IMPROVED AORTOCORONARY BYPASS PATENCY BY LOW-DOSE ASPIRIN (100 mg DAILY)

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASE

1955 • 2,755 citations

Protective Effects of Aspirin against Acute Myocardial Infarction and Death in Men with Unstable Angina

1983 • 1,740 citations

Selective Cumulative Inhibition of Platelet Thromboxane Production by Low-dose Aspirin in Healthy Subjects

1982 • 940 citations

Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.

1983 • 675 citations

A Platelet-Inhibitor-Drug Trial in Coronary-Artery Bypass Operations

1982 • 550 citations

Effect of Dipyridamole and Aspirin on Late Vein-Graft Patency after Coronary Bypass Operations

1984 • 529 citations

Differential Inhibition by Aspirin of Vascular and Platelet Prostaglandin Synthesis in Atherosclerotic Patients

1983 • 460 citations

Aspirin Use in Patients with Major Upper Gastrointestinal Bleeding and Peptic-Ulcer Disease

1974 • 304 citations

DIFFERENTIAL INHIBITION OF PROSTACYCLIN PRODUCTION AND PLATELET AGGREGATION BY ASPIRIN

1979 • 284 citations

Coronary bypass surgery for chronic angina--1981. A perspective.

1982 • 251 citations

Prevention of Thrombosis in Patients on Hemodialysis by Low-Dose Aspirin

1979 • 248 citations

DIFFERENTIAL INHIBITION BY LOW-DOSE ASPIRIN OF HUMAN VENOUS PROSTACYCLIN SYNTHESIS AND PLATELET THROMBOXANE SYNTHESIS

1981 • 200 citations

Vein graft patency and intimal proliferation after aortocoronary bypass: Early and long-term angiopathologic correlations

1976 • 198 citations

Failure of Antiplatelet and Anticoagulant Therapy to Improve Patency of Grafts after Coronary-Artery Bypass

1979 • 171 citations

A Controlled Comparison of Aspirin and Oral Anticoagulants in Prevention of Death after Myocardial Infarction

1982 • 134 citations

The effect of antithrombotic therapy on patency rates of saphenous vein coronary artery bypass grafts

1982 • 133 citations

Aspirin- and Coumadin®-Related Bleeding After Coronary-Artery Bypass Graft Surgery

1978 • 130 citations

Reduction of intimal thickening in canine coronary bypass vein grafts with dipyridamole and aspirin

1979 • 129 citations

Influence of Aspirin and Dipyridamole on Patency of Coronary Artery Bypass Grafts

1981 • 109 citations

Noninvasive radioisotopic technique for detection of platelet deposition in coronary artery bypass grafts in dogs and its reduction with platelet inhibitors.

1979 • 99 citations

Improved graft patency with anticoagulant therapy after aortocoronary bypass surgery: a prospective, randomized study.

1981 • 80 citations

Effects of sulfinpyrazone on early graft closure after myocardial revascularization

1982 • 68 citations

Stimulated Platelet Aggregation, Thromboxane B2 Formation and Platelet Sensitivity to Prostacyclin - A Critical Evaluation

1981 • 62 citations

A regimen for low-dose aspirin?

1982 • 53 citations

Correlation of platelet survival time with occlusion of saphenous vein aorto-coronary bypass grafts.

1976 • 43 citations

Improved graft patency with antiplatelet drugs in patients treated for one year following coronary bypass surgery

1981 • 32 citations

Influence of intracoronary platelet aggregation on ventricular electrical properties during partial coronary artery stenosis

1983 • 32 citations

Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man

1981 • 28 citations

Low-dose aspirin (ASA) renders human platelets more vulnerable to inhibition of aggregation by prostacyclin (PGI2)

1983 • 15 citations