Alcohol-induced pancreatic injury (Part 2) evolution of pathogenetic theories

Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue

1977 • 571 citations

Effects of ethanol on lipid metabolism.

1979 • 374 citations

SYNTHESIS, INTRACELLULAR TRANSPORT AND DISCHARGE OF EXPORTABLE PROTEINS IN THE PANCREATIC ACINAR CELL AND OTHER CELLS

1978 • 279 citations

Chronic relapsing pancreatitis. A study of twenty-nine cases without associated disease of the biliary or gastro-intestinal tract.

1968 • 212 citations

Chronic Calcifying Pancreatitis—Chronic Alcoholic Pancreatitis

1974 • 209 citations

Effects of ethanol on liver microtubules and Golgi apparatus. Possible role in altered hepatic secretion of plasma proteins.

1979 • 164 citations

Characterization of a protein isolated from pancreatic calculi of men suffering from chronic calcifying pancreatitis

1979 • 154 citations

Three-Dimensional Reconstruction of the Pancreatic Ducts in Chronic Pancreatitis

1972 • 153 citations

A fresh approach to the pathogenesis of pancreatitis.

1968 • 137 citations

Pancreatic stone protein, a phosphoprotein which inhibits calcium carbonate precipitation from human pancreatic juice

1983 • 137 citations

A comparison of alcoholic pancreatitis in rat and man

1971 • 132 citations

Association of lactoferrin with other proteins, as demonstrated by changes in electrophoretic mobility

1971 • 119 citations

Alcohol and Amino Acid Transport in the Human Small Intestine

1969 • 119 citations

Pancreatic stone protein. II. Implication in stone formation during the course of chronic calcifying pancreatitis

1985 • 116 citations

Pancreatic Function and Intestinal Absorption in Chronic Alcoholism

1970 • 115 citations

Stimulation of Pancreatic Secretion by Extracts of the Pyloric Gland Area of the Stomach

1965 • 114 citations

The clinical picture of the sequential development of acute hemorrhagic pancreatitis in the dog.

1957 • 109 citations

Gradations of pancreatitis, edematous, through hemorrhagic, experimentally produced by controlled injection of microspheres into blood vessels in dogs.

1962 • 104 citations

Motor function of the opossum sphincter of Oddi.

1983 • 98 citations

Pancreatic Acinar Cell Function and Morphology in Rats Chronically Fed an Ethanol Diet

1982 • 92 citations

Pancreatic Calcification

1958 • 87 citations

Modifications of pure human pancreatic juice induced by chronic alcohol consumption

1979 • 86 citations

Ultrastructure of the Rat Exocrine Pancreas After Long Term Intake of Ethanol

1970 • 85 citations

Effects of chronic alcohol abuse on exocrine pancreatic secretion in man

1985 • 85 citations

Endogenous Cathepsin Activation of Trypsinogen in Extracts of Dog Pancreas.

1961 • 84 citations

Effects of ethyl alcohol on sphincteric resistance at the choledocho-duodenal junction in man.

1968 • 76 citations

Studies of Pure Pancreatic Secretions in Chronic Alcoholic Subjects without Pancreatic Insufficiency

1980 • 76 citations

Experimental Pancreatitis

1962 • 76 citations

The molecular characteristics of a human pancreatic acidic phosphoprotein that inhibits calcium carbonate crystal growth

1984 • 74 citations

Newer concept for the pathogenesis of chronic alcoholic pancreatitis.

1977 • 69 citations

Venous Stasis in the Transition of Edematous Pancreatitis to Necrosis

1963 • 68 citations

Alcohol as a Gastric Secretory Stimulant

1957 • 67 citations

Direct demonstration of the formation of prostaglandin E2 due to phosphatidylinositol breakdown associated with stimulation of enzyme secretion in the pancreas.

1981 • 65 citations

Route of Retrograde Flow in the Exocrine Pancreas During Ductal Hypertension

1971 • 60 citations

Etiology of acute pancreatitis

1942 • 60 citations

Alcohol Causes a Fatty Pancreas. A Rat Model of Ethanol‐Induced Pancreatic Steatosis

1982 • 60 citations

Evidence for a role in stimulus--secretion coupling of prostaglandins derived from release of arachidonoyl residues as a result of phosphatidylinositol breakdown.

1980 • 59 citations

Lysosomal enzymes in pure pancreatic juice from normal healthy volunteers and chronic alcoholics

1979 • 58 citations

Protective effects of PGE2 on diet-induced acute pancreatitis in mice

1980 • 58 citations

Etiology of acute pancreatitis; an experimental study.

1948 • 58 citations

Alcohol and the pancreas. I. Clinical associations and histopathology of minimal pancreatic inflammation.

1981 • 58 citations

Chronic pancreatitis and lithiasis; a clinicopathologic study of 62 cases of chronic pancreatitis.

1949 • 56 citations

Effects of Chronic Intragastric Ethanol Administration on Canine Exocrine Pancreatic Secretion

1973 • 55 citations

Continuous Perfusion of Bile and Protease Activators Through the Pancreas

1963 • 54 citations

Proteolysis of human trypsinogen 1. Pathogenic implication in chronic pancreatitis

1984 • 50 citations

Ductal and Vascular Factors in Etiology of Experimentally Induced Acute Pancreatitis

1957 • 50 citations

Ethanol metabolism by the rat pancreas

1981 • 49 citations

Pancreatic stone protein. I. Evidence that it is encoded by a pancreatic messenger ribonucleic acid

1985 • 47 citations

Bacterial regurgitation in experimental pancreatitis

1964 • 47 citations

Effects of Intravenous Alcohol on Motility of the Duodenum and of the Sphincter of Oddi

1970 • 47 citations

Effects of ethanol on the sphincter of Oddi: an endoscopic manometric study.

1983 • 46 citations

Inhibitory Effect of Ethanol on Canine Exocrine Pancreatk Secretion

1972 • 46 citations

Correlation of the histologic observations and operative findings in patients with chronic pancreatitis.

1971 • 45 citations

RADIOIMMUNOASSAY OF LACTOFERRIN IN PANCREATIC JUICE AS A TEST FOR PANCREATIC DISEASES

1978 • 45 citations

Lactoferrin and albumin in human pancreatic juice

1980 • 45 citations

Effect of Prolonged Alcohol Consumption in Rats on Pancreatic Protein Synthesis ,

1968 • 44 citations

Chronic Alcoholism and Canine Exocrine Pancreas Secretion

1977 • 44 citations

Chronic duodenal obstruction: A mechano-vascular etiology of pancreatitis

1960 • 44 citations

Comparaison des proteines de sucs pancreatiques humains normaux et pathologiques. Dosage des proteines seriques et mise en evidence d'une proteine particuliere dans la pancreatite chronique calcifiante

1971 • 42 citations

Experimental studies concerning factors in the pathogenesis of acute pancreatitis.

1954 • 41 citations

POST-GASTRECTOMY PROXIMAL JEJUNAL LOOP OBSTRUCTION SIMULATING ACUTE PANCREATITIS

1954 • 41 citations

Effect of chronic ethanol feeding on pancreatic enzyme secretion in ratsin Vitro

1983 • 40 citations

Combined effects of protein deficiency and chronic ethanol consumption on rat pancreas

1988 • 40 citations

Disease of the Pancreas. Its Cause and Nature.

1903 • 40 citations

Effects of Chronic Ethanol Administration on Canine Exocrine Pancreatic Secretion

1974 • 39 citations

Chronic duodenal obstruction: A mechano-vascular etiology of pancreatitis

1960 • 39 citations

The role of incomplete pancreatic duct obstruction in the etiology of pancreatitis.

1960 • 39 citations

Increased interdigestive pancreatic trypsin secretion in alcoholic pancreatic disease

1985 • 38 citations

Fine structure of early experimental acute pancreatitis in dogs.

1973 • 38 citations

THE EFFECTS OF ETHYL ALCOHOL ON PANCREATIC EXOCRINE FUNCTION

1966 • 37 citations

Reflux of duodenal contents in the pathogenesis of pancreatitis

1964 • 37 citations

Ethanol Ingestion and Incorporation of 32P into Phospholipids of Pancreas in the Rat

1969 • 37 citations

An Alternate Mechanism for the Formation of Protein Plugs in Chronic Calcifying Pancreatitis

1974 • 36 citations

ACUTE PANCREATITIS (PANCREATIC NECROSIS)

1931 • 36 citations

Studies on Pancreatic Stones

1981 • 34 citations

Effect of ethanol on cholecystokinin-induced enzyme secretion from isolated rat pancreatic acini

1984 • 33 citations

The incidence and diagnosis of pancreatic lithiasis

1941 • 33 citations

Effect of Chronic Ethanol Administration on Enzyme and Lipid Properties of Liver Plasma Membranes in Long and Short Sleep Mice

1985 • 32 citations

Characterization of an additional protein in pancreatic juice of men with chronic calcifying pancreatitis Identification to lactoferrin

1974 • 32 citations

Regurgitation in Experimental Pancreatitis

1964 • 31 citations

Effect of pressure on the integrity of the duct-acinar system of the pancreas

1970 • 30 citations

Duodenal reflux and the etiology of pancreatitis.

1967 • 29 citations

Atropine and exocrine pancreatic secretion in alcohol-fed dogs.

1975 • 28 citations

Chronic relapsing pancreatitis.

1951 • 28 citations

Acute pancreatitis complicating choledochal sphincterotomy

1954 • 27 citations

The effect of ethanol on membranes

1985 • 27 citations

The Interaction of Ethanol, Dietary Lipids and Proteins on the Rat Pancreas

1971 • 26 citations

Action of Intragastric Ethanol on the Pancreatic Secretion of Conscious Rats

1975 • 26 citations

Alcoholic pancreatitis in rats fed ethanol in a nutritionally adequate liquid diet

1987 • 24 citations

Ethanol-induced alterations in pancreatic blood flow in conscious dogs.

1982 • 24 citations

Cholesterol esters and membrane permeability. A nuclear magnetic resonance (NMR) study

1977 • 23 citations

Does alcohol cause duodenitis?

1969 • 21 citations

Irreversible inhibition by acetaldehyde of cholecystokinin-induced amylase secretion from isolated rat pancreatic acini

1985 • 21 citations

Pancreatic secretion stimulated by the action of alcohol on the gastric antrum

1968 • 21 citations

Disease of the Pancreas. Its Cause and Nature.

1911 • 20 citations

Pancreatic basal secretion in alcohol-fed and normal dogs

1981 • 20 citations

Relationship between diet, ethyl alcohol consumption and some activities of the exocrine pancreas in rats.

1965 • 20 citations

A Toxic‐Metabolic Hypothesis of Pathogenesis of Alcoholic Pancreatitis

1977 • 19 citations

New technique for the isolation of functional rat pancreatic mitochondria and its application to models of pancreatic injury.

1986 • 19 citations

Studies of Hemorrhagic Pancreatitis in Germ-Free Dogs

1968 • 18 citations

The Effect of Chronic Intragastric Alcohol Ingestion on the Pancreatic Secretion of the Rat

1976 • 17 citations

Transport and exchange diffusion of amino acids by invitro preparations of pancreas from normal, tumor-bearing and alcohol-treated mice

1968 • 17 citations

Effect of Intravenous Injection of Ethyl Alcohol on Gastric Secretion in Man.

1932 • 16 citations

Pancreatic Exocrine Secretion in the Rat after Chronic Alcohol Ingestion: Nonparallel Secretion of Proteins and Pancreatic Secretory Trypsin Inhibitor

1979 • 16 citations

THE PRESSURE OF PANCREATIC SECRETION, AND THE MODE OF ABSORPTION OF PANCREATIC JUICE AFTER OBSTRUCTION OF THE MAIN DUCTS OF THE PANCREAS

1909 • 16 citations

Influence of ethanol on pancreatic lipid metabolism.

1980 • 16 citations

Acute pancreatitis and hyperdiastasuria after partial gastrectomy.

1958 • 15 citations

Acute and Chronic Pancreatitis

1974 • 15 citations

STUDIES ON THE DEVELOPMENT OF PANCREATIC NECROSIS IN THE LIVING MOUSE.

1964 • 14 citations

The effect of alcohol on pancreatic secretion.

1960 • 14 citations

Duodenal pressure as a factor in the cause of pancreatitis.

1970 • 14 citations

Dietary carbohydrate level determines the effect of long-term ethanol ingestion on rat pancreatic amylase content.

1986 • 13 citations

Attempted Visualization of the Pancreatic Ducts by Ampullary Reflux

1955 • 12 citations

Chronic calcifying pancreatitis (CCP). Mechanism of formation of the lesions. New data and critical study.

1980 • 12 citations

[Ethanol metabolism by rat pancreas. I. Presence and level modifications of ethanol oxidizing systems (author's transl)].

1977 • 12 citations

Further studies of the ethanol-induced changes in pancreatic lipid metabolism

1980 • 11 citations

Effects of ethanol,dl-Ethionine, and protein deficiency on rat pancreas

1970 • 11 citations

Effect of chronic ethanol consumption on the pancreas of the hamster

1985 • 10 citations

Chronic ethanol feeding causes accumulation of serum cholesterol in rat pancreas

1984 • 9 citations

An experimental study of pancreatitis following Polya gastrectomy.

1963 • 9 citations

Effect of chronic feeding of ethanol diet of ?average? fat content on rat pancreas

1987 • 9 citations

Duodenal reflux in the genesis of acute pancreatitis.

1967 • 9 citations

Abstracts

1980 • 8 citations

Decrease in arachidonoyl-containing phosphatidylinositols in pancreas of rats fed an ethanol-containing diet

1984 • 8 citations

Modification by Sex of Diet and Ethanol Effect on Rat Pancreatic Acinar Cell Metabolism

1986 • 7 citations

Effect of alcohol on duodenal-pancreatic reflux

1973 • 7 citations

Papillary integrity as a factor in pancreatic reflux

1971 • 6 citations

Lipogenetic effects of ethanol and ethanol metabolism in the rat pancreas in vitro [proceedings].

1979 • 1 citations