The Inducible Repair of Alkylated DNA

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Genetic studies of the lac repressor

1977 • 610 citations

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1974 • 495 citations

All oxygens in nucleic acids react with carcinogenic ethylating agents

1976 • 311 citations

The properties of in templates for RNA polymerase

1973 • 264 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

1979 • 247 citations

DNA synthesis : present and future

1978 • 226 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Studies on radiation-sensitive mutants of E. coli

1968 • 200 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

1979 • 160 citations

Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase

1980 • 146 citations

Quantitation of the adaptive response to alkylating agents

1979 • 145 citations

Hepatic pathology in rats on low dietary levels of dimethylnitrosamine.

1967 • 127 citations

Screening Tests in Chemical Carcinogenesis

1976 • 115 citations

Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.

1979 • 101 citations

Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents

1978 • 95 citations

Isolation of mutants of Escherichia coli with increased resistance to alkylating agents: Mutants deficient in thiols and mutants constitutive for the adaptive response

1980 • 95 citations

Escherichia coli gene that controls sensitivity to alkylating agents

1978 • 88 citations

Efficiency of the adaptive response of Escherichia coli to alkylating agents

1980 • 61 citations

The adaptive response of E. coli to low levels of alkylating agent: The role of polA in killing adaptation

1978 • 56 citations

The removal of alkylation products from the DNA of Escherichia coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects

1980 • 49 citations

Pathways for repair of DNA damaged by alkylating agent in Escherichia coli

1979 • 44 citations

Screening Tests in Chemical Carcinogenesis

1977 • 40 citations

Mutation and DNA replication in Escherichia coli treated with low concentrations of N-methyl-N′-nitro-N-nitrosoguanidine

1975 • 37 citations

The Leeuwenhoek Lecture, 1978 Bacteria as proper subjects for cancer research

1980 • 11 citations