Molecular Basis of Tumor Progression: Mechanisms of Organ‐Specific Tumor Metastasis

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

1889 • 4,920 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding

1987 • 677 citations

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

1987 • 591 citations

Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites

1988 • 508 citations

Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites

1988 • 405 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Cancer Cell Invasion and Metastasis

1992 • 260 citations

Oligosaccharide modification by swainsonine treatment inhibits pulmonary colonization by B16-F10 murine melanoma cells.

1986 • 184 citations

Insulin and Insulin‐like Growth Factor 1 Stimulate Proliferation of Metastatic Variants of Colon Carcinoma 26

1989 • 181 citations

Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion.

1989 • 158 citations

Metastatic tumor cell interactions with endothelium, basement membrane and tissue

1989 • 157 citations

Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors

1987 • 145 citations

Organ specificity of metastatic tumor colonization is related to organ‐selective growth properties of malignant cells

1986 • 145 citations

Migration of tumor cells to organ-derived chemoattractants.

1985 • 135 citations

Mast cells and matrix degradation at sites of tumour invasion in rat mammary adenocarcinoma

1986 • 121 citations

Growth-Regulatory Factors for Normal, Premalignant, and Malignant Human Cells In Vitro

1990 • 117 citations

Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis

1992 • 114 citations

An animal model for colon cancer metastasis: establishment and characterization of murine cell lines with enhanced liver-metastasizing ability.

1987 • 106 citations

Implications of endogenous tumor cell surface lectins as mediators of cellular interactions and lung colonization.

1986 • 105 citations

Microvascular endothelial cell heterogeneity: Interactions with leukocytes and tumor cells

1990 • 104 citations

Expression of tumor antigen correlated with metastatic potential of Lewis lung carcinoma and B16 melanoma clones in mice.

1986 • 95 citations

Heparan sulfate and heparin as a potentiator or a suppressor of growth of normal and transformed vascular endothelial cells

1987 • 89 citations

Carcinoembryonic antigen: Function in metastasis by human colorectal carcinoma

1989 • 89 citations

Leukocyte Interactions Mediated by Selectins

1991 • 88 citations

Random and nonrandom processes in metastasis, and metastatic inefficiency.

1983 • 84 citations

Tumor and host molecules important in the organ preference of metastasis.

1991 • 74 citations

Purification and some properties of a lung-derived growth factor that differentially stimulates the growth of tumor cells metastatic to the lung.

1989 • 73 citations

Adhesive, invasive, and growth properties of selected metastatic variants of a murine large-cell lymphoma.

1989 • 61 citations

Correlation of Inhibition of Adhesion of Large Cell Lymphoma and Hepatic Sinusoidal Endothelial Cells by RGD-Containing Peptide Polymers with Metastatic Potential: Role of Integrin-Dependent and -Independent Adhesion Mechanisms

1989 • 53 citations

C‐CAM (cell‐CAM 105) – a member of the growing immunoglobulin superfamily of cell adhesion proteins

1991 • 52 citations

Differential growth properties of metastatic large-cell lymphoma cells in target organ-conditioned medium

1987 • 46 citations

Lung‐derived growth factor that stimulates the growth of lung‐metastasizing tumor cells: Identification as transferrin

1991 • 41 citations

Coincidental Acquisition of Growth Autonomy and Metastatic Potential During the Malignant Transformation of Factor-Dependent CCL39 Lung Fibroblasts

1988 • 39 citations

Growth stimulating activity of lung extract on lung-colonizing colon 26 clones and its partial characterization

1988 • 37 citations

Organ-specific chemotactic factors present in lung extracellular matrix

1989 • 28 citations

Detection of the plasmin system in human mammary pathology using immunofluorescence.

1986 • 23 citations

Macrophage and lymphocyte potentiation of syngeneic tumor cell and host fibroblast collagenolytic activity in rats.

1988 • 21 citations

Purification and characterization of a Mr ∼66,000 lung-derived (paracrine) growth factor that preferentially stimulates the in vitro proliferation of lung-metastasizing tumor cells

1990 • 21 citations

Affinity-purified site-directed antibody recognizes the entire annexin protein family

1989 • 15 citations

Effects of glycosaminoglycans and extracellular matrix components on metastatic rat rhabdomyosarcoma tumor and myoblast cell proliferation

1990 • 14 citations

Tumor cell-surface galactose correlates with the degree of colorectal liver metastasis

1989 • 14 citations