Metabolic compartmentation and substrate channelling in muscle cells
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Abstract
References (267)
ATP-regulated K+ channels in cardiac muscle
1983 • 2,350 citations
The Respiratory Chain and Oxidative Phosphorylation
1956 • 2,073 citations
Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis
1992 • 1,958 citations
Role of calcium ions in regulation of mammalian intramitochondrial metabolism
1990 • 1,369 citations
The Enzymes of Biological Membranes
1985 • 1,362 citations
The heart and cardiovascular system
1986 • 1,333 citations
Regulation of Metabolic Processes in Mitochondria
1967 • 1,182 citations
Effect of pressure development on oxygen consumption by isolated rat heart
1967 • 1,099 citations
RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION
1955 • 1,089 citations
COMPLEXES OF SEQUENTIAL METABOLIC ENZYMES
1987 • 1,019 citations
The binding change mechanism for ATP synthase — Some probabilities and possibilities
1993 • 1,006 citations
Cytosolic phosphorylation potential.
1979 • 906 citations
Respiratory Enzymes in Oxidative Phosphorylation
1958 • 900 citations
How crowded is the cytoplasm?
1982 • 807 citations
Transport of Energy in Muscle: The Phosphorylcreatine Shuttle
1981 • 748 citations
THE CREATINE-CREATINE PHOSPHATE ENERGY SHUTTLE
1985 • 746 citations
OXIDATIVE PHOSPHORYLATIONS: RÔLE OF INORGANIC PHOSPHATE AND ACCEPTOR SYSTEMS IN CONTROL OF METABOLIC RATES
1952 • 744 citations
Effects of pH and free Mg2+ on the Keq of the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions.
1979 • 602 citations
Control of respiration and ATP synthesis in mammalian mitochondria and cells
1992 • 598 citations
Regulation of Glucose Uptake in Muscle
1961 • 595 citations
Role of glycolytic products in damage to ischemic myocardium. Dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts.
1984 • 572 citations
The Conduction of the Nervous Impulse
1965 • 538 citations
Ionic Mobility in Muscle Cells
1969 • 510 citations
A linear model of muscle respiration explains monoexponential phosphocreatine changes
1988 • 506 citations
A simple analysis of the "phosphocreatine shuttle"
1984 • 503 citations
Creatine Kinase of Rat Heart Mitochondria
1973 • 467 citations
Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism
1992 • 439 citations
Regulation of cellular energy metabolism
1982 • 433 citations
Regulation of oxidative phosphorylation in the mammalian cell
1990 • 432 citations
Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man
1992 • 394 citations
Glycolysis Preferentially Inhibits ATP-Sensitive K + Channels in Isolated Guinea Pig Cardiac Myocytes
1987 • 391 citations
Relation Between Work and Phosphate Metabolite in the in Vivo Paced Mammalian Heart
1986 • 383 citations
Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function.
1985 • 379 citations
Molecular and physiological aspects of adenine nucleotide trasport in mitochondria
1976 • 373 citations
Relation between mitochondrial calcium transport and control of energy metabolism
1985 • 362 citations
The release of calcium from heart mitochondria by sodium
1974 • 353 citations
Compartmentation and Communication in Living Systems. Ligand Conduction: a General Catalytic Principle in Chemical, Osmotic and Chemiosmotic Reaction Systems
1979 • 349 citations
Mitochondrial respiratory parameters in cardiac tissue: A novel method of assessment by using saponin-skinned fibers
1987 • 342 citations
High activity of creatine kinase in mitochondria from muscle and brain and evidence for a separate mitochondrial isoenzyme of creatine kinase
1964 • 341 citations
Control of mitochondrial ATP synthesis in the heart
1991 • 333 citations
Properties and metabolism of the aqueous cytoplasm and its boundaries
1984 • 320 citations
Functional compartmentation of ATP and creatine phosphate in heart muscle
1970 • 301 citations
Role of creatine phosphokinase in cellular function and metabolism
1978 • 298 citations
ADP/ATP carrier protein from beef heart mitochondria has high amounts of tightly bound cardiolipin, as revealed by phosphorus-31 nuclear magnetic resonance
1985 • 296 citations
Reaction rates of creatine kinase and ATP synthesis in the isolated rat heart. A 31P NMR magnetization transfer study.
1985 • 286 citations
Membrane protein oligomeric structure and transport function
1981 • 277 citations
Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts.
1985 • 264 citations
Intracellular diffusion gradients of O2 and ATP
1986 • 261 citations
On the role of organized multienzyme systems in cellular metabolism: A general synthesis
1978 • 261 citations
The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart
1972 • 258 citations
Multiple controls of oxidative metabolism in living tissues as studied by phosphorus magnetic resonance.
1986 • 256 citations
Regulation of oxygen consumption in fast- and slow-twitch muscle
1992 • 253 citations
Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart.
1985 • 249 citations
Relation between phosphate metabolites and oxygen consumption of heart in vivo
1989 • 249 citations
Studies of Energy Transport in Heart Cells. Mitochondrial Isoenzyme of Creatine Phosphokinase: Kinetic Properties and Regulatory Action of Mg2+ Ions
1975 • 245 citations
Respiratory Control and the Integration of Heart High-Energy Phosphate Metabolism by Mitochondrial Creatine Kinase
1985 • 241 citations
Ultrastructural, functional, and biochemical criteria for estimation of reversibility of ischemic injury: A study on the effects of global ischemia on the isolated dog heart
1979 • 240 citations
First-order kinetics of muscle oxygen consumption, and an equivalent proportionality between QO2 and phosphorylcreatine level. Implications for the control of respiration.
1985 • 233 citations
Concentrations of Metabolites and Binding Sites. Implications in Metabolic Regulation
1970 • 228 citations
Membrane Bioenergetics
1988 • 227 citations
Mechanisms of ischemic myocardial cell damage assessed by phosphorus-31 nuclear magnetic resonance.
1982 • 212 citations
Membrane-bound ATP fuels the Na/K pump. Studies on membrane-bound glycolytic enzymes on inside-out vesicles from human red cell membranes.
1981 • 210 citations
Muscle-type MM creatine kinase is specifically bound to sarcoplasmic reticulum and can support Ca2+ uptake and regulate local ATP/ADP ratios.
1990 • 207 citations
Energetics of muscular contraction.
1969 • 198 citations
Effects of increased heart work on glycolysis and adenine nucleotides in the perfused heart of normal and diabetic rats
1971 • 197 citations
Adenine nucleotide metabolism and compartmentalization in isolated adult rat heart cells.
1984 • 189 citations
Creatine kinase of rat heart mitochondria. The demonstration of functional coupling to oxidative phosphorylation in an inner membrane-matrix preparation.
1985 • 186 citations
Phosphorus nuclear magnetic resonance spectroscopy of cardiac and skeletal muscles
1982 • 185 citations
The ADP-ATP Carrier in Mitochondrial Membranes
1976 • 181 citations
Studies of controlled reperfusion after ischemia
1990 • 181 citations
Regulation of the oxidative phosphorylation rate in the intact cell
1990 • 177 citations
The role of protein fluctuations in enzyme action: A review
1982 • 175 citations
Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts.
1990 • 174 citations
The regulation of ATP‐sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes.
1990 • 170 citations
Native mitochondrial creatine kinase forms octameric structures. I. Isolation of two interconvertible mitochondrial creatine kinase forms, dimeric and octameric mitochondrial creatine kinase: characterization, localization, and structure-function relationships.
1988 • 167 citations
The Role of Compartmentation in the Control of Glycolysis
1977 • 164 citations
A 31P-NMR saturation transfer study of the regulation of creatine kinase in the rat heart
1982 • 164 citations
Adenosine triphosphate compartmentation in living hearts: a phosphorus nuclear magnetic resonance saturation transfer study
1979 • 162 citations
The possible role of the mitochondrial bound creatine kinase in regulation of mitochondrial respiration
1966 • 158 citations
Studies of energy transport in heart cells. The importance of creatine kinase localization for the coupling of mitochondrial phosphorylcreatine production to oxidative phosphorylation.
1980 • 158 citations
Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia.
1991 • 153 citations
Regulation of Glucose Uptake in Muscle
1961 • 151 citations
A relationship between adenosine triphosphate, glycolysis and ischaemic contracture in the isolated rat heart
1981 • 151 citations
In vivo regulation of mitochondrial respiration in cardiomyocytes: specific restrictions for intracellular diffusion of ADP
1991 • 150 citations
The Organization of Cell Metabolism
1986 • 149 citations
Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia.
1990 • 149 citations
The cationically selective state of the mitochondrial outer membrane pore: a study with intact mitochondria and reconstituted mitochondrial porin
1990 • 147 citations
A fuzzy subsarcolemmal space for intracellular Na+ in cardiac cells?
1992 • 146 citations
Respiratory control in the glucose perfused heart
1987 • 141 citations
Measurement of an individual rate constant in the presence of multiple exchanges: application to myocardial creatine kinase reaction
1986 • 140 citations
Cardiolipin is the membrane receptor for mitochondrial creatine phosphokinase.
1985 • 140 citations
Control of Mitochondrial Respiration in the Heart In Vivo
1990 • 134 citations
Retarded diffusion of ADP in cardiomyocytes: possible role of mitochondrial outer membrane and creatine kinase in cellular regulation of oxidative phosphorylation
1993 • 134 citations
Cytoskeleton
1988 • 129 citations
Energy relationships between cytosolic metabolism and mitochondrial respiration in rat heart
1978 • 127 citations
Regulating ATP turnover rates over broad dynamic work ranges in skeletal muscles
1992 • 127 citations
Creatine kinase of heart mitochondria: Changes in its kinetic properties induced by coupling to oxidative phosphorylation
1982 • 126 citations
Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart.
1987 • 125 citations
Cytosolic adenylates and adenosine release in perfused working heart
1986 • 123 citations
Compartmentalized ATP synthesis in skeletal muscle triads
1992 • 121 citations
In Search of the physical basis of life
1986 • 120 citations
The localization of mitochondrial creatine kinase, and its use for the determination of the sidedness of submitochondrial particles
1973 • 119 citations
Ruthenium Red inhibits the activation of pyruvate dehydrogenase caused by positive inotropic agents in the perfused rat heart
1983 • 119 citations
Studies of energy transport in heart cells
1976 • 118 citations
Respiratory control in isolated perfused rat heart. Role of the equilibrium relations between the mitochondrial electron carriers and the adenylate system
1975 • 118 citations
Analysis of metabolic control: new insights using scaled creatine kinase model
1988 • 117 citations
The Mechanochemistry of Muscular Contraction
1960 • 117 citations
In Search of the Physical Basis of Life
1984 • 116 citations
Mitochondrial Function in the Heart
1979 • 114 citations
31P‐NMR studies of respiratory regulation in the intact myocardium
1986 • 111 citations
Reconstitution of adenine nucleotide transport from beef heart mitochondria
1979 • 110 citations
Mechanism of ischemic contracture in ferret hearts: relative roles of [Ca2+]i elevation and ATP depletion
1990 • 109 citations
The localization of the MM isozyme of creatine phosphokinase on the surface membrane of myocardial cells and its functional coupling to ouabain-inhibited (Na+,K+)-ATPase
1977 • 108 citations
Effects of cardiac work on electrical potential gradient across mitochondrial membrane in perfused rat hearts
1993 • 107 citations
ATP concentration gradients in cytosol of liver cells during hypoxia
1985 • 106 citations
Guanidino compounds in biology and medicine
1992 • 105 citations
Linear dependence of muscle phosphocreatine kinetics on total creatine content
1989 • 105 citations
On the triple localization of creatine kinase in heart and skeletal muscle cells of the rat: Evidence for the existence of myofibrillar and mitochondrial isoenzymes
1973 • 104 citations
In situ compartmentation of creatine kinase in intact sarcomeric muscle: The acto-myosin overlap zone as a molecular sieve
1992 • 104 citations
Profiles of creatine kinase isoenzyme compositions in single muscle fibres of different types
1991 • 103 citations
Functional coupling between sarcoplasmic‐reticulum‐bound creatine kinase and Ca2+‐ATPase
1993 • 103 citations
Nuclear magnetic resonance studies of cellular metabolism
1990 • 102 citations
Functional characterization of mitochondrial oxidative phosphorylation in saponin-skinned human muscle fibers
1993 • 102 citations
Stimulation of K-C1 cotransport in rat red cells by a hemolytic anemia-producing metabolite of dapsone
1989 • 101 citations
The cytoplasmic phosphorylation potentialIts possible role in the control of myocardial respiration and cardiac contractility
1985 • 100 citations
Regional Energy Metabolism of Failing Hearts Following Myocardial Infarction
1993 • 99 citations
In vivo flux between phosphocreatine and adenosine triphosphate determined by two-dimensional phosphorous NMR.
1983 • 97 citations
Coordination of citric acid cycle activity with electron transport flux.
1976 • 97 citations
Regulation of creatine kinase during steady-state isometric twitch contraction in rat skeletal muscle
1984 • 96 citations
The Functional Recovery of Post-Ischemic Myocardium Requires Glycolysis During Early Reperfusion
1993 • 96 citations
Organized Multienzyme Systems: Catalytic Properties
1985 • 95 citations
The effects of ruthenium red on mitochondrial function during post-ischaemic reperfusion
1982 • 95 citations
Ischemic contracture begins when anaerobic glycolysis stops: a 31P-NMR study of isolated rat hearts
1991 • 95 citations
Regulation of oxidative phosphorylation in mitochondria by external free Ca2+ concentrations.
1985 • 94 citations
Cardiac metabolism--emergence, decline, and resurgence. Part II.
1992 • 94 citations
Microenvironments and metabolic compartmentation
1978 • 94 citations
Control of heart mitochondrial oxygen consumption by creatine kinase: The importance of enzyme localization
1982 • 92 citations
The Effect of 2,4-Dinitrofluorobenzene on the Activity of Striated Muscle
1965 • 92 citations
Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation
1990 • 91 citations
Regulation of energy flux through the creatine kinase reaction in vitro and in perfused rat heart
1984 • 84 citations
Direct evidence for a role of intramitochondrial Ca2+ in the regulation of oxidative phosphorylation in the stimulated rat heart. Studies using31P n.m.r. and ruthenium red
1989 • 84 citations
Kinetic properties and the functional role of particulate MM‐isoenzyme of creatine phosphokinase bound to heart muscle myofibrils
1976 • 83 citations
Quantitative 31P nuclear magnetic resonance analysis of metabolite concentrations in Langendorff-perfused rabbit hearts
1985 • 83 citations
STUDIES OF CONTROLLED REPERFUSION AFTER ISCHEMIA
1986 • 82 citations
Metabolic Control and the Microenvironment
1977 • 81 citations
The cardiac contractile failure induced by chronic creatine and phosphocreatine deficiency
1988 • 80 citations
The Heart and Cardiovascular System: Scientific Foundations.
1987 • 77 citations
Subcellular distribution of phosphagens in isolated perfused rat heart
1980 • 76 citations
Role of phosphocreatine in energy transport in skeletal muscle of bullfrog studied by 31P-NMR
1990 • 76 citations
Compartmentation of Adenine Nucleotides in the Isolated Working Guinea Pig Heart Stimulated by Noradrenaline
1981 • 76 citations
Advances in Myocardiology
1985 • 76 citations
Formation of creatine phosphate from creatine and 32P-labelled ATP by isolated rabbit heart mitochondria
1977 • 75 citations
Bioenergetic consequences of cardiac phosphocreatine depletion induced by creatine analogue feeding.
1991 • 74 citations
Sustained function of normoxic hearts depleted in ATP and phosphocreatine: a 31P-NMR study
1988 • 74 citations
The ADP/ATP Carrier in Mitochondrial Membranes
1985 • 70 citations
Mitochondrial respiratory control in the myocardium
1986 • 70 citations
Relationship of phosphorylation potential and oxygen consumption in isolated perfused rat hearts
1980 • 70 citations
Pathophysiology of Severe Ischemic Myocardial Injury
1990 • 70 citations
An electron microscopic histochemical investigation of the localization of creatine phosphokinase in heart cells
1977 • 69 citations
Voltage gating of the mitochondrial outer membrane channel VDAC is regulated by a very conserved protein
1991 • 69 citations
Supramolecular organization of glycolytic enzymes
1985 • 68 citations
Intracellular compartmentalization of adenosine triphosphate.
1986 • 68 citations
Effects of norepinephrine infusion on myocardial high-energy phosphate content and turnover in the living rat.
1987 • 68 citations
Reversible MM-creatine kinase binding to cardiac myofibrils
1987 • 67 citations
The role of microcompartmentation in the regulation of glutamate metabolism by rat kidney mitochondria.
1980 • 66 citations
Creatine kinase as an intracellular regulator
1984 • 66 citations
Insulin uptake and processing by cultured mouse glomerular endothelial cells
1993 • 65 citations
Energy transport from mitochondria to myofibril by a creatine phosphate shuttle in cardiac cells
1983 • 64 citations
Coordinate interplay between (Na+ + K+)-ATPase and creatine phosphokinase optimizes (Na+/K+)-antiport across the membrane of vesicles formed from the plasma membrane of cardiac muscle cell
1980 • 62 citations
Phosphocreatine pathway for energy transport: ADP diffusion and cardiomyopathy
1991 • 62 citations
Specific enhancement of the cardiac myofibrillar ATPase by bound creatine kinase.
1992 • 62 citations
Cellular Infrastructure and Metabolic Organization
1992 • 61 citations
Topography of the membrane-bound ADP/ATP carrier assessed by enzymic proteolysis
1992 • 61 citations
Effect of creatine kinase activity on mitochondrial ADP/ATP transport. Evidence for a functional interaction.
1984 • 60 citations
Nuclear magnetic resonance evaluation of metabolic and respiratory support of work load in intact rabbit hearts.
1992 • 60 citations
Velocity of the creatine kinase reaction in the neonatal rabbit heart: role of mitochondrial creatine kinase
1988 • 60 citations
Contact sites between inner and outer mitochondrial membrane
1990 • 60 citations
Compartmentation of mitochondrial creatine phosphokinase. II. The importance of the outer mitochondrial membrane for mitochondrial compartmentation.
1982 • 60 citations
Quantitative evaluation of relationship between cardiac energy metabolism and post-ischemic recovery of contractile function
1989 • 59 citations
The structure of mitochondrial membranes: A new concept
1978 • 59 citations
Study of energy transport mechanism in myocardial cells.
1974 • 59 citations
NMR Studies of Metabolism
1990 • 57 citations
Saturation and inversion transfer studies of creatine kinase kinetics in rabbit skeletal muscle in vivo
1988 • 56 citations
Rebound recovery of myocardial creatine phosphate with reperfusion after ischemia
1984 • 56 citations
Dynamics of biochemical systems
1988 • 55 citations
Activation of dehydrogenase activity and cardiac respiration: a 31P-NMR study
1988 • 55 citations
Mitochondrial creatine kinase activity alterations in skeletal muscle during long-distance running
1986 • 55 citations
Application of pulsed-gradient 31P NMR on frog muscle to measure the diffusion rates of phosphorus compounds in cells
1982 • 53 citations
Analysis of compartmentation of ATP in skeletal and cardiac muscle using 31P nuclear magnetic resonance saturation transfer
1987 • 52 citations
The Role of Creatine Phosphokinase in Supplying Energy for the Calcium Pump System of Heart Sarcoplasmic Reticulum
1978 • 52 citations
A role for water in cell structure
1987 • 52 citations
Role of glycolytic flux in effect of glucose in decreasing fatty-acid-induced release of lactate dehydrogenase from isolated coronary ligated rat heart
1979 • 52 citations
Postischaemic reperfusion injury in the isolated rat heart: effect of ruthenium red
1991 • 51 citations
Cardiac metabolism - emergence, decline, and resurgence. Part I
1992 • 51 citations
[Identification of human porins. II. Characterization and primary structure of a 31-lDa porin from human B lymphocytes (Porin 31HL)].
1989 • 50 citations
Heart mitochondrial creatine kinase revisited: The outer mitochondrial membrane is not important for coupling of phosphocreatine production to oxidative phosphorylation
1989 • 49 citations
Metabolite status of the heart in acute insufficiency due to 1-fluoro-2,4-dinitrobenzene
1968 • 49 citations
Identification and primary structure of the cardiolipin‐binding domain of mitochondrial creatine kinase
1988 • 48 citations
Regulation of the mitochondrial outer membrane channel, VDAC
1987 • 47 citations
Influence of the mitochondrial outer membrane and the binding of creatine kinase to the mitochondrial inner membrane on the compartmentation of adenine nucleotides in the intermembrane space of rat heart mitochondria
1993 • 46 citations
Specific inhibition of ATP-ADP translocase in cardiac mitoplasts by antibodies against mitochondrial creatine kinase
1987 • 46 citations
The anaerobic activity of the isolated frog's heart
1932 • 46 citations
Supramolecular enzyme organization : quaternary structure and beyond
1984 • 45 citations
Ca,Mg-ATPase activity of permeabilised rat heart cells and its functional coupling to oxidative phosphorylation of the cells
1988 • 45 citations
Detection of Exchange Reactions Involving Small Metabolite Pools Using NMR Magnetization Transfer Techniques: Relevance to Subcellular Compartmentation of Creatine Kinase
1985 • 45 citations
Effect of inotropic stimulation on mitochondrial calcium in cardiac muscle.
1992 • 45 citations
Membranes creatine kinase (E. C. 2. 7. 3. 2.) in pig heart mitochondriaProperties and role in phosphate potential regulation
1972 • 44 citations
On the mechanochemistry of muscular contraction
1972 • 42 citations
Dissociation of adenosine triphosphate levels and contractilefunction in isovolumic hearts perfused with 2-deoxyglucose
1987 • 42 citations
Regulation of Mitochondrial Activity in Cardiac Cells
1985 • 41 citations
NMR-Invisible ATP in Rat Heart and Its Change in Ischemia1
1988 • 40 citations
Control, bioenergetics, and adaptation in health and disease: noninvasive biochemistry from nuclear magnetic resonance
1992 • 39 citations
Quantitative analysis of the ‘phosphocreatine shuttle’: I. A probability approach to the description of phosophocreatine production in the coupled creatine kinase-ATP/ADP translocase-oxidative phosphorylation reactions in heart mitochondria
1993 • 39 citations
31P NMR Studies of the Kinetics and Regulation of Oxidative Phosphorylation in the Intact Myocardiuma
1987 • 39 citations
Affinity modification of creatine kinase and ATP-ADP translocase in heart mitochondria: Determination of their molar stoichiometry
1986 • 39 citations
Catalytic Facilitation and Membrane Bioenergetics
1985 • 38 citations
Cytoplasmic Cellular Structures Control Permeability of Outer Mitochondrial-Membrane for ADP and Oxidative-Phosphorylation in Rat-Liver Cells
1995 • 38 citations
Compartmentation of creatine kinase isoenzymes in myometrium of gravid guinea‐pig.
1993 • 37 citations
Compartmentation of K+ in isolated adult rat heart cells
1981 • 37 citations
Reversible modulation of the mitochondrial ATP synthase with energy demand in cultured rat cardiomyocytes
1989 • 36 citations
Respiratory control and substrate effects in the working rat heart
1992 • 35 citations
Organization of Proteins within the Mitochondrion
1985 • 35 citations
Histochemistry of creatine phosphokinase
1976 • 34 citations
Association of chicken mitochondrial creatine kinase with the inner mitochondrial membrane
1987 • 34 citations
Dynamic Compartmentation in Soluble Multienzyme Systems
1985 • 31 citations
Alterations in the creatine kinase system in the myocardium of cardiomyopathic hamsters
1989 • 31 citations
Heart Creatine Kinase, The Integration of Isozymes for Energy Distribution
1981 • 31 citations
The role of multienzyme complexes in integration of cellular metabolism
1986 • 30 citations
The Aqueous Cytoplasm
1979 • 29 citations
Estimation of heart mitochondrial creatine kinase flux using magnetization transfer NMR spectroscopy
1992 • 28 citations
Mitochondrial oxidative phosphorylation in saponin‐skinned human muscle fibers is stimulated by caffeine
1993 • 28 citations
Determination of free creatine and phosphocreatine concentrations in the isolated perfused rat heart by 1H- and 31P-NMR
1992 • 28 citations
The role of the mitochondriial creatine kinase system for myocardial function during ischemia and reperfusion
1992 • 27 citations
Control of mitochondrial respiration in muscle
1988 • 25 citations
Sodium pump failure in hypoxia and reoxygenation
1992 • 24 citations
Die Bedeutung von Kreatinphosphat und Adenosintriphosphat im Hinblick auf Energiebereitstellung, -transport und -verwertung im normalen und insuffizienten Herzmuskel
1970 • 23 citations
Importance of the mitochondrial outer membrane channel as a model biological channel
1987 • 23 citations
Regulation of fatty acid utilization in heart. Role of the carnitine-acetyl-CoA transferase and carnitine-acetyl carnitine translocase system
1982 • 22 citations
Compartmentation of ATP within renal proximal tubular cells
1984 • 22 citations
Mitochondrial dehydrogenase activity affects adaptation of cardiac oxygen consumption to demand
1993 • 21 citations
A synthetic functional metabolic compartment
1987 • 21 citations
Proposed Knobs-Into-Holes Packing for Several Membrane Proteins
1978 • 21 citations
Subcellular restricted spaces: significance for cell signalling and excitation-contraction coupling
1993 • 21 citations
CONTROL OF HEART OXIDATIVE PHOSPHORYLATION BY CREATINE KINASE IN MITOCHONDRIAL MEMBRANES*
1983 • 20 citations
On the organization and diffusion of glycolytic enzymes in skeletal muscle.
1989 • 19 citations
The mechanism of respiratory control in the in vivo heart
1989 • 19 citations
On the Physical Properties and Potential Roles of Intracellular Water
1986 • 18 citations
In vivo correlation of myocardial metabolism, perfusion, and mechanical function during increased cardiac work
1991 • 17 citations
Activities of creatine kinase isoenzymes in single skeletal muscle fibres of trained and untrained rats
1992 • 17 citations
Effect of Creatine Kinase Activity on Mitochondrial ADP/ATP Transport
1984 • 16 citations
Whole-organ enzymology of the creatine kinase system in heart
1991 • 15 citations
Subcellular distribution of energy metabolites in the pre‐ischaemic and post‐ischaemic perfused working rat heart
1990 • 12 citations
Regelprobleme im Energiestoffwechsel des Herzmuskels
1970 • 12 citations
Recent Developments in the Study of the Conformational States and the Nucleotide Binding Sites of the ADP/ATP Carrier
1989 • 11 citations
NMR visibility of Pi in perfused rat hearts is affected by changes in substrate and contractility
1992 • 11 citations
Discussion on the state of water in the myofilament lattice and other biological systems, based on the fact that the usual concepts of colloid stability can not explain the stability of the myofilament lattice
1985 • 11 citations
Intracellular Energy Transport and Control of Cardiac Contraction
1982 • 10 citations
Importance of glycolytically produced ATP for the integrity of the threatened myocardial cell
1990 • 9 citations
Oxidative phosphorylation of creatine by respiring pig heart mitochondria in the absence of added adenine nucleotides.
1987 • 9 citations
In vivo Myocardial Bioenergetics during Acute Volume and/or Pressure Loading in a Canine Model: A <sup>31</sup>P NMR Study
1989 • 6 citations
A 31-P NMR SATURATION TRANSFER STUDY OF THE REGULATION OF CREATINE-KINASE IN THE PERFUSED RAT-HEART
1981 • 6 citations
Cellular mechanisms of alterations in myocardial contractile function in experimental cardiomyopathies.
1990 • 6 citations
Non-catalytic roles of ATP in muscle metabolism and in its control
1984 • 5 citations
Creatine kinase of heart mitochondria: no changes in its kinetic properties after inhibition of the adenine nucleotide translocator.
1983 • 4 citations
[Principles of integration of cell metabolism].
1986 • 3 citations
The Intracellular Distribution of Adenosine Triphosphate
1986 • 3 citations
Deleted Work
1955 • 0 citations