Reversal of multidrug resistance by a liposome- MDR 1 ribozyme complex

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Simple RNA enzymes with new and highly specific endoribonuclease activities

1988 • 1,118 citations

Cationic liposome-mediated transfection

1989 • 974 citations

Rosette-Forming Human Lymphoid Cell Lines. I. Establishment and Evidence for Origin of Thymus-Derived Lymphocytes<xref ref-type="fn" rid="FN1">2</xref>

1972 • 916 citations

Multiple-Drug Resistance in Human Cancer

1987 • 703 citations

Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats.

1986 • 301 citations

Genetics of multidrug resistance.

1988 • 118 citations

Ribozymes and Their Medical Implications

1988 • 113 citations

Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme.

1994 • 112 citations

Reversion of multidrug resistance in the P-glycoprotein-positive human pancreatic cell line (EPP85-181RDB) by introduction of a hammerhead ribozyme

1994 • 86 citations

Inhibition of gene expression with ribozymes

1994 • 79 citations

Increased mdr gene expression and decreased drug accumulation in multidrug-resistant human melanoma cells.

1988 • 75 citations

Fusion between large phagocytic vesicles: Targeting of yeast and other particulates to phagolysosomes that shelter the bacterium Coxiella burnetii or the protozoan Leishmania amazonensis in chinese hamster ovary cells

1994 • 69 citations

Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells

1997 • 63 citations

P-glycoprotein expression in human breast cancer cells.

1987 • 55 citations

Increase of lipid fluidity and suppression of proliferation resulting from liposome uptake by human keratinocytes in vitro

1991 • 22 citations

Endosomolytic Activity of Cationic Liposomes Enhances the Delivery of Human Immunodeficiency Virus-1 Trans-activator Protein (TAT) to Mammalian Cells

1995 • 21 citations

Expression of dihydrofolate reductase and multidrug resistance genes in trimetrexate-resistant human leukemia cell lines

1993 • 15 citations

Effects of colchicine and cytochalasin B on distribution of concanavalin A receptors in isolated and cultured guinea pig epidermal cells

1987 • 9 citations