Interactions between ascorbyl free radical and coenzyme Q at the plasma membrane.

[6] Quantitation of protein

1990 • 1,401 citations

Biology of free radical scavengers: an evaluation of ascorbate

1993 • 482 citations

Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity.

1990 • 461 citations

Ascorbic Acid: Chemistry, Metabolism, and Uses

1982 • 453 citations

The role of ascorbate in antioxidant protection of biomembranes: Interaction with vitamin E and coenzyme Q

1994 • 402 citations

Reduction of Dehydroascorbate to Ascorbate by the Selenoenzyme Thioredoxin Reductase

1997 • 331 citations

The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems.

1996 • 306 citations

Interaction of vitamin C and vitamin E during free radical stress in plasma: An ESR study

1993 • 243 citations

Electron spin resonance spectra of radical intermediates in the oxidation of ascorbic acid and related substances

1972 • 240 citations

Requirement for coenzyme Q in plasma membrane electron transport.

1992 • 215 citations

Vitamin E recycling in human erythrocyte membranes

1993 • 204 citations

Is ascorbic acid an antioxidant for the plasma membrane?

1999 • 203 citations

Ascorbate recycling in human erythrocytes: Role of GSH in reducing dehydroascorbate

1996 • 195 citations

Reduction of the Ascorbyl Free Radical to Ascorbate by Thioredoxin Reductase

1998 • 186 citations

Transport of ascorbic acid and other water-soluble vitamins

1988 • 179 citations

Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport.

1995 • 172 citations

Oxidoreduction at the plasma membrane : relation to growth and transport

1990 • 130 citations

Vitamin E and selenium deficiency induces expression of the ubiquinone‐dependent antioxidant system at the plasma membrane

1998 • 130 citations

Purification of NADPH-dependent dehydroascorbate reductase from rat liver and its identification with 3α-hydroxysteroid dehydrogenase

1994 • 113 citations

DT-Diaphorase Maintains the Reduced State of Ubiquinones in Lipid Vesicles thereby Promoting their Antioxidant Function

1997 • 104 citations

Tissue, Subcellular, and Submitochondrial Distributions of Semidehydroascorbate Reductase: Possible Role of Semidehydroascorbate Reductase in Cofactor Regeneration

1982 • 104 citations

Two Homologous Cytochromes b₅ in a Single Cell

1983 • 95 citations

Studies with Ubiquinone‐Depleted Submitochondrial Particles

1974 • 93 citations

Direct spectrophotometric detection of ascorbate free radical formed by dopamine β-monooxygenase and by ascorbate oxidase

1980 • 92 citations

Enzyme-Dependent Ascorbate Recycling in Human Erythrocytes: Role of Thioredoxin Reductase

1998 • 91 citations

Isolation of purified plasma membranes from cultured cells and hepatomas by two-phase partition and preparative free-flow electrophoresis.

1989 • 86 citations

Ascorbate-quinone interactions: electrochemical, free radical, and cytotoxic properties.

1983 • 84 citations

Interaction of Ascorbate and α-Tocopherol in Resealed Human Erythrocyte Ghosts

1996 • 83 citations

A Phospholipid-Dependent NADH-Coenzyme Q Reductase from Liver Plasma Membrane

1995 • 81 citations

Ascorbate Stimulates Ferricyanide Reduction in HL-60 Cells through a Mechanism Distinct from the NADH-dependent Plasma Membrane Reductase

1998 • 80 citations

Ascorbate is regenerated by HL-60 cells through the transplasmalemma redox system

1991 • 79 citations

Enzymatic recycling of oxidized ascorbate in pig heart: One-electron vs two-electron pathway

1991 • 78 citations

Antioxidant ascorbate is stabilized by NADH-coenzyme Q10 reductase in the plasma membrane.

1997 • 76 citations

Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. No spin-trapping evidence for the hydroxyl radical in iron-overloaded plasma

1992 • 75 citations

Interactions between ubiquinones and vitamins in membranes and cells

1994 • 74 citations

Genetic evidence for coenzyme Q requirement in plasma membrane electron transport.

1998 • 55 citations

A novel point mutation in a 3' splice site of the NADH-cytochrome b5 reductase gene results in immunologically undetectable enzyme and impaired NADH-dependent ascorbate regeneration in cultured fibroblasts of a patient with type II hereditary methemoglobinemia.

1995 • 53 citations

Coenzyme Q6 and Iron Reduction Are Responsible for the Extracellular Ascorbate Stabilization at the Plasma Membrane of Saccharomyces cerevisiae

1998 • 52 citations

Growth factor‐stimulated trans plasma membrane electron transport in HL‐60 cells

1992 • 47 citations

[17] Preparation of membrane fractions

1990 • 44 citations

NADH-ascorbate free radical and -ferricyanide reductase activities represent different levels of plasma membrane electron transport

1993 • 40 citations

Plasma membrane redox activity correlates with N‐myc expression in neuroblastoma cells

1992 • 37 citations

Ascorbate-dependent electron transfer across the human erythrocyte membrane

1999 • 36 citations

Interaction of the 2,6-dimethoxysemiquinone and ascorbyl free radicals with Ehrlich ascites cells: a probe of cell-surface charge.

1984 • 34 citations

Vitamin C recycling and function in human monocytic U-937 cells

1999 • 33 citations

Determination of the Ascorbate Free Radical Concentration in Mixtures of Ascorbate and Dehydroascorbate

1998 • 33 citations

Cell surface glycoconjugates control the activity of the NADH-ascorbate free radical reductase of rat liver plasma membrane

1988 • 33 citations

Ascorbate‐mediated transmembrane electron transport and ascorbate uptake in leukemic cell lines are two different processes

1992 • 32 citations

Ubiquinol regeneration by plasma membrane ubiquinone reductase

1998 • 29 citations

NADH-monodehydroascorbate reductase in human erythrocyte membranes.

1983 • 28 citations

Kinetic behavior of the monodehydroascorbate radical studied by pulse radiolysis

1991 • 27 citations

Extracellular ascorbate stabilization: Enzymatic or chemical process?

1994 • 25 citations

Enzyme-controlled scavenging of ascorbyl and 2,6-dimethoxy-semiquinone free radicals in Ehrlich ascites tumor cells.

1985 • 24 citations

Ceruloplasmin stimulates NADH oxidation of pig liver plasma membrane

1992 • 23 citations

No enzymatic activities are necessary for the stabilization of ascorbic acid by K‐562 cells

1993 • 17 citations

Electron spin resonance study on the formation of ascorbate free radical from ascorbate: The effect of dehydroascorbic acid and ferricyanide

1998 • 16 citations

Extracellular ascorbate stabilization as a result of transplasma electron transfer inSaccharomyces cerevisiae

1995 • 16 citations

A plasma membrane redox system in human retinoblastoma cells.

1993 • 15 citations

Reduction of ubiquinone-1 by ascorbic acid is a catalytic and reversible process controlled by the concentration of molecular oxygen

1996 • 15 citations

Reduction of extracellular dehydroascorbic acid by K562 cells

1996 • 15 citations

Modes of coenzyme Q function in electron transfer

1995 • 14 citations