Expression ofc-myc Oncogens Product andras Family Oncogene Products in Various Human Malignant Lymphomas Defined by Immunohistochemical Techniques

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

National cancer institute sponsored study of classifications of non-hodgkin's lymphomas. Summary and description of a working formulation for clinical usage

1982 • 3,027 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

1983 • 921 citations

Expression of Cellular Oncogenes in Human Malignancies

1984 • 840 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Cellular Transforming Genes

1982 • 622 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Translocation and Rearrangements of the c- myc Oncogene Locus in Human Undifferentiated B-Cell Lymphomas

1983 • 514 citations

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells.

1984 • 502 citations

Transcriptional activation of the translocated c- myc oncogene in Burkitt lymphoma

1983 • 340 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

1983 • 286 citations

Expression of a Cellular Oncogene During Liver Regeneration

1983 • 281 citations

Expression ofrasOncogene p21 in Prostate Cancer

1986 • 269 citations

Mutations in N-ras predominate in acute myeloid leukemia

1987 • 239 citations

Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene

1983 • 236 citations

Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases

1984 • 226 citations

Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas.

1984 • 223 citations

V-myc- and c-myc-encoded proteins are associated with the nuclear matrix.

1985 • 222 citations

A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient.

1984 • 207 citations

ras gene Amplification and malignant transformation.

1985 • 204 citations

Frequency of molecular alterations affecting ras protooncogenes in human urinary tract tumors.

1985 • 191 citations

ras Oncogene p21 expression is increased in premalignant lesions and high grade bladder carcinoma.

1985 • 173 citations

Mutation Affecting the 12th Amino Acid of the c-Ha- ras Oncogene Product Occurs Infrequently in Human Cancer

1983 • 162 citations

Expression of the 21,000 molecular weight ras protein in a spectrum of benign and malignant human mammary tissues.

1986 • 140 citations

Expression of p21 ras oncoproteins in human cancers.

1986 • 119 citations

Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells.

1985 • 117 citations

Spontaneous activation of a human proto-oncogene.

1983 • 114 citations

Molecular cloning of avian myelocytomatosis virus (MC29) transforming sequences.

1981 • 100 citations

Somatic Activation of ras ^K Gene in a Human Ovarian Carcinoma

1984 • 97 citations

Amplified expression of p21 ras protein in hormone-dependent mammary carcinomas of humans and rodents

1985 • 94 citations

Enhanced expression of c-Ha-ras p21 in human stomach adenocarcinomas defined by immunoassays using monoclonal antibodies and in situ hybridization.

1987 • 74 citations

The Emerging Genetics of Human Cancer

1983 • 55 citations

Growth factors and oncogenes

1985 • 55 citations

ONCOGENES

1983 • 37 citations

Alteration of the genomes of tumor cells

1983 • 28 citations

Structure and Biological Activity of the Amplified c-myc Gene in a Transplantable Human Gastric Cancer1

2015 • 6 citations