Endothelial Activation and Inflammation

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells.

1984 • 944 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migration.

1988 • 626 citations

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

1986 • 592 citations

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2.

1986 • 534 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

1983 • 487 citations

Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains

1989 • 428 citations

Interleukin 1 and lipopolysaccharide induce an inhibitor of tissue-type plasminogen activator in vivo and in cultured endothelial cells.

1986 • 414 citations

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.

1986 • 401 citations

Induction and detection of a human endothelial activation antigen in vivo.

1986 • 378 citations

Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.

1986 • 326 citations

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1.

1986 • 325 citations

Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers.

1986 • 296 citations

Interleukin-1 activation of vascular endothelium. Effects on procoagulant activity and leukocyte adhesion.

1985 • 295 citations

Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome.

1986 • 275 citations

Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice.

1988 • 260 citations

Immunoglobulin M antibodies present in the acute phase of Kawasaki syndrome lyse cultured vascular endothelial cells stimulated by gamma interferon.

1986 • 244 citations

Acute Inflammation and Microthrombosis Induced by Endotoxin, Interleukin-1, and Tumor Necrosis Factor and their Implication in Gram-Negative Infection

1989 • 230 citations

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome.

1988 • 225 citations

Endothelial Adhesiveness for Blood Neutrophils Is Inhibited by Transforming Growth Factor-β

1988 • 224 citations

Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury.

1987 • 214 citations

The immunopathology of experimental allergic encephalomyelitis. II. Endothelial cell Ia increases prior to inflammatory cell infiltration.

1984 • 198 citations

Lymphocyte recruitment in delayed-type hypersensitivity. The role of IFN-gamma.

1988 • 170 citations

Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas.

1988 • 163 citations

Effects of cytokines on vascular endothelium: Their role in vascular and immune injury

1989 • 161 citations

Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.

1986 • 145 citations

Studies on the adhesive interaction between purified human eosinophils and cultured vascular endothelial cells.

1988 • 144 citations

Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons.

1988 • 142 citations

IL-1 and IFN-gamma increase vascular permeability.

1988 • 131 citations

The role of interleukin-1 in neutrophil leukocyte emigration induced by endotoxin.

1986 • 128 citations

Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor

1988 • 112 citations

Interferon gamma induces synthesis of complement alternative pathway proteins by human endothelial cells in culture.

1988 • 104 citations

Tumor necrosis factor enhances susceptibility of vascular endothelial cells to neutrophil-mediated killing.

1988 • 90 citations

IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis.

1989 • 83 citations

Expression of I-region-associated antigen (Ia) and interleukin 1 by subcultured human endothelial cells

1985 • 72 citations

Adherence of human basophils to cultured umbilical vein endothelial cells.

1988 • 68 citations

Cultured human endothelial cells stimulated with cytokines or endotoxin produce an inhibitor of leukocyte adhesion.

1988 • 58 citations

Polymorphonuclear leukocyte-dependent plasma leakage in the rabbit skin is enhanced or inhibited by prostacyclin, depending on the route of administration.

1986 • 51 citations

Antibodies to guinea pig lymphokines. II. Suppression of delayed hypersensitivity reactions by a "second generation" goat antibody against guinea pig lymphokines.

1976 • 47 citations

Endothelial Activation

1988 • 38 citations

Tumor necrosis factor and immune interferon act in concert to slow the lateral diffusion of proteins and lipids in human endothelial cell membranes.

1988 • 29 citations

Antibodies to Guinea Pig Lymphokines

1976 • 27 citations