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Zinc Finger Transcription Factors as Molecular Targets for Nitric Oxide-mediated Immunosuppression: Inhibition of IL-2 Gene Expression in Murine Lymphocytes

Data up to Jan 2025

Published1999
Citations75
References39

Total Citations Per Year

Abstract

References (39)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

1998 • 1,566 citations

Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

1995 • 707 citations

Inducible nitric oxide synthase in human diseases

1998 • 586 citations

Protein motifs 5. Zinc fingers.

1995 • 544 citations

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

1998 • 510 citations

Zinc fingers

1995 • 501 citations

Inhibition of NF- B DNA Binding by Nitric Oxide

1996 • 479 citations

Molecular basis of "suppressor" macrophages. Arginine metabolism via the nitric oxide synthetase pathway.

1991 • 344 citations

Nitric oxide: a pathogenetic factor in autoimmunity

1992 • 342 citations

Nitric Oxide Destroys Zinc-Sulfur Clusters Inducing Zinc Release from Metallothionein and Inhibition of the Zinc Finger-Type Yeast Transcription Activator LAC9

1994 • 276 citations

Nitric oxide in autoimmune disease: cytotoxic or regulatory mediator?

1998 • 262 citations

Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine.

1990 • 230 citations

The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation

1995 • 229 citations

Unique structure of murine interleukin-2 as deduced from cloned cDNAs

1985 • 205 citations

Review

1995 • 186 citations

The Multiplex Function of Nitric Oxide in (Auto)immunity

1998 • 175 citations

Immunosuppression induced by nitric oxide and its inhibition by interleukin‐4

1992 • 172 citations

Nitric oxide mediates intracytoplasmic and intranuclear zinc release

1997 • 163 citations

The DNA‐Binding Efficiency of Sp1 is Affected by Redox Changes

1994 • 156 citations

A Regulatory Element in the Human Interleukin 2 Gene Promoter Is a Binding Site for the Zinc Finger Proteins Sp1 and EGR-1

1995 • 150 citations

Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection

1992 • 136 citations

Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells.

1986 • 133 citations

Nitric oxide inhibits the secretion of T‐helper 1‐ and T‐helper 2‐associated cytokines in activated human T cells‘pa

1997 • 126 citations

Inactivation of zinc finger transcription factors provides a mechanism for a gene regulatory role of nitric oxide

2000 • 118 citations

Modulation of AP‐1 activity by nitric oxide (NO) in vitro: NO‐mediated modulation of AP‐1

1994 • 109 citations

Nitric oxide increased interleukin‐4 expression in T lymphocytes

1997 • 91 citations

The Early Growth Response Protein (EGR-1) Regulates Interleukin-2 Transcription by Synergistic Interaction with the Nuclear Factor of Activated T Cells

1998 • 83 citations

Nitric Oxide Inhibits the Proliferation of T-Helper 1 and 2 Lymphocytes without Reduction in Cytokine Secretion

1999 • 66 citations

Role of Zinc-Coordination and of the Glutathione Redox Couple in the Redox Susceptibility of Human Transcription Factor Sp1

1994 • 63 citations

Inhibition of IL‐2 production by nitric oxide: A novel self‐regulatory mechanism for Th1 cell proliferation

1997 • 45 citations

[25] Detection of nitric oxide interaction with zinc finger proteins

1996 • 40 citations

Is there a role for nitric oxide in regulation of T cell secretion of IL-2?

1996 • 22 citations

Effects of hydrogen peroxide, nitric oxide and antioxidants on NF-κB

1996 • 13 citations

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Zinc Finger Transcription Factors as Molecular Targets for Nitric Oxide-mediated… (1999) – Molecular Medicine | Metascience Observatory Explorer