Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disorders.

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

Response of a Protein Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect

1992 • 933 citations

Interior and surface of monomeric proteins

1987 • 924 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

1990 • 549 citations

Crystal structure of an HIV-binding recombinant fragment of human CD4

1990 • 545 citations

Structure of a Fibronectin Type III Domain from Tenascin Phased by MAD Analysis of the Selenomethionyl Protein

1992 • 500 citations

The three-dimensional structure of the tenth type III module of fibronectin: An insight into RGD-mediated interactions

1992 • 472 citations

Many of the Immunoglobulin Superfamily Domains in Cell Adhesion Molecules and Surface Receptors Belong to a New Structural Set Which is close to That Containing Variable Domains

1994 • 439 citations

X–linked spastic paraplegia (SPG1), MASA syndrome and X–linked hydrocephalus result from mutations in the L1 gene

1994 • 426 citations

Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1

1989 • 390 citations

Aberrant splicing of neural cell adhesion molecule L1 mRNA in a family with X–linked hydrocephalus

1992 • 319 citations

Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity

1996 • 298 citations

Evolution of proteins formed by β-sheets

1982 • 275 citations

Functions of fibroblast growth factors and their receptors

1995 • 254 citations

Crystal structure of the tenth type III cell adhesion module of human fibronectin

1994 • 207 citations

Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules.

1991 • 190 citations

Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution

1995 • 187 citations

Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily.

1992 • 161 citations

Structure of the chicken neuron-glia cell adhesion molecule, Ng-CAM: origin of the polypeptides and relation to the Ig superfamily.

1991 • 160 citations

MASA syndrome is due to mutations in the neural cell adhesion gene L1CAM

1994 • 155 citations

Molecular structure and functional testing of human L1CAM: An interspecies comparison

1991 • 154 citations

Structural and Energetic Responses to Cavity-Creating Mutations in Hydrophobic Cores: Observation of a Buried Water Molecule and the Hydrophilic Nature of Such Hydrophobic Cavities

1996 • 147 citations

X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 Å resolution

1992 • 146 citations

Crystal Structure of Domains 3 and 4 of Rat CD4: Relation to the NH₂-Terminal Domains

1993 • 142 citations

Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1 Two L1 isoforms in the cytoplasmic region are produced by differential splicing

1991 • 110 citations

Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set

1995 • 108 citations

Crystal structure of tandem type III fiibronectin domains from drosophila neuroglian at 2.0 å

1994 • 104 citations

X linked hydrocephalus and MASA syndrome.

1996 • 94 citations

Immunoglobulin-Type Domains of Titin: Same Fold, Different Stability?

1994 • 82 citations

Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA

1992 • 82 citations

Members of the immunoglobulin superfamily in bacteria

1996 • 67 citations

New domains of neural cell-adhesion molecule L1 implicated in X-linked hydrocephalus and MASA syndrome.

1995 • 66 citations

Zebrafish neurons express two L1‐related molecules during early axonogenesis

1995 • 66 citations

Gene analysis of L1 neural cell adhesion molecule in prenatal diagnosis of hydrocephalus

1995 • 61 citations

The gene encoding L1, a neural adhesion molecule of the immunoglobulin family, is located on the X chromosome in mouse and man

1990 • 61 citations

X-linked hydrocephalus and MASA syndrome present in one family are due to a single missense mutation in exon 28 of the L1CAM gene

1994 • 54 citations

Mutations in L1-CAM in two families with X linked complicated spastic paraplegia, MASA syndrome, and HSAS.

1995 • 49 citations

Differential Effects of Two Hydrocephalus/MASA Syndrome-related Mutations on the Homophilic Binding and Neuritogenic Activities of the Cell Adhesion Molecule L1

1996 • 32 citations

Identification of a 5' splice site mutation in intron 4 of the L1CAM gene in an X-linked hydrocephalus family

1994 • 31 citations

Five novel mutations in the L1CAM gene in families with X linked hydrocephalus.

1996 • 27 citations

Outline structures for the extracellular domains of the fibroblast growth factor receptors

1995 • 23 citations

Discordant segregation of Xq28 markers and a mutation in the L1 gene in a family with X linked hydrocephalus.

1996 • 17 citations

A deletion of five nucleotides in the LICAM gene in a Japanese family with X-linked hydrocephalus

1996 • 14 citations