Co-inheritance of the 20210A Allele of the Prothrombin Gene Increases the Risk of Thrombosis in Subjects with Familial Thrombophilia

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

1996 • 3,124 citations

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

1993 • 1,997 citations

Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis

1995 • 1,117 citations

Increased fetal loss in women with heritable thrombophilia

1996 • 654 citations

Inherited Thrombophilia: Part 1

1996 • 600 citations

Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families

1994 • 446 citations

Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect

1993 • 354 citations

Resistance to activated protein C as an additional genetic risk factor in hereditary deficiency of protein S

1995 • 314 citations

Inherited predisposition to thrombosis

1993 • 166 citations

High prevalence of a mutation in the factor V gene within the U.K. population: relationship to activated protein C resistance and familial thrombosis

1994 • 148 citations

The simultaneous measurement of total and free protein S by ELISA

1988 • 48 citations