The cell of origin in Hodgkin's disease.

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells

1985 • 1,817 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease

1989 • 917 citations

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

1982 • 878 citations

[Hodgkin's disease].

1988 • 829 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

Epstein-Barr viral DNA in tissues of Hodgkin's disease.

1987 • 520 citations

Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men

1983 • 517 citations

On Some Morbid Appearances of the Absorbent Glands and Spleen

1832 • 500 citations

The Approaching Era of the Tumor Suppressor Genes

1987 • 468 citations

Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma.

1984 • 464 citations

Identification of Hodgkin and sternberg‐reed cells as a unique cell type derived from a newly‐detected small‐cell population

1982 • 421 citations

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.

1984 • 400 citations

Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types

1985 • 382 citations

The human met oncogene is related to the tyrosine kinase oncogenes

1985 • 295 citations

Demonstration of a Herpes Group Virus in Cultures of Peripheral Leukocytes from Patients with Infectious Mononucleosis

1968 • 269 citations

Lymphoid tumors displaying rearrangements of both immunoglobulin and T cell receptor genes.

1985 • 267 citations

Leu M1 and Peanut Agglutinin Stain the Neoplastic Cells of Hodgkin’s Disease

1984 • 265 citations

Uniform Detection of Immunoglobulin-Gene Rearrangement in Benign Lymphoepithelial Lesions

1987 • 230 citations

Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia

1990 • 220 citations

A Survey of Epstein-Barr Virus DNA in Lymphoid Tissue: Frequent Detection in Hodgkin’s Disease

1989 • 219 citations

Immunoglobulin and T-cell receptor gene rearrangements in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma: Dissociation between phenotype and genotype

1989 • 210 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia

1987 • 201 citations

Reed-Sternberg and Hodgkin Cells in Lymphocyte-Predominant Hodgkin’s Disease of Nodular Subtype Contain J Chain

1986 • 184 citations

Hemopoietic lineage switch: v-raf oncogene converts Eμmyc transgenic B cells into macrophages

1988 • 179 citations

Hodgkin and sternberg‐reed cells contain antigens specific to late cells of granulopoiesis

1982 • 175 citations

Cytochemical, immunologic, chromosomal, and molecular genetic analysis of a novel cell line derived from Hodgkin's disease

1986 • 171 citations

Immunoglobulin and T-cell receptor beta-chain gene rearrangement analysis of Hodgkin's disease: implications for lineage determination and differential diagnosis.

1986 • 166 citations

Heavy chain immunoglobulin gene rearrangement in acute nonlymphocytic leukemia

1984 • 163 citations

Two neoplastic cell lines with unique features derived from Hodgkin's disease

1980 • 159 citations

Characteristics of Hodgkin's disease-derived cell lines.

1982 • 153 citations

Interleukin-6 immunoreactivity in human tumors.

1989 • 136 citations

T cell receptor and immunoglobulin gene rearrangements in acute myeloblastic leukemia.

1986 • 135 citations

The structure of the T cell antigen receptor genes in normal and malignant T cells

1986 • 133 citations

REED-STERNBERG-LIKE CELLS IN INFECTIOUS MONONUCLEOSIS

1969 • 129 citations

Autologous Mixed Lymphocyte Reaction in Patients with Hodgkin's Disease

1980 • 126 citations

The immunophenotype of reed-sternberg cells. A study of 50 cases of Hodgkin' disease using fixed frozen tissues

1989 • 126 citations

Genotypic analysis of large cell lymphomas which express the Ki‐1 antigen

1987 • 120 citations

Ferritin, a Hodgkin's Disease Associated Antigen

1974 • 112 citations

Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1.

1988 • 111 citations

Expression of lymphoid‐associated antigens on Hodgkin's and Reed‐Sternberg cells of Hodgkin's disease. An immunocytochemical study on lymph node cytospins using monoclonal antibodies

1987 • 106 citations

Epstein–Barr virus transforms precursor B cells even before immunoglobulin gene rearrangements

1984 • 105 citations

Morphologic, immunologic, enzymehistochemical and chromosomal analysis of a cell line derived from Hodgkin's disease. Evidence for a B-cell origin of sternberg-reed cells

1985 • 93 citations

Evaluation of ricin A chain-containing immunotoxins directed against the CD30 antigen as potential reagents for the treatment of Hodgkin's disease.

1990 • 89 citations

Immunophenotypes of Reed-Sternberg cells: a study of 19 cases of Hodgkin's disease in plastic-embedded sections

1989 • 84 citations

Chromosomal abnormalities in Hodgkin's disease

1989 • 80 citations

Cytogenetic features of Hodgkin's disease suggest possible origin from a lymphocyte

1988 • 78 citations

Chromosome findings in effusions from patients with Hodgkin's disease

1978 • 74 citations

Epstein‐Barr virus‐transformed human precursor B cell lines: altered growth phenotype of lines with germline or rearranged but nonexpressed heavy chain genes

1987 • 73 citations

Phenotype versus immunoglobulin and T‐cell receptor genotype of Hodgkin‐derived cell lines: Activation of immature lymphoid cells in Hodgkin's disease

1987 • 71 citations

Interrelations of the histologic types of Hodgkin's disease.

1971 • 70 citations

L-428 nodular sclerosing Hodgkin's cell secretes a unique transforming growth factor-beta active at physiologic pH.

1988 • 69 citations

Neoplastic cells obtained from Hodgkin's disease are potent stimulators of human primary mixed lymphocyte cultures.

1983 • 63 citations

Unique display of a pathologic karyotype in Hodgkin's disease by Reed-Sternberg cells

1988 • 59 citations

Molecular pathways of adhesion in spontaneous rosetting of T-lymphocytes to the Hodgkin's cell line L428.

1988 • 58 citations

SUP-HD1: a new Hodgkin's disease-derived cell line with lymphoid features produces interferon-gamma [see comments]

1989 • 53 citations

Chromosomes in Hodgkin's disease.

1982 • 51 citations

Cytogenetic investigations in Hodgkin's disease: I. Involvement of specific chromosomes in marker formation

1986 • 50 citations

Polyclonal 90yttrium labeled antiferritin for refractory Hodgkin's disease

1989 • 49 citations

Aberrant expression of T cell and B cell markers in myelocyte/monocyte/histiocyte-derived lymphoma and leukemia cells. Is the infrequent expression of T/B cell markers sufficient to establish a lymphoid origin for Hodgkin's Reed-Sternberg cells?

1989 • 47 citations

Chromosomal Abnormalities in Hodgkin’s Disease

1989 • 46 citations

ras Oncogenes and the molecular mechanisms of carcinogenesis

1984 • 41 citations

Phenotypic and genotypic analysis of Hodgkin's disease derived cell lines: histopathological and clinical implications.

1985 • 40 citations

Heterogeneity of interleukin 1 production in cultured Reed-Sternberg cell lines HDLM-1, HDLM-1d, and KM-H2.

1989 • 39 citations

The Hodgkin-Associated Ki-1 Antigen Exists in an Intracellular and a Membrane-Bound Form

1989 • 38 citations

Hodgkin and Reed-Sternberg cell associated monoclonal antibodies HRS-1 and HRS-2 react with activated cells of lymphoid and monocytoid origin.

1988 • 38 citations

Effect of a herpes group virus (EBV) on growth of peripheral leukocyte cultures

1969 • 37 citations

Hodgkin's disease, lymphocyte-predominant type: immunoreactivity with B-cell antibodies.

1988 • 37 citations

DNA aneuploidy in Hodgkin's disease. A multiparameter flow-cytometric analysis with cytologic correlation.

1987 • 34 citations

Expression ofc-myc Oncogens Product andras Family Oncogene Products in Various Human Malignant Lymphomas Defined by Immunohistochemical Techniques

1988 • 32 citations

Genotypes and immunophenotypes of Hodgkin's disease-derived cell lines.

1988 • 32 citations

Secondary activation of c-abl may be related to translocation to the nucleolar organizer region in an in vitro cultured rat leukemia cell line (K3D).

1986 • 27 citations

Isolation of activated ras transforming genes from two patients with Hodgkin's disease

1985 • 25 citations

Human granulocyte-macrophage colony-stimulating factor purified from a Hodgkin's tumor cell line

1986 • 24 citations

The nature of the hodgkin cell

1988 • 22 citations

Rearrangements of chromosomal regions containing ribosomal RNA genes and centromeric heterochromatin in the human melanoma cell line MeWo

1986 • 21 citations

Hodgkin's cell lectin, a lymphocyte adhesion molecule and mitogen.

1989 • 20 citations

Effect of neonatal sympathectomy by 6-hydroxydopamine on renal hemodynamic parameters in adult rats

1985 • 20 citations

Immunology of Hodgkin and Reed-Sternberg Cells

1989 • 19 citations

Anti-Leu-3a antibody reactivity with Reed-Sternberg cells of Hodgkin's disease.

1988 • 17 citations

Analysis of Immunoglobulin, T Cell Receptor and bcr Rearrangements in Human Malignant Lymphoma and Hodgkin’s Disease

1990 • 16 citations

Immunologic, functional and moleculargenetic properties of Hodgkin-derived cell lines

1988 • 13 citations

Cytogenetic studies of Hodgkin's disease

1989 • 13 citations

Stability of multiple antigen receptor gene rearrangements and immunophenotype in Hodgkin's disease-derived cell line L428 and variant subline L428KSA.

1989 • 12 citations

Inhibition of human neutrophil migration by supernatants from Hodgkin's disease‐derived cell lines

1988 • 11 citations

Chromosomal in situ hybridization of a Hodgkin's disease-derived cell line (L540) using DNA probes for TCRA, TCRB, MET, and rRNA

1990 • 11 citations

Pathology of Hodgkin’s Disease: Anything New?

1989 • 10 citations

Radiolabeled Monoclonal Antibodies Against Reed-Sternberg Cells for in Vivo Imaging of Hodgkin’s Disease by Immunoscintigraphy

1989 • 6 citations

Comments on Hodgkin's disease: the Sternberg-Reed cell by P. Bucsky

1988 • 6 citations

Biology of Hodgkin Cell Lines

1989 • 5 citations

Expression of High Affinity IL-2 Receptors on a Hodgkin Cell Line

1990 • 2 citations

Epstein-Barr Virus (EBV) in Lymphoid Cells from Patients with Hodgkin’s Disease

1974 • 2 citations

A New Hypothesis on the Cellular Origin of Reed-Sternberg and Hodgkin Cells Based on the Immunological and Molecular Genetic Analysis of the KM-H2 Line

1989 • 2 citations