Between molecules and morphology. Extracellular matrix and creation of vascular form.

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion

1980 • 1,333 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures.

1988 • 1,209 citations

Angiogenesis in vitro

1980 • 1,041 citations

Tumor Angiogenesis

1985 • 1,038 citations

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix.

1989 • 877 citations

Fibroblast traction as a mechanism for collagen morphogenesis

1981 • 862 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

Basic fibroblast growth factor induces angiogenesis in vitro.

1986 • 828 citations

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression.

1990 • 771 citations

Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro

1989 • 746 citations

Paxillin: a new vinculin-binding protein present in focal adhesions.

1990 • 687 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Connective tissue morphogenesis by fibroblast traction

1982 • 586 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Identification of an Inhibitor of Neovascularization from Cartilage

1990 • 481 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

1990 • 452 citations

Cellular Tensegrity: Exploring How Mechanical Changes in the Cytoskeleton Regulate Cell Growth, Migration, and Tissue Pattern during Morphogenesis

1994 • 428 citations

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

1994 • 428 citations

Integrin α2β1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells

1991 • 379 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.

1989 • 363 citations

Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.

1991 • 354 citations

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis

1988 • 354 citations

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

1988 • 340 citations

Affinity of integrins for damaged extracellular matrix: αvβ3 binds to denatured collagen type I through RGD sites

1992 • 326 citations

Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

1993 • 296 citations

Tumor-related angiogenesis

1989 • 256 citations

Epidermal growth factor or transforming growth factor alpha is required for kidney tubulogenesis in matrigel cultures in serum-free medium.

1990 • 243 citations

First steps of tumor-related angiogenesis.

1991 • 241 citations

Inhibition of angiogenesis through modulation of collagen metabolism.

1988 • 240 citations

Interstitial Collagenase Is Required for Angiogenesis in Vitro

1994 • 231 citations

Reorganization of basement membrane matrices by cellular traction promotes the formation of cellular networks in vitro.

1992 • 221 citations

Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells.

1993 • 214 citations

Differentiation of canalicular cell processes in bone cells by basement membrane matrix components: Regulation by discrete domains of laminin

1990 • 198 citations

In vitro model of angiogenesis using a human endothelium‐derived permanent cell line: Contributions of induced gene expression, G‐proteins, and integrins

1992 • 198 citations

Integrin expression in human melanoma cells with differing invasive and metastatic properties

1992 • 197 citations

Regulation of in vitro capillary tube formation by anti-integrin antibodies.

1993 • 194 citations

Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor.

1990 • 183 citations

Regulation of Endothelial Cell Morphogenesis by Integrins, Mechanical Forces, and Matrix Guidance Pathways

1995 • 182 citations

TGF‐β1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors

1994 • 176 citations

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.

1994 • 152 citations

Organized type I collagen influences endothelial patterns during “spontaneous angiogenesis in vitro”: Planar cultures as models of vascular development

1995 • 146 citations

Modulation of extracellular matrix proteins by endothelial cells undergoing angiogenesis in vitro.

1991 • 134 citations

Generation of spatially periodic patterns by a mechanical instability: a mechanical alternative to the Turing model

1984 • 127 citations

Antibodies to β₁‐integrins cause alterations of aortic vasculogenesis, in vivo

1992 • 126 citations

Intussusceptive Microvascular Growth: A Common Alternative to Capillary Sprouting.

1992 • 126 citations

Phorbol esters induce angiogenesis in vitro from large‐vessel endothelial cells

1987 • 109 citations

The Effect of Fibroblasts, Vascular Smooth Muscle Cells, and Pericytes on Sprout Formation of Endothelial Cells in a Fibrin Gel Angiogenesis System

1994 • 104 citations

Stimulation of rat endothelial cell transforming growth factor-beta production by bleomycin.

1991 • 98 citations

Angiogenic growth factors in neural embryogenesis and neoplasia.

1995 • 94 citations

Structural analysis of cell: Matrix association during the morphogenesis of atrioventricular cushion tissue

1979 • 80 citations

Angiogenesis in rat aorta ring explant cultures.

1989 • 80 citations

Confocal Microscopic Analysis of Integrin Expression on the Microvasculature and its Sprouts in the Neonatal Foreskin

1994 • 75 citations

Talin: Role at sites of cell‐substratum adhesion

1990 • 74 citations

Adhesion, Shape, Proliferation, and Gene Expression of Mouse Leydig Cells are Influenced by Extracellular Matrix in Vitro1

1991 • 74 citations

Type I collagen fibrils promote rapid vascular tube formation upon contact with the apical side of cultured endothelium

1991 • 72 citations

Regulation of angiogenesis by extracellular matrix: the growth and the glue.

1994 • 71 citations

Angiogenesis-dependent tumor spread in reinforced fibrin clot culture.

1983 • 69 citations

The formation of capillary-like tubes by calf aortic endothelial cells grown in vitro

1983 • 67 citations

CAPILLARY GROWTH FROM REVERSED RAT AORTIC SEGMENTS CULTURED IN COLLAGEN GEL

1988 • 41 citations

Platelet-Derived Growth Factor-BB Stimulates Synthesis of the Integrin α2-Subunit in Human Diploid Fibroblasts

1994 • 39 citations

A comparative study on the effects of tumor necrosis factor‐α (TNF‐α), human angiogenic factor (h‐AF) and basic fibroblast growth factor (bFGF) on the chorioallantoic membrane of the chick embryo

1992 • 39 citations

Intussusceptive microvascular growth, a new mechanism of capillary network formation

1992 • 30 citations

In vitro angiogenesis in fibrin matrices containing fibronectin or hyaluronic acid

1992 • 25 citations

Combined morphological approaches in the study of network formation in tumor angiogenesis

1992 • 23 citations

Proliferative response and macromolecular synthesis by ocular cells cultured on extracellular matrix materials

1990 • 22 citations

The Effect of Three Dimensional Collagen Type I Preparation on the Structural Organization of Guinea Pig Enteric Ganglia in Culture

1993 • 10 citations