Epidermal growth factor receptor metabolism and protein kinase activity in human A431 cells infected with Snyder-Theilen feline sarcoma virus or harvey or Kirsten murine sarcoma virus

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

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1977 • 947 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

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1979 • 759 citations

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1977 • 670 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

1978 • 578 citations

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1980 • 560 citations

Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells.

1981 • 440 citations

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts

1975 • 432 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells

1976 • 374 citations

Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins

1982 • 366 citations

Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class

1976 • 351 citations

A monoclonal antibody to the human epidermal growth factor receptor

1982 • 342 citations

Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors.

1979 • 300 citations

Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture.

1982 • 280 citations

Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virus

1979 • 270 citations

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

1981 • 244 citations

Kirsten murine sarcoma virus transformed cell lines and a spontaneously transformed rat cell‐line produce transforming factors

1980 • 244 citations

Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport

1970 • 235 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo

1978 • 229 citations

Transforming growth factor(s) production enables cells to grow in the absence of serum: an autocrine system.

1982 • 219 citations

Amphotropic host range of naturally occuring wild mouse leukemia viruses

1976 • 210 citations

Growth factors produced by sarcoma virus-transformed cells.

1978 • 191 citations

Four Different Classes of Retroviruses Induce Phosphorylation of Tyrosines Present in Similar Cellular Proteins

1981 • 178 citations

Epidermal growth factor-receptor-protein kinase interactions.

1981 • 171 citations

Influence of epidermal growth factor (EGF) on ruffling activity, pinocytosis and proliferation of cultivated human glia cells

1976 • 165 citations

Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo Cells

1981 • 158 citations

Detection of phosphotyrosine-containing 34,000-dalton protein in the framework of cells transformed with Rous sarcoma virus.

1981 • 149 citations

Origin and functional properties of the major gene product of the Snyder-Theilen strain of feline sarcoma virus.

1980 • 140 citations

Evidence that viral transforming gene products and epidermal growth factor stimulate phosphorylation of the same cellular protein with similar specificity.

1981 • 137 citations

Action of growth factors in the cell cycle

1979 • 125 citations

Sarcoma growth factor (SGF): Specific binding to epidermal growth factor (EGF) membrane receptors

1980 • 123 citations

Stimulation of sugar uptake in cultured fibroblasts by epidermal growth factor (EGF) and EGF‐binding arginine esterase

1976 • 121 citations

Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.

1981 • 108 citations

Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus.

1975 • 98 citations

Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF

1982 • 95 citations

MSA and EGF receptors on saroma virus transformed cells and human fibrosarcoma cells in culture

1977 • 93 citations

Transforming proteins of some feline and avian sarcoma viruses are related structurally and functionally

1981 • 85 citations

Production and characterization of antibody blocking epidermal growth factor: Receptor interactions

1980 • 74 citations

Properties of a sarcoma‐growth‐factor‐like peptide from cells transformed by a temperature‐sensitive sarcoma virus

1981 • 71 citations

Protein kinases and viral transformation

1982 • 43 citations

Subgenomic fragment of molecular cloned Friend murine leukemia virus DNA contains the gene(s) responsible for Friend murine leukemia virus-induced disease

1980 • 41 citations

Abelson murine leukaemia virus transformation involves loss of epidermal growth factor-binding sites

1980 • 40 citations

Differences in mechanisms of transformation by independent feline sarcoma virus isolates

1981 • 39 citations

Transformation by a Temperature Sensitive Mutant of Rous Sarcoma Virus in the Absence of Serum

1975 • 37 citations

Decrease in epidermal growth factor receptor levels and production of material enhancing epidermal growth factor binding accompany the temperature-dependent changes from normal to transformed phenotype.

1979 • 32 citations

Role of Tyrosine Phosphorylation in Malignant Transformation by Viruses and in Cellular Growth Control

1983 • 27 citations

Role of src gene in growth regulation of Rous sarcoma virus-infected chicken embryo fibroblasts

1980 • 23 citations

Sarcoma Growth Factor: Specific Binding to and Elution from Membrane Receptors for Epidermal Growth Factor

1980 • 12 citations