Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

The Pharmacological Basis of Therapeutics

1986 • 1,413 citations

CONTRIBUTION TO THE KNOWLEDGE OF SARCOMA

1891 • 656 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.

1983 • 458 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

STUDIES ON THE GENERALIZED SHWARTZMAN REACTION

1952 • 300 citations

CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY

1968 • 298 citations

Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo.

1987 • 292 citations

Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells.

1982 • 272 citations

Tumour necrosis factor and lymphotoxin genes map close to H–2D in the mouse major histocompatibility complex

1987 • 230 citations

Serum-free in vitro bioassay for the detection of tumor necrosis factor

1986 • 195 citations

STUDIES ON THE MECHANISM OF THE SHWARTZMAN PHENOMENON

1951 • 144 citations

STUDIES ON THE MECHANISM OF THE SHWARTZMAN PHENOMENON

1949 • 122 citations

Interleukin 1: a common endogenous mediator of inflammation and the local Shwartzman reaction.

1986 • 119 citations

High Susceptibility of Strain A Mice to Endotoxin and Endotoxin-Red Blood Cell Mixtures

1965 • 107 citations

In vitro synergism between interferons and human lymphotoxin: enhancement of lymphotoxin-induced target cell killing.

1983 • 64 citations

The Inflammatory Response and Resistance to Endotoxin in Mice

1978 • 39 citations