Early Embryology of the Vertebrate Ear

Handbook of Sensory Physiology

1975 • 7,212 citations

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

The Handbook of brain theory and neural networks

1996 • 3,654 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila

1995 • 1,563 citations

Normal Table of Xenopus Laevis.

1968 • 1,185 citations

Patterning the Vertebrate Neuraxis

1996 • 1,151 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

The triple origin of skull in higher vertebrates: a study in quail-chick chimeras

1993 • 981 citations

Handbuch der vergleichenden Anatomie der Wirbeltiere

1931 • 748 citations

Contributions to Sensory Physiology

1965 • 717 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Contributions of placodal and neural crest cells to avian cranial peripheral ganglia

1983 • 684 citations

Development of the inner ear of the mouse: a radioautographic study of terminal mitoses.

1967 • 679 citations

The Genesis of Neural Crest and Epidermal Placodes: A Reinterpretation of Vertebrate Origins

1983 • 676 citations

A type VII myosin encoded by the mouse deafness gene shaker-1

1995 • 674 citations

Local application of retinoic acid to the limb bond mimics the action of the polarizing region

1982 • 669 citations

Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene

1994 • 661 citations

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3

1994 • 635 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

Combinatorial expression of three zebrafish genes related to distal- less: part of a homeobox gene code for the head

1994 • 607 citations

Pax2 contributes to inner ear patterning and optic nerve trajectory

1996 • 588 citations

Roles of Pax-genes in developing and adult brain as suggested by expression patterns

1994 • 582 citations

Fibroblast growth factors induce additional limb development from the flank of chick embryos

1995 • 578 citations

Archetypal organization of the amphioxus Hox gene cluster

1994 • 574 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6

1992 • 537 citations

Hereditary Hearing Loss and its Syndromes

1995 • 502 citations

In Vitro Studies

1992 • 502 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Complementary roles of BDNF and NT-3 in vestibular and auditory development

1995 • 465 citations

Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity

1992 • 461 citations

Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death

1992 • 458 citations

The Evolutionary Biology of Hearing

1996 • 451 citations

Mice homozygous for a targeted disruption of the proto-oncogeneint-2have developmental defects in the tail and inner ear

1993 • 446 citations

Analysis of development

1955 • 432 citations

Contributions to sensory physiology

1965 • 426 citations

Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor.

1992 • 417 citations

Another role for melanocytes: their importance for normal stria vascularis development in the mammalian inner ear

1989 • 405 citations

Pax in development

1992 • 402 citations

Spatially and temporally restricted expression of Pax2 during murine neurogenesis

1990 • 397 citations

The evolutionary biology of hearing

1992 • 394 citations

The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor

1994 • 391 citations

Two rhombomeres are altered in Hoxa-1 mutant mice

1993 • 391 citations

Mutations affecting development of the zebrafish retina.

1996 • 367 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

Distal Regeneration and Symmetry

1981 • 352 citations

Development of Auditory and Vestibular Systems

1983 • 351 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain

1993 • 340 citations

Evolution and role of Pax genes

1993 • 337 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 326 citations

Early ear development in the embryo of the Zebrafish,Danio rerio

1996 • 318 citations

Respecification of vertebral identities by retinoic acid

1992 • 312 citations

Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development

1989 • 309 citations

Organization of Olivocochlear Efferent Systems in Mammals

1992 • 303 citations

Mutations affecting development of the zebrafish inner ear and lateral line

1996 • 301 citations

The embryonic and postnatal development of the inner ear of the mouse.

1971 • 293 citations

Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia.

1992 • 293 citations

Ontogeny of Structure and Function in the Vertebrate Auditory System

1978 • 290 citations

Inductive Processes in Embryonic Development

1966 • 287 citations

The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification

1993 • 285 citations

Features of embryonic induction

1988 • 271 citations

Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain

1993 • 260 citations

Actin filaments, stereocilia, and hair cells of the bird cochlea

1986 • 256 citations

Expression pattern of zebrafish pax genes suggests a role in early brain regionalization

1991 • 255 citations

Mutations in the paired domain of the human PAX3 gene cause Klein-Waardenburg syndrome (WS-III) as well as Waardenburg syndrome type I (WS-I).

1993 • 250 citations

Neuronal determination without cell division in xenopus embryos

1991 • 246 citations

The cellular basis of the convergence and extension of the Xenopus neural plate

1992 • 239 citations

Coordinate embryonic expression of three zebrafish engrailed genes

1992 • 236 citations

Embryonic expression and cloning of the murine GATA-3 gene

1994 • 233 citations

Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos

1991 • 229 citations

Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development

1994 • 227 citations

Developmental biology

1992 • 224 citations

An amphioxus homeobox gene: sequence conservation, spatial expression during development and insights into vertebrate evolution

1992 • 206 citations

From white spots to stem cells: the role of the Kit receptor in mammalian development

1993 • 206 citations

The early development of cranial sensory ganglia and the potentialities of their component cells studied in quail-chick chimeras

1982 • 205 citations

Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation

1994 • 204 citations

valentino: a zebrafish gene required for normal hindbrain segmentation

1996 • 203 citations

Sensory Organ Generation in the Chick Inner Ear

1996 • 198 citations

Vertebrate Craniofacial Development: The Relation between Ontogenetic Process and Morphological Outcome; pp. 190–207

1991 • 197 citations

Developmental and Evolutionary Aspects of the Neural Crest

1988 • 196 citations

Pax: Gene regulators in the developing nervous system

1993 • 195 citations

The Evolution of Vertebrate Hearing

1967 • 192 citations

The kreisler mouse: a hindbrain segmentation mutant that lacks tworhombomeres

1994 • 184 citations

The int-2 proto-oncogene is responsible for induction of the inner ear

1991 • 181 citations

Early development and innervation of taste bud‐bearing papillae on the rat tongue

1991 • 180 citations

Multiple roles for FGF-3 during cranial neural development in the chicken

1995 • 176 citations

Taste receptor cells arise from local epithelium, not neurogenic ectoderm.

1995 • 174 citations

Cell fate specification in the inner ear

1996 • 173 citations

Hox Genes and Regionalization of the Nervous System

1994 • 172 citations

Conservation of Neuroepithelial and Mesodermal Segments in the Embryonic Vertebrate Head

1993 • 172 citations

Regional expression of three homeobox transcripts in the inner ear of zebrafish embryos

1992 • 171 citations

Temporal patterns of neurogenesis in avian cranial sensory and autonomic ganglia

1982 • 171 citations

The initiation of the limb bud: Growth factors, Hox genes, and retinoids

1995 • 170 citations

Retinoic acid and craniofacial development: Molecules and morphogenesis

1993 • 165 citations

The biology of change in otolaryngology

1988 • 165 citations

Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis.

1991 • 163 citations

Pax-2 is a DNA-binding protein in embryonic kidney and Wilms tumor

1992 • 162 citations

Differential Expression of Bone Morphogenetic Proteins in the Developing Vestibular and Auditory Sensory Organs

1996 • 162 citations

Correlation of the development of membranous and bony labyrinths, acoustic ganglia, nerves, and brain centers of the chick embryo

1967 • 161 citations

Development of Auditory and Vestibular Systems 2

1993 • 160 citations

Kidney and Retinal Defects (Krd), a Transgene-Induced Mutation with a Deletion of Mouse Chromosome 19 That Includes the Pax2 Locus

1994 • 156 citations

Age-related changes in the C57BL/6J mouse cochlea. II. Ultrastructural findings

1981 • 155 citations

The development of innervation patterns in the avian cochlea

1985 • 150 citations

Development of Sensory Systems

1978 • 148 citations

Ectodermal Placodes Contributions to the Development of the Vertebrate Head

1993 • 146 citations

Cranial and Spinal Nerve Organization in Amphioxus and Lampreys: Evidence for an Ancestral Craniate Pattern

1993 • 145 citations

Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr)

1993 • 144 citations

Quantitative analysis of the innervation of the chicken basilar papilla

1992 • 141 citations

Distribution of synaptic ribbons in the developing organ of Corti

1986 • 140 citations

The development of the neural folds and cranial ganglia of the rat

1925 • 140 citations

Functional Aspects of the Evolution of the Auditory System of Actinopterygian Fish

1992 • 139 citations

The Role of FGF-3 in Early Inner Ear Development: An Analysis in Normal andkreislerMutant Mice

1996 • 139 citations

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction

1992 • 136 citations

Cell production in the chicken cochlea

1989 • 136 citations

Neue Mutationen und Koppelungsgruppen bei der Hausmaus

1942 • 135 citations

Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.

1993 • 133 citations

Zebrafish pax[b] is involved in the formation of the midbrain–hindbrain boundary

1992 • 127 citations

The determination and positioning of the nose, lens and ear. I. Interactions within the ectoderm, and between the ectoderm and underlying tissues

1963 • 126 citations

Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene

1996 • 125 citations

Mutations affecting development of the zebrafish ear

1996 • 125 citations

Of Flies and Fishes

1994 • 123 citations

Organotypic development of the organ of Corti in culture

1975 • 118 citations

Epithelial autonomy in the development of the inner ear of a bird embryo

1990 • 116 citations

Stereociliary bundles reorient during hair cell development and regeneration in the chick cochlea

1991 • 116 citations

Embryonic Origin of Amphibian Taste Buds

1995 • 112 citations

DiI reveals a prenatal arrival of efferents at the differentiating otocyst of mice

1993 • 112 citations

An analysis of induction of the ear from foreign ectoderm in the salamander embryo

1950 • 111 citations

Hyaluronan as a propellant for epithelial movement: the development of semicircular canals in the inner ear ofXenopus

1991 • 111 citations

The abnormalities of the inner ear in kreisler mice

1964 • 111 citations

Expression of nerve growth factor (NGF) receptors in the developing inner ear of chick and rat

1991 • 109 citations

Somitomeres: mesodermal segments of vertebrate embryos

1988 • 107 citations

The fate mapping of the eleventh and twelfth day mouse otocyst: An in vitro study of the sites of origin of the embryonic inner ear sensory structures

1978 • 98 citations

Genes and deafness

1994 • 98 citations

Comparative Anatomy of the Middle Ear

1974 • 96 citations

Expression of cell adhesion molecules during embryonic induction

1987 • 94 citations

Mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene account for a continuous range of phenotypes in human piebaldism.

1992 • 94 citations

A frameshift mutation in the HuP2 paired domain of the probable human homolog of murine Pax-3 is responsible for Waardenburg syndrome type 1 in an Indonesian family

1992 • 93 citations

Retroviral expression of FGF-2 (bFGF) affects patterning in chick limb bud

1993 • 93 citations

Expression patterns of engrailed‐like proteins in the chick embryo

1992 • 92 citations

Reinvestigation of the role of the optic vesicle in embryonic lens induction

1988 • 91 citations

Trophic interactions between the cochleovestibular ganglion of the chick embryo and its synaptic targets in culture

1985 • 91 citations

The inner ear of gymnophione amphibians and its nerve supply: A comparative study of regressive events in a complex sensory system (Amphibia, Gymnophiona)

1988 • 90 citations

Electroreceptors and Mechanosensory Lateral Line Organs Arise from Single Placodes in Axolotls

1995 • 90 citations

Development of the embryonic chick otic placode. II. Electron microscopic analysis

1978 • 86 citations

Embryonic Development of Vestibular Sense Organs and Their Innervation11Research supported by the Swedish Medical Research Council, Project 12X-720.

1983 • 86 citations

Developmental and evolutionary aspects of the neural crest

1987 • 86 citations

The Water-to-Land Transition: Evolution of the Tetrapod Basilar Papilla, Middle Ear, and Auditory Nuclei

1992 • 85 citations

Normal hearing in Splotch (Sp/+), the mouse homologue of Waardenburg syndrome type 1

1992 • 85 citations

Transplantation des OhrblÄschens bei Triton

1925 • 84 citations

Cellular Localization of Brain‐derived Neurotrophic Factor and Neurotrophin‐3 mRNA Expression in the Early Chicken Embryo

1993 • 83 citations

Ganglion formation from the otic placode and the otic crest in the chick embryo: Mitosis, migration, and the basal lamina

1991 • 81 citations

Relations of Symmetry in the Developing Ear of Amblystoma Punctatum

1936 • 81 citations

Delayed neural crest cell emigration from Sp and Sp^d mouse neural tube explants

1990 • 79 citations

The Determination of the Auditory Placode in the Chick

1937 • 79 citations

Anatomical Features of the Inner Ear in Submammalian Vertebrates

1974 • 71 citations

Splotch locus mouse mutants: models for neural tube defects and Waardenburg syndrome type I in humans.

1992 • 69 citations

Cell death during development of the cochlear and vestibular ganglia of the chick

1984 • 65 citations

Characterization of the Homeobox-Containing Gene GH6 Identifies Novel Regions of Homeobox Gene Expression in the Developing Chick Embryo

1994 • 64 citations

The history of the eye muscles

1918 • 63 citations

Electron Microscopic Analysis

1991 • 63 citations

Actin filaments, stereocilia and hair cells of the bird cochlea VI. How the number and arrangement of stereocilia are determined

1992 • 63 citations

Epithelial control of periotic mesenchyme chondrogenesis

1991 • 62 citations

Nerve growth factor and serum differentially regulate development of the embryonic otic vesicle and cochleovestibular ganglion in vitro

1989 • 61 citations

The Efferent Innervation of the Ear: Variations on an Enigma

1992 • 59 citations

Retinoic acid modulation of the early development of the inner ear is associated with the control of c-fos expression

1990 • 59 citations

Development of location‐specific hair cell stereocilia in denervated embryonic ears

1989 • 58 citations

Fiber pathways and positional changes in efferent perikarya of 2.5‐to 7‐day chick embryos as revealed with dil and dextran amiens

1993 • 58 citations

Clinical Aspects of Hearing

1996 • 58 citations

Biochemical and morphological differentiation of acetylcholinesterase‐positive efferent fibers in the mouse cochlea

1990 • 57 citations

9-cis-retinoic acid, a potent inducer of digit pattern duplications in the chick wing bud

1993 • 57 citations

Embryogenesis of the inner ear

1980 • 56 citations

Neuronal Loss in the Spiral Ganglion of Young Rats

1987 • 55 citations

Rhombomere rotation reveals that multiple mechanisms contribute to the segmental pattern of hindbrain neural crest migration

1994 • 54 citations

Untersuchungen an chim�ren von triton und bombinator

1949 • 53 citations

Effects of the Neurotrophins and CNTF on Developing Statoacoustic Neurons: Comparison with an Otocyst-Derived Factor

1993 • 53 citations

The role of the medulla in the differentiation of the otic vesicle

1950 • 52 citations

The labyrinth of Myxine : anatomy, ultrastructure and electrophysiology

1970 • 51 citations

Immunolocalization of basal lamina components during development of chick otic and optic primordia

1993 • 50 citations

The status of the neural segment

1995 • 49 citations

The determination of the otic vesicle in Rana pipiens

1941 • 48 citations

Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum

1994 • 48 citations

Early efferent innervation of the developing rat cochlea studied with a carbocyanine dye

1992 • 48 citations

Self‐differentiation of heterotopic ear ectoderm in the embryo of Amblystoma punctatum

1939 • 46 citations

Morphological and Physiological Development of Vestibular Hair Cells in the Organ-Cultured Otocyst of the Chick

1993 • 45 citations

Embryogenesis of the Inner Ear: “In Vitro Studies”11The studies were supported by grants from the National Institutes of Health (NS08365), the March of Dimes–Birth Defects Foundation (I-375), American Otological Foundation, and the Deafness Research Foundation.22This chapter is dedicated to the memory of Milton Kurtz, deceased March 20, 1981, medical photographer and valued friend.

1983 • 42 citations

X In Vitro Culture of the Isolated Otocyst of the Embryonic Fowl

1956 • 41 citations

Spatiotemporal development of cochlear innervation and hair cell differentiation in the rat

1991 • 41 citations

Development of the Labyrinthine Efferent System^a

1996 • 40 citations

Tropic effects of otic epithelium on cochleo‐vestibular ganglion fiber growth in vitro

1992 • 40 citations

The relation of the developing auditory vesicle to the formation of the cartilage capsule in Amblystoma punctatum

1930 • 38 citations

Development of the lateral line system in Xenopus laevis

1983 • 38 citations

Studies on the development of the ear of amblystoma. Part I.: Development of the auditory vesicle

1892 • 36 citations

The Phylogeny of Octavolateralis Ontogenies: A Reaffirmation of Garstang’s Phylogenetic Hyphothesis

1992 • 36 citations

Transcription factors in inner ear development.

1994 • 36 citations

Culture conditions affect the cholinergic development of an isolated subpopulation of chick mesencephalic neural crest cells

1989 • 34 citations

Primary vestibular projections in the Hagfish,Eptatretus burgeri

1985 • 33 citations

Genetic analyses of mammalian ear development

1992 • 33 citations

Cellular interactions during cartilage and bone development.

1991 • 33 citations

Invagination of the otic placode: Normal development and experimental manipulation

1989 • 31 citations

Development of the lateral line system in Xenopus laevis : II Cell multiplication and organ formation in the supraorbital system

1983 • 31 citations

The History of the Genetics of Hearing Impairment^a

1991 • 30 citations

Tissue Interactions and Growth Factors that Control Development of the Inner Ear

1991 • 29 citations

Development of acoustic ganglia in tissue cultures of embryonic chick otocysts

1965 • 28 citations

Development of the lateral line system in Xenopus laevis. IV. Pattern formation in the supraorbital system.

1985 • 27 citations

Time course of structural changes in regenerating electroreceptors of a weakly electric fish

1990 • 26 citations

Retinoic acid affects the organization of reticulospinal neurons in developing Xenopus

1992 • 25 citations

Genetics of hearing impairment

1991 • 22 citations

Experimental Analyses of the Shaping of the Neural Plate and Tube

1991 • 22 citations

Zur Kopfentwicklung von Bdellostoma

1900 • 22 citations

Innervation of the Organ of Corti of the Fetal Mouse in Culture11This work was supported by NSH Grants NS15061, NS12732, and NS5P30HD03352

1983 • 21 citations

Selective amplification and partial sequencing of cDNAs encoding G protein α subunits from cochlear tissues

1992 • 19 citations

Development of Auditory and Vestibular Systems in Mutant Mice

1983 • 19 citations

Growth factors and development of the stato-acoustic system

1991 • 18 citations

Influences on the Coiling of the Cochlea

1979 • 18 citations

Traces of her workings

1992 • 17 citations

Mouse mutations and human disorders are paired

1992 • 16 citations

An Evaluation of Otopathology in the MOV‐13 Transgenic Mutant Mouse^a

1991 • 14 citations

The development of the inner ear rudiment of the rabbit embryo in a foreign environment

1938 • 12 citations

Evolution of the ancestral vertebrate brain

1998 • 12 citations

Lithium can transform ear placodes ofXenopus into multiple otic vesicles connected by tubes

1990 • 12 citations

Hearing Impairment in Mice with the cmd/cmd (Cartilage Matrix Deficiency) Mutant Gene

1991 • 11 citations

Mapping dysmorphic syndromes with the aid of the human/mouse homology map.

1990 • 10 citations

Ultrastructural Changes of Cochlea in Mice with Hereditary Chondrodysplasia (cho/cho)

1991 • 10 citations

Cellular contacts between hindbrain and prospective ear during inductive interaction in the axolotl embryo

1981 • 7 citations

Approaches to Understanding the Molecular Genetics of Hearing and Deafness

1996 • 5 citations

The Molecular and Structural Basis of Hearing Impairment in Mice with the cpk Mutant Gene

1991 • 2 citations

Expression of Vertebrate Homologs of theDrosophila mshGene during Early Craniofacial Development

1993 • 1 citations