Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1962 • 4,273 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Serum Cholesterol, Lipoproteins, and the Risk of Coronary Heart Disease

1971 • 2,055 citations

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

1971 • 1,535 citations

A Randomized Trial of Aspirin and Sulfinpyrazone in Threatened Stroke

1978 • 933 citations

Platelet Function in Hyperlipoproteinemia

1974 • 682 citations

Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets

1977 • 601 citations

Inhibition of platelet prostaglandin synthetase by oral aspirin.

1978 • 552 citations

PLATELET-MEMBRANE FATTY ACIDS, PLATELET AGGREGATION, AND THROMBOXANE FORMATION DURING A MACKEREL DIET

1980 • 551 citations

A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction

1974 • 517 citations

Platelet and Fibrinogen Consumption in Man

1972 • 492 citations

UNSTABLE METABOLITES OF ARACHIDONIC ACID AND THEIR ROLE IN HAEMOSTASIS AND THROMBOSIS

1978 • 447 citations

The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3′:5′-cyclic monophosphate in platelets

1971 • 422 citations

Selective release of archidonic acid from the phospholipids of human platelets in response to thrombin.

1977 • 409 citations

DIPYRIDAMOLE AND OTHER PHOSPHODIESTERASE INHIBITORS ACT AS ANTITHROMBOTIC AGENTS BY POTENTIATING ENDOGENOUS PROSTACYCLIN

1978 • 392 citations

Pharmacologic Control of Thromboembolic Complications of Cardiac-Valve Replacement

1971 • 353 citations

Sulfinpyrazone in the Prevention of Sudden Death after Myocardial Infarction

1980 • 335 citations

Increased platelet aggregation in diabetes mellitus.

1982 • 325 citations

Increased Platelet Aggregation in Early Diabetus Mellitus

1975 • 314 citations

Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

1979 • 310 citations

Prevention of Thrombosis in Patients on Hemodialysis by Low-Dose Aspirin

1979 • 248 citations

PLATELET ACTIVATION IN ACUTE CEREBRAL ISCHÆMIA

1977 • 177 citations

Failure of Antiplatelet and Anticoagulant Therapy to Improve Patency of Grafts after Coronary-Artery Bypass

1979 • 171 citations

Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina

1979 • 164 citations

Platelet Activation during Exercise-Induced Myocardial Ischemia

1980 • 161 citations

Influence of a Pyrimidopyrimidine Derivative on Deamination of Adenosine by Blood

1964 • 160 citations

Effects of sulfinpyrazone on platelet prostaglandin synthesis and platelet release of serotonin.

1977 • 130 citations

Effect of Smoking on Blood Coagulation and Platelet Survival in Man

1963 • 126 citations

Platelet abnormalities in ischemic heart disease

1973 • 112 citations

Platelet Survival and Adhesiveness in Recurrent Venous Thrombosis

1973 • 95 citations

A randomized, controlled trial of aspirin in persons recovered from myocardial infarction

1980 • 89 citations

Effects of aspirin and dipyridamole on the degradation of adenosine diphosphate by cultured cells derived from bovine pulmonary artery.

1980 • 89 citations

Movement of sodium into human platelets induced by ADP

1977 • 72 citations

Rapid inactivation of cyclooxygenase activity after stimulation of intact platelets

1979 • 72 citations

Prostacyclin (PGI2) and thromboxane A2 interaction in vivo. Regulation by aspirin and relationship with anti-thrombotic therapy

1978 • 60 citations

Increased platelet adhesiveness in hypertensive cardiovascular disease

1968 • 48 citations

Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function.

1980 • 46 citations

Effects of dipyridamole in experimental atherosclerosis

1979 • 31 citations

Two new metabolites of sulfinpyrazone in the rabbit: A possible cause of the prolonged effect

1979 • 28 citations