Detection of Noncarboxymethyllysine and Carboxymethyllysine Advanced Glycation End Products (AGE) in Serum of Diabetic Patients

Protein Purification by Affinity Chromatography

1970 • 2,809 citations

Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications

1988 • 2,527 citations

Structure Elucidation of a Senescence Cross-Link from Human Extracellular Matrix

1989 • 1,056 citations

Advanced Glycosylation End Products in Patients with Diabetic Nephropathy

1991 • 925 citations

Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.

1986 • 830 citations

The Advanced Glycation End Product, N∊-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and Glycoxidation Reactions

1996 • 780 citations

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

1997 • 701 citations

Accelerated age-related browning of human collagen in diabetes mellitus.

1984 • 671 citations

N.epsilon.-(Carboxymethyl)lysine Is a Dominant Advanced Glycation End Product (AGE) Antigen in Tissue Proteins

1995 • 518 citations

Immunochemical detection of advanced glycosylation end products in vivo.

1992 • 496 citations

An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

1996 • 466 citations

N^ε-(Carboxymethyl)lysine Protein Adduct Is a Major Immunological Epitope in Proteins Modified with Advanced Glycation End Products of the Maillard Reaction

1996 • 427 citations

Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure

1994 • 374 citations

Aging of Proteins: Immunological Detection of a Glucose-derived Pyrrole Formed during Maillard Reaction in vivo

1989 • 302 citations

Age-dependent accumulation of N.epsilon.-(carboxymethyl)lysine and N.epsilon.-(carboxymethyl)hydroxylysine in human skin collagen

1991 • 298 citations

Hemoglobin-AGE: A Circulating Marker of Advanced Glycosylation

1992 • 255 citations

Immunohistochemical detection of imidazolone, a novel advanced glycation end product, in kidneys and aortas of diabetic patients.

1997 • 190 citations

Immunological quantification of advanced glycosylation end-products in the serum of patients on hemodialysis or CAPD

1994 • 142 citations

Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes.

1997 • 138 citations

Crosslines A and B as candidates for the fluorophores in age- and diabetes-related cross-linked proteins, and their diacetates produced by Maillard reaction of α-N-acetyl-<scp>L</scp>-lysine with<scp>D</scp>-glucose

1992 • 98 citations

Long-term assessment of glucose control by haemoglobin-AGE measurement

1996 • 91 citations

The advanced glycation end product Nepsilon-(carboxymethyl)lysine is increased in serum from children and adolescents with type 1 diabetes.

1998 • 90 citations

Production and characterization of antibodies to advanced glycation products on proteins

1989 • 61 citations