Phenotype versus immunoglobulin and T‐cell receptor genotype of Hodgkin‐derived cell lines: Activation of immature lymphoid cells in Hodgkin's disease

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Somatic generation of antibody diversity

1983 • 3,275 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells

1985 • 1,817 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Identification of a putative second T-cell receptor

1986 • 980 citations

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

1982 • 878 citations

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1982 • 877 citations

Characterization of EBV‐genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non‐Hodgkin lymphoma

1977 • 698 citations

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

1981 • 576 citations

Distinctive functional characteristics of human „T”︁ lymphocytes defined by E rosetting or a monoclonal anti‐T cell antibody

1981 • 498 citations

Identification of Hodgkin and sternberg‐reed cells as a unique cell type derived from a newly‐detected small‐cell population

1982 • 421 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types

1985 • 382 citations

Clustered arrangement of immunoglobulin λ constant region genes in man

1981 • 379 citations

Rearrangements of Genes for the Antigen Receptor on T Cells as Markers of Lineage and Clonality in Human Lymphoid Neoplasms

1985 • 367 citations

Human immunoglobulin κ light-chain genes are deleted or rearranged in λ-producing B cells

1981 • 332 citations

A uniform deleting element mediates the loss of κ genes in human B cells

1985 • 259 citations

T-Cell Receptor Gene Rearrangements as Clinical Markers of Human T-Cell Lymphomas

1985 • 258 citations

A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.

1985 • 238 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.

1985 • 225 citations

Diazotizable arylamine cellulose papers for the coupling and hybridization of nucleic acids

1982 • 218 citations

Immunoglobulin class switching

1984 • 208 citations

Use of freeze-dried paraffin-embedded sections for immunohistologic staining with monoclonal antibodies.

1985 • 208 citations

Exogenous Immunoglobulin and the Macrophage Origin of Reed–Sternberg Cells in Hodgkin's Disease

1978 • 180 citations

Rearrangement of the beta chain of the T cell antigen receptor and immunoglobulin genes in lymphoproliferative disorders.

1986 • 166 citations

Immunoglobulin and T-cell receptor beta-chain gene rearrangement analysis of Hodgkin's disease: implications for lineage determination and differential diagnosis.

1986 • 166 citations

Hodgkin's disease: Establishment and characterization of four in vitro cell lines

1981 • 162 citations

Two neoplastic cell lines with unique features derived from Hodgkin's disease

1980 • 159 citations

Novel κ light-chain gene rearrangements in mouse λ light chain-producing B lymphocytes

1984 • 157 citations

Deletion of the Nontransforming Epstein-Barr Virus Strain P3HR-1 Causes Fusion of the Large Internal Repeat to the DS _L Region

1982 • 145 citations

IMMUNOHISTOCHEMICAL DEMONSTRATION OF IgG IN REED-STERNBERG AND OTHER CELLS IN HODGKIN'S DISEASE

1974 • 143 citations

T cell receptor and immunoglobulin gene rearrangements in acute myeloblastic leukemia.

1986 • 135 citations

Immunoglobulin gene organisation and expression in haemopoietic stem cell leukaemia.

1983 • 112 citations

Immunoglobulin heavy-chain class switching in a pre-B cell line is accompanied by DNA rearrangement

1983 • 105 citations

The complexity of immunohistochemical staining pattern of hodgkin and sternberg‐reed cells—demonstration of immunoglobulin, albumin, α₁‐antichymotrypsin and lysozyme

1978 • 103 citations

Monocyte/macrophage-specific monoclonal antibody Ki-M1 recognizes interdigitating reticulum cells.

1984 • 93 citations

IMMUNOGLOBULIN-POSITIVE REED-STERNBERG CELLS IN HODGKIN'S DISEASE

1973 • 87 citations

Evidence for the detection of the normal counterpart of hodgkin and sternberg‐reed cells

1983 • 82 citations

Comparison of the hinge-coding segments in human immunoglobulin gamma heavy chain genes and the linkage of the gamma 2 and gamma 4 subclass genes.

1982 • 65 citations

Epstein-Barr virus-positive Burkitt's lymphoma in a german woman during pregnancy

1980 • 64 citations

Diversity of immunoglobulin expression in leukaemic cells resembling B-lymphocyte precursors

1981 • 60 citations

Characterization of immunoglobulins in Hodgkin cells

1977 • 59 citations

Phenotypic analysis of an established cell line derived from a patient with Hodgkin's disease (HD)

1985 • 59 citations

Isotype switching in murine pre-B cell lines

1983 • 55 citations

Cytogenetic investigations in Hodgkin's disease: I. Involvement of specific chromosomes in marker formation

1986 • 50 citations

The construction of cosmid libraries of eukaryotic DNA using the Homer series of vectors

1982 • 40 citations

Hodgkin and sternberg‐reed cell antigen(S) detected by an antiserum to a cell line (L428) derived from Hodgkin's disease

1981 • 36 citations

No evidence for differences in the Epstein-Barr virus genome carried in Burkitt lymphoma cells and nonmalignant lymphoblastoid cells from the same patients.

1984 • 33 citations

Internal mammary lymphoscintigraphy: Current status in the treatment of breast cancer

1983 • 25 citations

Translocation t(8;22) in peripheral lymphocytes and established lymphoid cell lines from a patient with Hodgkin's disease followed by acute lymphatic leukemia

1982 • 20 citations

Monoclonals and DNA Probes in Diagnostic and Preventive Medicine

1988 • 13 citations