DNA and redox state induced conformational changes in the DNA-binding domain of the Myb oncoprotein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies

1976 • 1,020 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

1992 • 749 citations

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

1992 • 702 citations

Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.

1991 • 649 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

1989 • 460 citations

Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA

1990 • 378 citations

Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

1990 • 355 citations

Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

1992 • 344 citations

Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene.

1989 • 342 citations

Measurement of protein‐DNA interaction parameters by electrophoresis mobility shift assay

1989 • 262 citations

Solution structure of a DNA-binding unit of Myb: a helix-turn-helix-related motif with conserved tryptophans forming a hydrophobic core.

1992 • 241 citations

cdc2 Gene Expression at the G ₁ to S Transition in Human T Lymphocytes

1990 • 220 citations

Interactions between functional groups in protein-nucleic acid associations

1982 • 218 citations

Wild-type p53 adopts a ‘mutant’-like conformation when bound to DNA.

1993 • 199 citations

Altered protein conformation on DNA binding by Fos and Jun

1990 • 193 citations

The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.

1992 • 174 citations

The p53 tumor suppressor protein, a modulator of cell proliferation.

1992 • 171 citations

Characterization of the sequence-specific interaction of mouse c-myb protein with DNA.

1990 • 159 citations

In vitro DNA binding activity of Fos/Jun and BZLF1 but not C/EBP is affected by redox changes.

1991 • 156 citations

Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene

1990 • 147 citations

Specific DNA Binding by c-Myb: Evidence for a Double Helix-Turn-Helix-Related Motif

1991 • 143 citations

Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene.

1991 • 130 citations

Reduction of a conserved Cys is essential for Myb DNA-binding

1992 • 129 citations

Expression of the CD4 gene requires a Myb transcription factor.

1992 • 127 citations

c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.

1993 • 125 citations

DNA-induced increase in the .alpha.-helical content of C/EBP and GCN4

1991 • 121 citations

The myb oncogene

1990 • 117 citations

Inhibition of T-cell proliferation by a MYB antisense oligomer is accompanied by selective down-regulation of DNA polymerase alpha expression.

1990 • 96 citations

Redox manipulation of DNA binding activity and BuGR epitope reactivity of the glucocorticoid receptor

1991 • 90 citations

Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis

1991 • 87 citations

Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter.

1990 • 85 citations

Constitutively expressed c-myb abrogates the requirement for insulinlike growth factor 1 in 3T3 fibroblasts.

1991 • 80 citations

Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro.

1992 • 80 citations

Myb protein binds to human immunodeficiency virus 1 long terminal repeat (LTR) sequences and transactivates LTR-mediated transcription.

1990 • 69 citations

The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum.

1992 • 60 citations

A highly conserved cysteine in the v-Myb DNA-binding domain is essential for transformation and transcriptional trans-activation.

1992 • 55 citations

Oncogenic conversion of Ets affects redox regulationin-vivoandin-vitro

1993 • 54 citations

The RxxRxRxxC Motif Conserved in All Rel/κΒ Proteins Is Essential for the DNA-Binding Activity and Redox Regulation of the v-Rel Oncoprotein

1992 • 51 citations

Expression of the CD4 Gene Requires a Myb Transcription Factor

1992 • 50 citations

Interaction of the v-and c-Myb proteins with regulatory sequences of the human c-myc gene.

1991 • 47 citations

Positive Autoregulation of c-myb Expression Via Myb Binding Sites in the 5' Flanking Region of the Human c-myb Gene

1991 • 44 citations

Secondary structure of the DNA‐binding domain of the c‐Myb oncoprotein in solution

1993 • 36 citations

The cellular proto-oncogene product Myb acts as transcriptional activator of the long terminal repeat of human T-lymphotropic virus type I

1992 • 24 citations

The PR264/c-myb connection: expression of a splicing factor modulated by a nuclear protooncogene.

1992 • 23 citations

Functional Analysis of c-Myb Protein in T-Lymphocytic Cell Lines Shows that It trans-Activates the c-myc Promoter

1990 • 17 citations

The transcriptional control proteins c‐Myb and v‐Myb contain a basic region DNA binding motif

1991 • 11 citations

Constitutively Expressed c-myb Abrogates the Requirement for Insulinlike Growth Factor 1 in 3T3 Fibroblasts

1991 • 10 citations