 1 and 2, two quail vascular endothelial growth factor (VEGF) receptor-like molecules

1996 • 52 citations

Synthesis and physiological activity of heterodimers comprising different splice forms of vascular endothelial growth factor and placenta growth factor

1996 • 49 citations

Congenital hypoplasia of portions of both right and left ventricular myocardial walls

1980 • 44 citations

Kinetics and differentiation of somite cells forming the vertebral column: studies on human and chick embryos

1994 • 34 citations

Case 38201

1952 • 17 citations

Macromolecular permeability of chick wing microvessels: an intravital confocal study

1995 • 2 citations