Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

1989 • 1,059 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Mutation of Antitrypsin to Antithrombin

1983 • 430 citations

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

1988 • 405 citations

Protein S and C4b-Binding Protein: Components Involved in the Regulation of the Protein C Anticoagulant System

1991 • 357 citations

Inhibition of protein Ca cofactor function of human and bovine protein S by C4b-binding protein.

1986 • 296 citations

Family studies and prenatal diagnosis in severe von Willebrand disease by polymerase chain reaction amplification of a variable number tandem repeat region of the von Willebrand factor gene

1990 • 160 citations

The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain.

1991 • 120 citations

Thromboembolic Disease – Critical Evaluation of Laboratory Investigation

1992 • 119 citations

Characterization of functionally important domains in human vitamin K-dependent protein S using monoclonal antibodies.

1990 • 112 citations

Protein C Inhibitor: Structure and Function

1989 • 76 citations

A Fatal Thrombotic Disorder Associated with an Acquired Inhibitor of Protein C

1987 • 68 citations

Identification of a new protein involved in the regulation of the anticoagulant activity of activated protein C. Protein S-binding protein.

1986 • 34 citations

Inhibition of platelet prothrombinase activity by a lupus anticoagulant

1983 • 33 citations

An HphI‐polymorphism in exon 28 of the von Willebrand factor gene, and its frequency among patients with various forms of von Willebrand's disease

1991 • 16 citations