Effects of Growth Hormone Releasing Peptides on Stimulated Growth Hormone Secretion in Old Rats

Effects of Human Growth Hormone in Men over 60 Years Old

1990 • 1,560 citations

Effects of Sex and Age on the 24-Hour Profile of Growth Hormone Secretion in Man: Importance of Endogenous Estradiol Concentrations*

1987 • 927 citations

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

1981 • 829 citations

Impaired growth hormone secretion in the adult population: relation to age and adiposity.

1981 • 643 citations

Age-Related Change in the Twenty-Four Hour Spontaneous Secretion of Growth Hormone

1972 • 640 citations

Pathological Changes During Aging in, Barrier-Reared Fischer 344 Male Rats

1977 • 526 citations

Dopamine Agonists and Pituitary Tumor Shrinkage

1992 • 441 citations

Effects of Short Term Administration of Recombinant Human Growth Hormone to Elderly People*

1990 • 375 citations

Growth Hormone (GH)-Releasing Peptide Stimulates GH Release in Normal Men and Acts Synergistically with GH-Releasing Hormone*

1990 • 315 citations

On the Actions of the Growth Hormone-Releasing Hexapeptide, GHRP*

1991 • 308 citations

The Synergistic Effects of His-D-Trp-Ala-Trp-D-Phe- Lys-NH₂on Growth Hormone (GH)-Releasing Factor- Stimulated GH Release and Intracellular Adenosine 3',5'-Monophosphate Accumulation in Rat Primary Pituitary Cell Culture

1989 • 298 citations

GH3 pituitary adenoma cells can reverse thymic aging in rats.

1986 • 282 citations

Decreased Pulsatile Release of Growth Hormone in Old Male Rats*

1980 • 272 citations

Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors.

1992 • 238 citations

AGE-RELATED CHANGES IN PLASMA GROWTH HORMONE RESPONSE TO GROWTH HORMONE-RELEASING FACTOR IN MAN

1984 • 232 citations

Mammosomatotropes: Presence and Functions in Normal and Neoplastic Pituitary Tissue*

1991 • 214 citations

Immunologic deficiencies in senescence. I. Characterization of intrinsic deficiencies.

1972 • 177 citations

An analytical review

1984 • 177 citations

Hormones and immunological capacity. II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone and thyroxin.

1969 • 149 citations

Lymphocytes, Hormones and Ageing

1972 • 149 citations

Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites

1989 • 148 citations

The Effect of Recombinant Human Growth Hormone on Malnourished Older Individuals

1991 • 146 citations

Desensitization studies using perifused rat pituitary cells show that growth hormone-releasing hormone and His-d-Trp-Ala-Trp-d-Phe-Lys-NH2 stimulate growth hormone release through distinct receptor sites

1991 • 146 citations

Evidence for a Role of Protein Kinase-C in His-D-Trp Ala-Trp-D-Phe-Lys-NH₂-Induced Growth Hormone Release from Rat Primary Pituitary Cells

1991 • 136 citations

Effects of Sex and Age on Growth Hormone Response to Growth Hormone-Releasing Hormone in Healthy Individuals

1987 • 130 citations

Responses of Growth Hormone (GH) and Somatomedin-C to GH-Releasing Hormone in Healthy Aging Men*

1986 • 130 citations

Interferon‐γ‐induced priming for secretion of superoxide anion and tumor necrosis factor‐α declines in macrophages from aged rats

1990 • 121 citations

Role of growth hormone in regulating T‐Dependent immune events in aged, nude, and transgenic rodents

1987 • 117 citations

Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)- releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors

1992 • 105 citations

Immunoreactive Somatostatin in Rat Hypophyseal Portal Blood: Effects of Anesthetics*

1979 • 103 citations

Reduced growth hormone releasing factor (GHRF)-like immunoreactivity and GHRF gene expression in the hypothalamus of aged rats

1989 • 96 citations

Repetitive Growth Hormone-Releasing Hormone Administration Restores the Attenuated Growth Hormone (GH) Response to GH-Releasing Hormone Testing in Normal Aging

1989 • 88 citations

Diminished Pituitary Responsiveness to Growth Hormone-Releasing Factor in Aging Male Rats*

1986 • 84 citations

Low somatomedin-C levels in older men rise in response to growth hormone administration.

1981 • 84 citations

Effects of CNS Active Drugs and Somatostatin Antiserum on Growth Hormone Release in Young and Old Male Rats

1981 • 84 citations

IMPAIRED ABILITY OF OLD MALE RATS TO SECRETE GROWTH HORMONEIN VIVOBUT NOTIN VITROIN RESPONSE TO hpGRF(1–44)

1983 • 84 citations

Growth Hormone Secretory Patterns in Young, Middle-Aged and Old Female Rats

1987 • 80 citations

Age-Related Changes in Growth Hormone Releasing Factor and Somatostatin in the Rat Hypothalamus

1988 • 78 citations

ALTERATIONS OF PITUITARY GROWTH HORMONE-RELEASING FACTOR BINDING SITES IN AGING RATS

1991 • 62 citations

Pituitary epithelial cell implants reverse the accumulation of CD4-CD8- lymphocytes in thymus glands of aged rats.

1992 • 52 citations

Relationship between growth hormone-releasing hormone and somatostatin in the rat: effects of age and sex on content and in-vitro release from hypothalamic explants

1989 • 52 citations

Immunologic Deficiencies in Senescence

1972 • 49 citations

Pyridostigmine partially restores the GH responsiveness to GHRH in normal aging

1990 • 48 citations

The Immune System and the Aging Process in Man

1980 • 44 citations

Role of selected endogenous peptides in growth hormone-releasing hexapeptide activity: analysis of growth hormone-releasing hormone, thyroid hormone-releasing hormone, and gonadotropin-releasing hormone.

1992 • 41 citations

Adrenotropic activity of mammo-somatotropic tumors in rats and mice. I. Biologic aspects.

1962 • 41 citations

Robust Growth Hormone (GH) secretion in aged female rats co-administered GH-releasing hexapeptide (GHRP-6) and GH-releasing hormone (GHRH)

1991 • 38 citations

GROWTH HORMONE CONTENT AND METABOLIC ACTIONS OF HUMAN PITUITARY GLANDS1,2

1957 • 38 citations

The Absence of an Age-Related Change in the Pituitary Response to Growth Hormone-Releasing Factor in Rats

1983 • 38 citations

Evidence for a Defect in Growth Hormone-Releasing Factor Signal Transduction in the Dwarf (dw/dw) Rat Pituitary*

1991 • 38 citations

Characterization of [125I-Tyr10]human growth hormone-releasing factor(1–44) amide binding to rat pituitary: evidence for high and low affinity classes of sites

1990 • 37 citations

Growth Hormone Releasing Hormone Induced Release of Growth Hormone in Aging Male Rats: Dependence on Pharmacological Manipulation and Endogenous Somatostatin Release

1988 • 37 citations

Effect of age on T cell differentiation.

1978 • 35 citations

Sex Differences in Growth Hormone (GH) Secretion by Rats Administered GH-Releasing Hexapeptide

1991 • 35 citations

Pituitary epithelial cell implants reverse the accumulation of CD4-CD8- lymphocytes in thymus glands of aged rats

1992 • 29 citations

Different Regulation of Growth Hormone-Releasing Factor-Sensitive Adenylate Cyclase in the Anterior Pituitary of Young and Aged Rats*

1987 • 26 citations

Growth Hormone-Releasing Hormone and Growth Hormone-Releasing Peptide as Potential Therapeutic Modalities

1990 • 25 citations

Plasma levels of growth hormone correlate with the severity of pathologic changes in the renal structure of aging rats.

1991 • 24 citations

Immunological aspects of aging: Early changes in thymic activity

1984 • 23 citations

Impact of age-related changes in serotonin and norepinephrine metabolism on reproductive function in female rats: An analytical review

1984 • 22 citations

Role of selected endogenous peptides in growth hormone-releasing hexapeptide activity: analysis of growth hormone-releasing hormone, thyroid hormone-releasing hormone, and gonadotropin-releasing hormone

1992 • 21 citations

Systems analysis of possible mechanisms of mammalian aging

1977 • 21 citations

Effects of Human Growth Hormone in Elderly Males

1969 • 20 citations

Regulation of neuroendocrine aging

1989 • 16 citations

Regulation of neuroendocrine aging

1988 • 15 citations

The Influence of Age on Human Pancreatic Growth Hormone Releasing Hormone Stimulated Growth Hormone Secretion

1988 • 15 citations

Decline in Growth Hormone Secretion in Aging Animals and Man

2015 • 14 citations

Adrenotropic activity of mammo-somatotropic tumors in rats and mice. II. Tumor hormonal content and host adrenal function.

1963 • 11 citations

EFFECT OF PITUITARY GROWTH HORMONE ON LYMPHATIC TISSUES, THORACIC DUCT LYMPH FLOW, LYMPH PROTEIN AND LYMPHOCYTE OUTPUT IN THE RAT¹

1959 • 11 citations

Age-related differences in the growth hormone secretory response to hGHRH 1-44 in male rats from infancy through puberty

1987 • 8 citations

Aging enhances inhibitory action of somatostatin in rat pancreas

1992 • 7 citations

Remembrance: neuroendocrinology and aging. A perspective.

1992 • 4 citations

Aging enhances inhibitory action of somatostatin in rat pancreas.

1992 • 4 citations

Remembrance: neuroendocrinology and aging. A perspective

1992 • 4 citations