Growth-Regulatory Factors for Normal, Premalignant, and Malignant Human Cells In Vitro

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma

1984 • 963 citations

Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.

1982 • 552 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma

1981 • 492 citations

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

1988 • 489 citations

Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen

1987 • 485 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

Clonal growth of normal human epidermal keratinocytes in a defined medium

1982 • 442 citations

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract.

1984 • 435 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells.

1986 • 310 citations

Clonal growth of normal adult human bronchial epithelial cells in a serum-free medium

1982 • 278 citations

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1984 • 277 citations

The biologic forms of malignant melanoma

1986 • 272 citations

Selective stimulation of small cell lung cancer clonal growth by bombesin and gastrin-releasing peptide

1987 • 269 citations

Characteristics of cultured human melanocytes isolated from different stages of tumor progression.

1985 • 264 citations

Cultivation, frozen storage, and clonal growth of normal human epidermal keratinocytes in serum-free media

1985 • 259 citations

bFGF is the putative natural growth factor for human melanocytes

1987 • 259 citations

Biology of tumor progression in human melanocytes.

1987 • 236 citations

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents.

1984 • 233 citations

Production of transforming growth factors by human colon cancer lines.

1986 • 227 citations

New Techniques for the In Vitro Culture of Human Skin Keratinocytes and Perspectives on Their Use for Grafting of Patients With Extensive Burns

1986 • 223 citations

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

1987 • 222 citations

Cytogenetics of human malignant melanoma and premalignant lesions

1984 • 213 citations

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.

1986 • 193 citations

Growth factors produced by sarcoma virus-transformed cells.

1978 • 191 citations

Anti-idiotype immunization of cancer patients: modulation of the immune response.

1987 • 190 citations

Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma

1985 • 190 citations

Selective Cultivation of Human Melanocytes from Newborn and Adult Epidermis

1984 • 189 citations

Karyotypic evolution in human malignant melanoma

1986 • 189 citations

Chemical and biological properties of a growth factor from human‐cultured osteosarcoma cells: Resemblance with platelet‐derived growth factor

1980 • 188 citations

Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.

1986 • 187 citations

Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors.

1984 • 163 citations

Binding of an antagonistic monoclonal antibody to an intact and fragmented EGF-receptor polypeptide

1987 • 161 citations

A glioma-derived analog to platelet-derived growth factor: demonstration of receptor competing activity and immunological crossreactivity.

1984 • 160 citations

Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.

1987 • 153 citations

Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors

1987 • 145 citations

Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.

1985 • 141 citations

Biological effect of epidermal growth factor on the in vitro growth of human tumors.

1987 • 134 citations

Anti-Idiotypic Antibodies Bear the Internal Image of a Human Tumor Antigen

1986 • 126 citations

A simplified method for passage and long-term growth of human mammary epithelial cells

1986 • 123 citations

Production of PDGF‐like growth factor by breast cancer cell lines

1985 • 120 citations

Control of growth and differentiation in vitro of human keratinocytes cultured in serum-free medium

1987 • 119 citations

Melanoma Antigens: Immunological and Biological Characterization and Clinical Significance

1988 • 116 citations

Synthesis of a PDGF-like growth factor in human glioma and sarcoma cells suggests the expression of the cellular homologue to the transforming protein of simian sarcoma virus

1983 • 116 citations

Phenotypic diversity in cultured cerebral microvascular endothelial cells

1988 • 114 citations

Calcium regulation of normal human mammary epithelial cell growth in culture

1984 • 113 citations

Regulatory factors that determine growth and phenotype of normal human melanocytes*1

1988 • 98 citations

Genetic evidence for progressive selection and overgrowth of primary tumors by metastatic cell subpopulations.

1988 • 97 citations

The stimulation of normal human melanocyte proliferation in vitro by melanocyte growth factor from bovine brain

1985 • 94 citations

Growth and characterization of normal human urothelium in vitro

1983 • 94 citations

Clonal variation in the production of a platelet-derived growth factor-like protein and expression of corresponding receptors in a human malignant glioma.

1986 • 89 citations

Growth kinetics and differentiation in vitro of normal human uroepithelial cells on collagen gel substrates in defined medium

1987 • 88 citations

A synthetic fragment of rat transforming growth factor α with receptor binding and antigenic properties

1985 • 86 citations

Expression of melanoma-associated antigens in rapidly dividing human melanocytes in culture.

1987 • 83 citations

Primary culture of human oral epithelial cells. Growth requirements and expression of differentiated characteristics.

1987 • 81 citations

Expression of multiple growth factors in a human lung cancer cell line

1987 • 63 citations

Comparative endocrinology-paracrinology-autocrinology of human adult large vessel endothelial and smooth muscle cells

1988 • 60 citations

Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines.

1988 • 59 citations

Growth and Phenotoypic Characteristics of Human Nevus Cells in Culture

1988 • 56 citations

The Growth and Structure of Human Oral Keratinocytes in Culture

1987 • 53 citations

Growth of normal and neoplastic urothelium and response to epidermal growth factor in a defined serum-free medium.

1987 • 53 citations

Normal and transformed human prokeratinocytes express divergent effects of a tumor promoter on cell cycle-mediated control of proliferation and differentiation

1985 • 53 citations

Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells.

1987 • 51 citations

Induction of specific immunity to human colon carcinoma by anti‐idiotypic antibodies to monoclonal antibody CO17‐1A

1987 • 51 citations

Phenotypic characteristics of cells derived from precursors of human melanoma.

1983 • 42 citations

Human breast epithelial cells in serum‐free collagen gel primary culture: Growth, morphological, and immunocytochemical analysis

1987 • 41 citations

Coincidental Acquisition of Growth Autonomy and Metastatic Potential During the Malignant Transformation of Factor-Dependent CCL39 Lung Fibroblasts

1988 • 39 citations

Human colon cancer cell lines secrete α TGF-like activity

1987 • 33 citations

The effect of substrate and epidermal growth factor on human placental trophoblast cells in culture

1986 • 29 citations

Interactions between growth factor receptors and corresponding monoclonal antibodies in human tumors

1987 • 21 citations

Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells

1988 • 16 citations

Human microvascular endothelial cells: Coordinate induction of morphologic differentiation and twofold extension of life span

1988 • 11 citations

Growth-promoting effect of 12-O-tetradecanoylphorbol-13-acetate on cultured normal human fetal kidney epithelial cells.

1986 • 5 citations

New Directions for Space Astronomy

1987 • 4 citations