Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments.

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

1993 • 1,186 citations

Poly(ethylenimine) and its role in gene delivery

1999 • 1,182 citations

Mechanism of DNA Release from Cationic Liposome/DNA Complexes Used in Cell Transfection^,

1996 • 1,103 citations

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

1999 • 819 citations

In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers

1996 • 805 citations

Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells

1998 • 711 citations

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.

1992 • 657 citations

Polyethylenimine-mediated gene delivery: a mechanistic study

2001 • 509 citations

Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes

1999 • 494 citations

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini

2001 • 481 citations

Structure−Activity Relationships of Water-Soluble Cationic Methacrylate/Methacrylamide Polymers for Nonviral Gene Delivery

1999 • 402 citations

Characterization of Vectors for Gene Therapy Formed by Self-Assembly of DNA with Synthetic Block Co-Polymers

1996 • 365 citations

Poly(ethylenimine)-mediated transfection: A new paradigm for gene delivery

2000 • 318 citations

Protein determination using bicinchoninic acid in the presence of sulfhydryl reagents

1988 • 311 citations

Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human Fibroblasts

1997 • 282 citations

Design of imidazole-containing endosomolytic biopolymers for gene delivery

2000 • 264 citations

Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes

1996 • 253 citations

Polyelectrolyte Vectors for Gene Delivery: Influence of Cationic Polymer on Biophysical Properties of Complexes Formed with DNA

1999 • 249 citations

Getting across the nuclear pore complex

1999 • 197 citations

High-Generation Polycationic Dendrimers Are Unusually Effective at Disrupting Anionic Vesicles: Membrane Bending Model

2000 • 196 citations

Effects of Polyethyleneimine on Endocytosis and Lysosome Stability

1998 • 150 citations

Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides

2000 • 63 citations

Uptake and Intracellular Fate of Polyethylenimine in Vivo

2000 • 52 citations

Delivery of an anti-HIV-1 ribozyme into HIV-infected cells via cationic liposomes

1998 • 35 citations

Reversal of HER-2 over-expression renders human ovarian cancer cells highly resistant to taxol

2000 • 32 citations

Reversal of multidrug resistance by a liposome- MDR 1 ribozyme complex

1998 • 22 citations

Lipospermine-mediated gene transfer technique into murine cultured cortical cells

1997 • 10 citations