The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Retention of differentiation potentialities during prolonged cultivation of myogenic cells.

1968 • 975 citations

Functional macrophage cell lines transformed by abelson leukemia virus

1978 • 895 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Two dimensional gel electrophoresis and computer analysis of proteins synthesized by clonal cell lines.

1979 • 759 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1980 • 560 citations

Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells.

1981 • 440 citations

Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus-transforming gene product

1980 • 420 citations

Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins

1982 • 366 citations

CHARACTERIZATION OF A UNIQUE MUSCLE CELL LINE

1974 • 343 citations

Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine

1980 • 328 citations

Transformation by Rous sarcoma virus: effects of src gene expression on the synthesis and phosphorylation of cellular polypeptides.

1979 • 293 citations

Direct transformation of 3T3 cells by Abelson murine leukaemia virus

1975 • 288 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin

1982 • 276 citations

Immunoglobulin synthesis by lymphoid cells transformed in vitro by Abelson murine leukemia virus

1979 • 243 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy.

1978 • 232 citations

Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo

1978 • 229 citations

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

1983 • 225 citations

Complementation Patterns of Thy-1 Variants and Evidence That Antigen Loss Variants “Pre-Exist” in the Parental Population 2

1974 • 204 citations

Four Different Classes of Retroviruses Induce Phosphorylation of Tyrosines Present in Similar Cellular Proteins

1981 • 178 citations

Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

1983 • 166 citations

A strain of Fujinami sarcoma virus which is temperature-sensitive in protein phosphorylation and cellular transformation

1980 • 164 citations

Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo Cells

1981 • 158 citations

Functional EGF receptors are present on mouse embryo tissues

1981 • 154 citations

Detection of phosphotyrosine-containing 34,000-dalton protein in the framework of cells transformed with Rous sarcoma virus.

1981 • 149 citations

A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product

1979 • 146 citations

The 34 kd pp60src substrate is located at the inner face of the plasma membrane

1983 • 142 citations

Identification and characterization of cellular targets for tyrosine protein kinases.

1983 • 139 citations

Evidence that viral transforming gene products and epidermal growth factor stimulate phosphorylation of the same cellular protein with similar specificity.

1981 • 137 citations

Cellular Sequences Related to Three New onc Genes of Avian Sarcoma Virus ( fps, yes , and ros ) and Their Expression in Normal and Transformed Cells

1982 • 131 citations

Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.

1981 • 113 citations

Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.

1981 • 108 citations

Subcellular Location of an Abundant Substrate (p36) for Tyrosine-Specific Protein Kinases

1983 • 103 citations

Membrane association of a 36,000-dalton substrate for tyrosine phosphorylation in chicken embryo fibroblasts transformed by avian sarcoma viruses.

1983 • 89 citations

Transforming proteins of some feline and avian sarcoma viruses are related structurally and functionally

1981 • 85 citations

Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane.

1983 • 85 citations

Correlation between glucocorticoid receptor and cytolytic response of murine lymphoid cell lines.

1979 • 76 citations

Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts.

1982 • 73 citations

Studies on Surface Antigen Variants. Isolation of Two Complementary Variants for Thy 1.22

1973 • 73 citations

A new determinant of glucocorticoid sensitivity in lymphoid cell lines.

1983 • 72 citations

Identification of Phosphotyrosine-Containing Proteins in Untransformed and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts

1982 • 71 citations

Changes in the distribution of the 34-kdalton tyrosine kinase substrate during differentiation and maturation of chicken tissues.

1984 • 69 citations

The p36 substrate of tyrosine-specific protein kinases co-localizes with non-erythrocyte alpha-spectrin antigen, p230, in surface lamina of cultured fibroblasts.

1983 • 64 citations

The same normal cell protein is phosphorylated after transformation by avian sarcoma viruses with unrelated transforming genes.

1981 • 63 citations

Role of p60src kinase activity in the induction of neuroretinal cell proliferation by rous sarcoma virus

1982 • 60 citations

Cell-Specific Antigens and Immunoglobulin Synthesis of Murine Myeloma Cells and Their Variants<xref ref-type="fn" rid="FN2">2</xref>

1972 • 57 citations

Induction of T-cell maturation by a cloned line of thymic epithelium (TEPI).

1983 • 47 citations

Identification of Phosphotyrosine-Containing Proteins in Untransformed and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts

1982 • 45 citations

Protein kinases and viral transformation

1982 • 43 citations

Comparison of the 34,000-Da pp60src substrate and a 38,000-Da phosphoprotein identified by monoclonal antibodies.

1983 • 42 citations

Association of pp36, a phosphorylated form of the presumed target protein for the src protein of Rous sarcoma virus, with the membrane of chicken cells transformed by Rous sarcoma virus.

1983 • 33 citations

Some lymphoid cell lines transformed by Abelson murine leukemia virus lack a major 36,000-dalton tyrosine protein kinase substrate.

1983 • 27 citations

Phosphorylation of the Mr = 34,000 protein in normal and Rous sarcoma virus-transformed rat fibroblasts

1982 • 24 citations

The Same Normal Cell Protein Is Phosphorylated After Transformation by Avian Sarcoma Viruses with Unrelated Transforming Genes

1981 • 23 citations

Phosphoprotein associated with activation of the src gene product in myogenic cells

1980 • 22 citations

Neoplasms of Immunoglobulin-Producing Cells in Mice

1978 • 14 citations

Comparison between Muscle and Liver Enolases and Their Behavior during Differentiation and Growth

1975 • 14 citations

Some Lymphoid Cell Lines Transformed by Abelson Murine Leukemia Virus Lack a Major 36,000-Dalton Tyrosine Protein Kinase Substrate

1983 • 10 citations